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Archives of Gynecology and Obstetrics

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01-07-2015 | General Gynecology

A single dose of misoprostol for reducing hemorrhage during myomectomy: a randomized clinical trial

Authors: Nasrin Niroomand, Shima Hajiha, Nasrin Moghadami Tabrizi, Mahsa Ghajarzadeh

Published in: Archives of Gynecology and Obstetrics | Issue 1/2015

Abstract

Purpose

To evaluate the effect of vaginal misoprostol on intraoperative bleeding during myomectomy.

Method

In this randomized clinical trial, 80 women with myomas were randomly assigned to receive 200 µg misoprostol or placebo (vitamin B₆) 3 h before surgery. Blood loss during surgery, postoperative need for blood transfusion, and the hemoglobin level before surgery, and 6 and 12 h after surgery were assessed in two groups.

Results

Mean age and the mean preoperative and postoperative Hb levels were not significantly different between the two groups. Mean duration of surgery and mean estimated blood loss were significantly higher in control group. Nine (22.5 %) patients in control group needed blood transfusion while there was no need blood transfusion in misoprostol group (p = 0.001).

Conclusion

A single dose of vaginal misoprostol is effective in reducing hemorrhage during myomectomy.

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Title: A single dose of misoprostol for reducing hemorrhage during myomectomy: a randomized clinical trial
Authors: Nasrin Niroomand
Shima Hajiha
Nasrin Moghadami Tabrizi
Mahsa Ghajarzadeh
Publication date: 01-07-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 1/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-015-3617-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A single dose of misoprostol for reducing hemorrhage during myomectomy: a randomized clinical trial

Abstract

Purpose

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Method

Results

Conclusion

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