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Open Access 01-03-2008 | Review

Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach

Authors: Tanja Kuhlmann, Hans Lassmann, Wolfgang Brück

Published in: Acta Neuropathologica | Issue 3/2008

Abstract

Multiple sclerosis is the most frequent demyelinating disease in adults. It is characterized by demyelination, inflammation, gliosis and a variable loss of axons. Clinically and histologically, it shares features with other demyelinating and/or inflammatory CNS diseases. Diagnosis of an inflammatory demyelinating disease can be challenging, especially in small biopsy specimens. Here, we summarize the histological hallmarks and most important neuropathological differential diagnoses of early MS, and provide practical guidelines for the diagnosis of inflammatory demyelinating diseases.

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Title: Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach
Authors: Tanja Kuhlmann
Hans Lassmann
Wolfgang Brück
Publication date: 01-03-2008
Publisher: Springer-Verlag
Published in: Acta Neuropathologica / Issue 3/2008
Print ISSN: 0001-6322
Electronic ISSN: 1432-0533
DOI: https://doi.org/10.1007/s00401-007-0320-8

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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