Skip to main content
Top
Published in: Archives of Orthopaedic and Trauma Surgery 3/2012

01-03-2012 | Arthroscopy and Sports Medicine

Supplemental bio-tenodesis improves tibialis anterior allograft yield load in extremely low density tibiae

Authors: Brent Walz, John Nyland, Brent Fisher, Ryan Krupp, Akbar Nawab

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 3/2012

Login to get access

Abstract

Introduction

Improved soft tissue tendon graft mechanical properties have led to their increased use for anterior cruciate ligament (ACL) reconstruction. Because they do not have an osseous component; however, there are greater concerns regarding tibial graft slippage during early postoperative rehabilitation and activities of daily living, particularly in patients with poor bone mineral density (BMD), such as older patients, women, smokers, and patients undergoing revision ACL reconstruction surgery.

Methods

This in vitro biomechanical study attempted to determine the effectiveness of supplemental ACL graft fixation in low BMD tibiae. Eight paired knees (16 specimens) were harvested from female cadavers (mean age = 76, range = 60–88 years). Tibiae were assigned to either a combination bioabsorbable interference screw, bio-tenodesis screw group (Group 1, n = 8, apparent BMD = 0.44 ± 0.13 g/cm2) or a bioabsorbable interference screw group (Group 2, n = 8, apparent BMD = 0.44 ± 0.14 g/cm2). Double-strand (single loop) tibialis anterior tendon allografts were fixed in matched diameter tibial tunnels. Using a custom 6° of freedom jig, potted constructs were mounted on to a servo hydraulic device with the axial loading force aligned directly with the tibial tunnel. Constructs underwent progressive cyclic tensile loading from 10 to 150 N with a 25 N load increase every 20 cycles. This was followed by yield load to failure testing (20 mm/min).

Results

Groups did not display displacement differences during progressive cyclic loading. Group 1 (312.7 ± 67.5 N) displayed 25% greater yield load at failure than Group 2 (235.0 ± 47.6 N), P = 0.045. Both groups displayed fixation levels well below the previously reported minimal safe threshold estimate for early unrestricted weight bearing, accelerated rehabilitation and activities of daily living.

