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Published in: European Journal of Nutrition 2/2014

01-03-2014 | Original Contribution

Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II)

Authors: Anna Vogiatzoglou, Thorsten Heuer, Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Gunter G. C. Kuhnle

Published in: European Journal of Nutrition | Issue 2/2014

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Abstract

Background/Objectives

Data from intervention studies suggest a beneficial effect of flavanols on vascular health. However, insufficient data on their intake have delayed the assessment of their health benefits. The aim of this study was to estimate intake of flavanols and their main sources among people living in Germany.

Subjects/Methods

Data from diet history interviews of the German National Nutrition Survey II for 15,371 people across Germany aged 14–80 years were analyzed. The FLAVIOLA Flavanol Food Composition Database was compiled using the latest US Department of Agriculture and Phenol-Explorer Databases and expanded to include recipes and retention factors.

Results

Mean intake of total flavanols, flavan-3-ol monomers, proanthocyanidins (PA), and theaflavins in Germany was 386, 120, 196, and 70 mg/day, respectively. Women had higher intakes of total flavanols (399 mg/day) than men (372 mg/day) in all age groups, with the exception of the elderly. Similar results were observed for monomers (108 mg/day for men, 131 mg/day for women) and PA (190 mg/day; 203 mg/day), although intake of theaflavins was higher in men (74 mg/day; 66 mg/day). There was an age gradient with an increase in total flavanols, monomers, and theaflavins across the age groups. The major contributor of total flavanols in all subjects was pome fruits (27 %) followed by black tea (25 %).

