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Open Access 01-09-2009 | Review

Coronary microvascular resistance: methods for its quantification in humans

Authors: Paul Knaapen, Paolo G. Camici, Koen M. Marques, Robin Nijveldt, Jeroen J. Bax, Nico Westerhof, Marco J. W. Götte, Michael Jerosch-Herold, Heinrich R. Schelbert, Adriaan A. Lammertsma, Albert C. van Rossum

Published in: Basic Research in Cardiology | Issue 5/2009

Abstract

Coronary microvascular dysfunction is a topic that has recently gained considerable interest in the medical community owing to the growing awareness that microvascular dysfunction occurs in a number of myocardial disease states and has important prognostic implications. With this growing awareness, comes the desire to accurately assess the functional capacity of the coronary microcirculation for diagnostic purposes as well as to monitor the effects of therapeutic interventions that are targeted at reversing the extent of coronary microvascular dysfunction. Measurements of coronary microvascular resistance play a pivotal role in achieving that goal and several invasive and noninvasive methods have been developed for its quantification. This review is intended to provide an update pertaining to the methodology of these different imaging techniques, including the discussion of their strengths and weaknesses.

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Title: Coronary microvascular resistance: methods for its quantification in humans
Authors: Paul Knaapen
Paolo G. Camici
Koen M. Marques
Robin Nijveldt
Jeroen J. Bax
Nico Westerhof
Marco J. W. Götte
Michael Jerosch-Herold
Heinrich R. Schelbert
Adriaan A. Lammertsma
Albert C. van Rossum
Publication date: 01-09-2009
Publisher: D. Steinkopff-Verlag
Published in: Basic Research in Cardiology / Issue 5/2009
Print ISSN: 0300-8428
Electronic ISSN: 1435-1803
DOI: https://doi.org/10.1007/s00395-009-0037-z

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Coronary microvascular resistance: methods for its quantification in humans

Abstract

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