Conclusion

Supplemental bio-tenodesis fixation may improve early tibial-soft tissue tendon graft fixation in patients that have poor tibial BMD, but study results suggest that both methods may require weightbearing, rehabilitation, and activity of daily living restrictions during the early postoperative period to prevent graft slippage.
Literature
1.
go back to reference Sievanen H, Kannus P, Heinonen A, Oja P, Vuori I (1994) Bone mineral density and muscle strength of lower extremities after long-term strength training, subsequent knee ligament injury and rehabilitation: a unique 2-year follow-up of a 26-year-old female student. Bone 15:85–90PubMedCrossRef Sievanen H, Kannus P, Heinonen A, Oja P, Vuori I (1994) Bone mineral density and muscle strength of lower extremities after long-term strength training, subsequent knee ligament injury and rehabilitation: a unique 2-year follow-up of a 26-year-old female student. Bone 15:85–90PubMedCrossRef
2.
go back to reference Nyland J, Fisher B, Brand E, Krupp R, Caborn DN (2010) Osseous deficits after anterior cruciate ligament injury and reconstruction: a systematic review with suggestions to improve osseous homeostasis. Arthroscopy 26:1248–1257PubMedCrossRef Nyland J, Fisher B, Brand E, Krupp R, Caborn DN (2010) Osseous deficits after anterior cruciate ligament injury and reconstruction: a systematic review with suggestions to improve osseous homeostasis. Arthroscopy 26:1248–1257PubMedCrossRef
3.
go back to reference Andersson SM, Nilsson BE (1979) Changes in bone mineral content following ligamentous knee injuries. Med Sci Sports 11:351–353PubMedCrossRef Andersson SM, Nilsson BE (1979) Changes in bone mineral content following ligamentous knee injuries. Med Sci Sports 11:351–353PubMedCrossRef
4.
go back to reference Leppala J, Kannus P, Natri A, Pasanen M, Sievanen H, Vuori I, Jarvinen M (1999) Effect of anterior cruciate ligament injury of the knee on bone mineral density of the spine and affected lower extremity: a prospective one-year follow-up study. Calcif Tissue Int 64:357–363PubMedCrossRef Leppala J, Kannus P, Natri A, Pasanen M, Sievanen H, Vuori I, Jarvinen M (1999) Effect of anterior cruciate ligament injury of the knee on bone mineral density of the spine and affected lower extremity: a prospective one-year follow-up study. Calcif Tissue Int 64:357–363PubMedCrossRef
5.
go back to reference Kannus P, Sievanen H, Jarvinen M, Heinonen A, Oja P, Vuori I (1992) A cruciate ligament injury produces considerable permanent osteoporosis in the affected knee. J Bone Miner Res 7:1429–1434PubMedCrossRef Kannus P, Sievanen H, Jarvinen M, Heinonen A, Oja P, Vuori I (1992) A cruciate ligament injury produces considerable permanent osteoporosis in the affected knee. J Bone Miner Res 7:1429–1434PubMedCrossRef
6.
go back to reference Klein SA, Nyland J, Caborn DN, Kocabey Y, Nawab A (2005) Comparison of volumetric bone mineral density in the tibial region of interest for ACL reconstruction. Surg Radiol Anat 27:372–376PubMedCrossRef Klein SA, Nyland J, Caborn DN, Kocabey Y, Nawab A (2005) Comparison of volumetric bone mineral density in the tibial region of interest for ACL reconstruction. Surg Radiol Anat 27:372–376PubMedCrossRef
7.
go back to reference Vuori I, Heinonen A, Sievanen H, Kannus M, Pasanen M, Oja P (1994) Effects of unilateral strength training and detraining on bone mineral density and content in young women: a study of mechanical loading and deloading on human bones. Calcif Tissue Int 55:59–67PubMedCrossRef Vuori I, Heinonen A, Sievanen H, Kannus M, Pasanen M, Oja P (1994) Effects of unilateral strength training and detraining on bone mineral density and content in young women: a study of mechanical loading and deloading on human bones. Calcif Tissue Int 55:59–67PubMedCrossRef
8.
go back to reference Bailey SB, Grover DM, Howell SM, Hull ML (2004) Foam-reinforced elderly human tibia approximates young human tibia better than porcine tibia. Am J Sports Med 32:755–764PubMedCrossRef Bailey SB, Grover DM, Howell SM, Hull ML (2004) Foam-reinforced elderly human tibia approximates young human tibia better than porcine tibia. Am J Sports Med 32:755–764PubMedCrossRef
9.
go back to reference Klein SA, Nyland J, Kocabey Y, Wozniak T, Nawab A, Caborn DN (2004) Tendon graft fixation in ACL reconstruction: in vitro evaluation of bioabsorbable tenodesis screw. Acta Orthop Scand 75:84–88PubMedCrossRef Klein SA, Nyland J, Kocabey Y, Wozniak T, Nawab A, Caborn DN (2004) Tendon graft fixation in ACL reconstruction: in vitro evaluation of bioabsorbable tenodesis screw. Acta Orthop Scand 75:84–88PubMedCrossRef
10.
go back to reference Kuechle DK, Pearson SE, Beach WR, Freeman EL, Pawlowski DF, Whipple TL, Caspari Dagger RB, Meyers JF (2002) Allograft anterior cruciate ligament reconstruction in patients over 40 years of age. Arthroscopy 18:845–853PubMedCrossRef Kuechle DK, Pearson SE, Beach WR, Freeman EL, Pawlowski DF, Whipple TL, Caspari Dagger RB, Meyers JF (2002) Allograft anterior cruciate ligament reconstruction in patients over 40 years of age. Arthroscopy 18:845–853PubMedCrossRef
