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European Archives of Oto-Rhino-Laryngology

Published in:

01-06-2010 | REVIEW ARTICLE

Current potential and limitations of molecular diagnostic methods in head and neck cancer

Authors: Magdy E. Mahfouz, Juan P. Rodrigo, Robert P. Takes, Mohamed N. Elsheikh, Alessandra Rinaldo, Ruud H. Brakenhoff, Alfio Ferlito

Published in: European Archives of Oto-Rhino-Laryngology | Issue 6/2010

Abstract

Traditional diagnostic methods such as clinical assessment, histopathological examination and imaging techniques are limited in their capacity to provide information on prognosis and treatment choice of head and neck cancer. In recent years, molecular techniques have been developed that enabled us to get more insight into the molecular biological cellular pathways underlying tumor progression and metastasis. Correlation of these molecular changes with clinical events has been explored. However, consistently useful markers have not been identified yet, although many promising developments are in progress. It may be expected that in the near future, molecular markers will be useful for clinical purposes. In this paper, an overview will be given of the several molecular techniques that may have potential to be introduced in clinical practice in the management of head and neck squamous cell carcinoma.

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Title: Current potential and limitations of molecular diagnostic methods in head and neck cancer
Authors: Magdy E. Mahfouz
Juan P. Rodrigo
Robert P. Takes
Mohamed N. Elsheikh
Alessandra Rinaldo
Ruud H. Brakenhoff
Alfio Ferlito
Publication date: 01-06-2010
Publisher: Springer-Verlag
Published in: European Archives of Oto-Rhino-Laryngology / Issue 6/2010
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-009-1177-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Current potential and limitations of molecular diagnostic methods in head and neck cancer

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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