Published in:
01-04-2015 | Reply
Intracellular receptor regulation of adipose metabolism by the isoflavone genistein
Authors:
Isabella Zanella, Diego Di Lorenzo
Published in:
European Journal of Nutrition
|
Issue 3/2015
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Excerpt
In the last few lines of his letter, Dr. Chirumbolo concludes that the complex action of genistein in the modulation of adipose metabolism and growth is dependent on several factors among which the most relevant are its plasma concentration, its nuclear receptor-mediated signaling and the gender. I would add that the dietary background is itself a factor that may shift the variable effect of genistein on adipose metabolism from negative (inhibitory control) to positive (stimulation), influencing the gut microbiota and intestinal metabolization, absorption and bioavailability. …