11.
go back to reference Dahm DL, Wulf CA, Dajani KA, Dobbs RE, Levy BA, Stuart MA (2008) Reconstruction of the anterior cruciate ligament in patients over 50 years. J Bone Joint Surg Br 90:1446–1450PubMedCrossRef Dahm DL, Wulf CA, Dajani KA, Dobbs RE, Levy BA, Stuart MA (2008) Reconstruction of the anterior cruciate ligament in patients over 50 years. J Bone Joint Surg Br 90:1446–1450PubMedCrossRef
12.
go back to reference Arbuthnot JE, Brink RB (2010) The role of anterior cruciate ligament reconstruction in the older patients, 55 years or above. Knee Surg Sports Traumatol Arthrosc 18:73–78PubMedCrossRef Arbuthnot JE, Brink RB (2010) The role of anterior cruciate ligament reconstruction in the older patients, 55 years or above. Knee Surg Sports Traumatol Arthrosc 18:73–78PubMedCrossRef
13.
go back to reference Marquass B, Hepp P, Engel T, Dusing T, Lill H, Josten C (2007) The use of hamstrings in anterior cruciate ligament reconstruction in patients over 40 years. Arch Orthop Trauma Surg 127:835–843PubMedCrossRef Marquass B, Hepp P, Engel T, Dusing T, Lill H, Josten C (2007) The use of hamstrings in anterior cruciate ligament reconstruction in patients over 40 years. Arch Orthop Trauma Surg 127:835–843PubMedCrossRef
14.
go back to reference Osti L, Papalia R, Del Buono A, Leonardi F, Denaro V, Maffulli N (2011) Surgery for ACL deficiency in patients over 50. Knee Surg Sports Traumatol Arthrosc 19:412–417PubMedCrossRef Osti L, Papalia R, Del Buono A, Leonardi F, Denaro V, Maffulli N (2011) Surgery for ACL deficiency in patients over 50. Knee Surg Sports Traumatol Arthrosc 19:412–417PubMedCrossRef
15.
go back to reference Plancher KD, Steadman JR, Briggs KK, Hutton KS (1998) Reconstruction of the anterior cruciate ligament in patients who are at least forty years old. A long-term follow-up and outcome study. J Bone Joint Surg Am 80:184–197PubMedCrossRef Plancher KD, Steadman JR, Briggs KK, Hutton KS (1998) Reconstruction of the anterior cruciate ligament in patients who are at least forty years old. A long-term follow-up and outcome study. J Bone Joint Surg Am 80:184–197PubMedCrossRef
16.
go back to reference Trojani C, Sane J-C, Coste J-S, Boileau P (2009) Four-strand hamstring tendon autograft for ACL reconstruction in patients aged 50 years or older. Orthop Traumatol Surg Res 95:22–27PubMedCrossRef Trojani C, Sane J-C, Coste J-S, Boileau P (2009) Four-strand hamstring tendon autograft for ACL reconstruction in patients aged 50 years or older. Orthop Traumatol Surg Res 95:22–27PubMedCrossRef
17.
go back to reference Viola R, Vianello R (1999) Intra-articular ACL reconstruction in the over-40-year-old patient. Knee Surg Sports Traumatol Arthrosc 7:25–28PubMedCrossRef Viola R, Vianello R (1999) Intra-articular ACL reconstruction in the over-40-year-old patient. Knee Surg Sports Traumatol Arthrosc 7:25–28PubMedCrossRef
18.
go back to reference Haut Donahue TL, Howell SM, Hull ML, Gregersen C (2002) A biomechanical evaluation of anterior and posterior tibialis tendons as suitable single-loop anterior cruciate ligament grafts. Arthroscopy 18:589–597PubMedCrossRef Haut Donahue TL, Howell SM, Hull ML, Gregersen C (2002) A biomechanical evaluation of anterior and posterior tibialis tendons as suitable single-loop anterior cruciate ligament grafts. Arthroscopy 18:589–597PubMedCrossRef
19.
go back to reference Lu Y, Markel MD, Nemke B, Wynn S, Graf B (2009) Comparison of single- versus double-tunnel tendon-to-bone healing in an ovine model: a biomechanical and histological analysis. Am J Sports Med 37:512–517PubMedCrossRef Lu Y, Markel MD, Nemke B, Wynn S, Graf B (2009) Comparison of single- versus double-tunnel tendon-to-bone healing in an ovine model: a biomechanical and histological analysis. Am J Sports Med 37:512–517PubMedCrossRef
20.
go back to reference Rodeo SA, Arnoczky SP, Torzilli PA, Hidaka C, Warren RF (1993) Tendon-healing in a bone tunnel: a biomechanical and histological study in the dog. J Bone Joint Surg Am 75:1795–1803PubMed Rodeo SA, Arnoczky SP, Torzilli PA, Hidaka C, Warren RF (1993) Tendon-healing in a bone tunnel: a biomechanical and histological study in the dog. J Bone Joint Surg Am 75:1795–1803PubMed
21.
go back to reference Scranton PE, Lanzer WL, Ferguson MS, Kirkman TR, Pflaster DS (1998) Mechanisms of anterior cruciate ligament neovascularization and ligamentization. Arthroscopy 14:702–716PubMedCrossRef Scranton PE, Lanzer WL, Ferguson MS, Kirkman TR, Pflaster DS (1998) Mechanisms of anterior cruciate ligament neovascularization and ligamentization. Arthroscopy 14:702–716PubMedCrossRef
22.
go back to reference Scheffler SU, Schmidt T, Gangey I, Dustmann M, Unterhauser F, Weiler A (2008) Fresh-frozen free-tendon allografts versus autografts in anterior cruciate ligament reconstruction: delayed remodeling and inferior mechanical function during long-term healing in sheep. Arthroscopy 24:448–458PubMedCrossRef Scheffler SU, Schmidt T, Gangey I, Dustmann M, Unterhauser F, Weiler A (2008) Fresh-frozen free-tendon allografts versus autografts in anterior cruciate ligament reconstruction: delayed remodeling and inferior mechanical function during long-term healing in sheep. Arthroscopy 24:448–458PubMedCrossRef
23.
go back to reference Brand JC Jr, Pienkowski D, Steenlage E, Hamilton D, Johnson DL, Caborn DN (2000) Interference screw fixation strength of a quadrupled hamstring tendon graft is directly related to bone mineral density and insertion torque. Am J Sports Med 28:705–710PubMed Brand JC Jr, Pienkowski D, Steenlage E, Hamilton D, Johnson DL, Caborn DN (2000) Interference screw fixation strength of a quadrupled hamstring tendon graft is directly related to bone mineral density and insertion torque. Am J Sports Med 28:705–710PubMed
24.
go back to reference Anderson SD (2006) Practical light embalming technique for use in the surgical fresh tissue dissection laboratory. Clin Anat 19:8–11PubMedCrossRef Anderson SD (2006) Practical light embalming technique for use in the surgical fresh tissue dissection laboratory. Clin Anat 19:8–11PubMedCrossRef
25.
go back to reference Ohman C, Dall’Ara E, Baleani M, Van Sint Jan S, Viceconti M (2008) The effects of embalming using 4% formalin solution on the compressive mechanical properties of human cortical bone. Clin Biomech 23:1294–1298CrossRef Ohman C, Dall’Ara E, Baleani M, Van Sint Jan S, Viceconti M (2008) The effects of embalming using 4% formalin solution on the compressive mechanical properties of human cortical bone. Clin Biomech 23:1294–1298CrossRef
26.
go back to reference Sedlin ED, Hirsch C (1966) Factors affecting the determination of the physical properties of femoral cortical bone. Acta Orthop Scand 37:29–48PubMedCrossRef Sedlin ED, Hirsch C (1966) Factors affecting the determination of the physical properties of femoral cortical bone. Acta Orthop Scand 37:29–48PubMedCrossRef
27.
go back to reference Charlick DA, Caborn DN (2000) Technical note: alternative soft-tissue graft preparation technique for cruciate ligament reconstruction. Arthroscopy 16:E20PubMedCrossRef Charlick DA, Caborn DN (2000) Technical note: alternative soft-tissue graft preparation technique for cruciate ligament reconstruction. Arthroscopy 16:E20PubMedCrossRef
28.
go back to reference Goble EM, Downey DJ, Wilcox TR (1995) Positioning of the tibial tunnel for anterior cruciate ligament reconstruction. Arthroscopy 11:688–695PubMedCrossRef Goble EM, Downey DJ, Wilcox TR (1995) Positioning of the tibial tunnel for anterior cruciate ligament reconstruction. Arthroscopy 11:688–695PubMedCrossRef
29.
go back to reference Howell SM, Wallace MP, Hull ML, Deutsch ML (1999) Evaluation of the single-incision arthroscopic technique for anterior cruciate ligament replacement. A study of tibial tunnel placement, intraoperative graft tension, and stability. Am J Sports Med 27:284–293PubMed Howell SM, Wallace MP, Hull ML, Deutsch ML (1999) Evaluation of the single-incision arthroscopic technique for anterior cruciate ligament replacement. A study of tibial tunnel placement, intraoperative graft tension, and stability. Am J Sports Med 27:284–293PubMed
30.
go back to reference Morrison JB (1969) Function of the knee joint in various activities. Biomed Eng 4:573–580PubMed Morrison JB (1969) Function of the knee joint in various activities. Biomed Eng 4:573–580PubMed
31.
go back to reference Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS (1984) Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am 66:344–352PubMed Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS (1984) Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am 66:344–352PubMed
32.
go back to reference Noyes FR, Butler DL, Paulos LE, Grood ES (1983) Intra-articular cruciate reconstruction. I: Perspectives on graft strength, vascularization, and immediate motion after replacement. Clin Orthop Rel Res 172:71–77 Noyes FR, Butler DL, Paulos LE, Grood ES (1983) Intra-articular cruciate reconstruction. I: Perspectives on graft strength, vascularization, and immediate motion after replacement. Clin Orthop Rel Res 172:71–77
33.
go back to reference Jarvinen TLN, Alami GB, Karlsson J (2010) Anterior cruciate ligament graft fixation—a myth busted? Arthroscopy 26:681–684PubMedCrossRef Jarvinen TLN, Alami GB, Karlsson J (2010) Anterior cruciate ligament graft fixation—a myth busted? Arthroscopy 26:681–684PubMedCrossRef
Metadata
Title
Supplemental bio-tenodesis improves tibialis anterior allograft yield load in extremely low density tibiae
Authors
Brent Walz
John Nyland
Brent Fisher
Ryan Krupp
Akbar Nawab
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 3/2012
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-011-1374-6

Other articles of this Issue 3/2012

Archives of Orthopaedic and Trauma Surgery 3/2012 Go to the issue

Arthroscopy and Sports Medicine

Isolated AL bundle reconstruction of the PCL