Conclusions

This study demonstrated age- and sex-related variations in the intake and sources of dietary flavanols in Germany. The current analysis will provide a valuable tool in clarifying and confirming the potential health benefits of flavanols.
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Literature
2.
go back to reference Hooper L, Kay C, Abdelhamid A, Kroon PA, Cohn JS, Rimm EB, Cassidy A (2012) Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am J Clin Nutr 95:740–751. doi:10.3945/ajcn.111.023457 CrossRef Hooper L, Kay C, Abdelhamid A, Kroon PA, Cohn JS, Rimm EB, Cassidy A (2012) Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am J Clin Nutr 95:740–751. doi:10.​3945/​ajcn.​111.​023457 CrossRef
3.
go back to reference Cassidy A, O’Reilly EJ, Kay C, Sampson L, Franz M, Forman J, Curhan G, Rimm EB (2011) Habitual intake of flavonoid subclasses and incident hypertension in adults. Am J Clin Nutr 93:338–347. doi:10.3945/ajcn.110.006783 CrossRef Cassidy A, O’Reilly EJ, Kay C, Sampson L, Franz M, Forman J, Curhan G, Rimm EB (2011) Habitual intake of flavonoid subclasses and incident hypertension in adults. Am J Clin Nutr 93:338–347. doi:10.​3945/​ajcn.​110.​006783 CrossRef
4.
go back to reference Mink PJ, Scrafford CG, Barraj LM, Harnack L, Hong C-P, Nettleton JA, Jacobs DR (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 85:895–909 Mink PJ, Scrafford CG, Barraj LM, Harnack L, Hong C-P, Nettleton JA, Jacobs DR (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 85:895–909
5.
go back to reference Santos-Buelga C, Scalbert A (2000) Proanthocyanidins and tannin-like compounds: nature, occurrence, dietary intake and effects on nutrition and health. J Sci Food Agric 80:1094–1117CrossRef Santos-Buelga C, Scalbert A (2000) Proanthocyanidins and tannin-like compounds: nature, occurrence, dietary intake and effects on nutrition and health. J Sci Food Agric 80:1094–1117CrossRef
6.
go back to reference Arts IC, van De Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 2. Tea, wine, fruit juices, and chocolate milk. J Agric Food Chem 48:1752–1757CrossRef Arts IC, van De Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 2. Tea, wine, fruit juices, and chocolate milk. J Agric Food Chem 48:1752–1757CrossRef
7.
go back to reference Arts IC, van de Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods. J Agric Food Chem 48:1746–1751CrossRef Arts IC, van de Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods. J Agric Food Chem 48:1746–1751CrossRef
8.
go back to reference Gu L, Kelm MA, Hammerstone JF, Beecher G, Holden J, Haytowitz D, Gebhardt S, Prior RL (2004) Concentrations of proanthocyanidins in common foods and estimations of normal consumption. J Nutr 134:613–617 Gu L, Kelm MA, Hammerstone JF, Beecher G, Holden J, Haytowitz D, Gebhardt S, Prior RL (2004) Concentrations of proanthocyanidins in common foods and estimations of normal consumption. J Nutr 134:613–617
9.
go back to reference Beecher GR (2003) Overview of dietary flavonoids: nomenclature, occurrence and intake. J Nutr 133:3248S–3254S Beecher GR (2003) Overview of dietary flavonoids: nomenclature, occurrence and intake. J Nutr 133:3248S–3254S
10.
go back to reference Crozier A, Lean M, McDonald M, Black C (1997) Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuces, and celery. J Agric Food Chem 45:590–595CrossRef Crozier A, Lean M, McDonald M, Black C (1997) Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuces, and celery. J Agric Food Chem 45:590–595CrossRef
11.
go back to reference Neveu V, Perez-Jimenez J, Vos F, Crespy V, du Chaffaut L, Mennen L, Knox C, Eisner R, Cruz J, Wishart D, Scalbert A (2010) Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxford) 2010:bap024. doi:10.1093/database/bap024 Neveu V, Perez-Jimenez J, Vos F, Crespy V, du Chaffaut L, Mennen L, Knox C, Eisner R, Cruz J, Wishart D, Scalbert A (2010) Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxford) 2010:bap024. doi:10.​1093/​database/​bap024
16.
go back to reference Krems C, Bauch A, Götz A, Heuer T, Hild A, Möseneder J, Brombach C (2006) Methoden der Nationalen Verzehrsstudie II (Methods of the National Nutrition Survey II). Ernahrungs Umschau 53:44–50 Krems C, Bauch A, Götz A, Heuer T, Hild A, Möseneder J, Brombach C (2006) Methoden der Nationalen Verzehrsstudie II (Methods of the National Nutrition Survey II). Ernahrungs Umschau 53:44–50
17.
go back to reference Welch AA, McTaggart A, Mulligan AA, Luben R, Walker N, Khaw KT, Day NE, Bingham SA (2001) DINER (Data Into Nutrients for Epidemiological Research)—a new data-entry program for nutritional analysis in the EPIC-Norfolk cohort and the 7-day diary method. Public Health Nutr 4:1253–1265CrossRef Welch AA, McTaggart A, Mulligan AA, Luben R, Walker N, Khaw KT, Day NE, Bingham SA (2001) DINER (Data Into Nutrients for Epidemiological Research)—a new data-entry program for nutritional analysis in the EPIC-Norfolk cohort and the 7-day diary method. Public Health Nutr 4:1253–1265CrossRef
18.
go back to reference Hilbig A, Heuer T, Krems C, Straßburg A, Eisinger-Watzl M, Heyer A, Tschida A, Götz A, Pfau C (2009) Wie isst Deutschland? Auswertungen der Nationalen Verzehrsstudie II zum Lebensmittelverzehr (What does Germany eat? Evaluation of the National Nutrition Survey II with respect to food consumption). Ernaehrungs Umschau 56:16–23 Hilbig A, Heuer T, Krems C, Straßburg A, Eisinger-Watzl M, Heyer A, Tschida A, Götz A, Pfau C (2009) Wie isst Deutschland? Auswertungen der Nationalen Verzehrsstudie II zum Lebensmittelverzehr (What does Germany eat? Evaluation of the National Nutrition Survey II with respect to food consumption). Ernaehrungs Umschau 56:16–23
20.
go back to reference Rand WA, Pennington JAT, Murphy SP, Klensin JC (1991) Compiling data for food composition data bases. United Nations University Press, Tokyo Rand WA, Pennington JAT, Murphy SP, Klensin JC (1991) Compiling data for food composition data bases. United Nations University Press, Tokyo
21.
go back to reference Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MAH, Heiss C, Kelm M, Merx M, Spencer JPE, Schroeter H, Kuhnle GGC (2013) Estimated dietary intakes of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union (submitted) Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MAH, Heiss C, Kelm M, Merx M, Spencer JPE, Schroeter H, Kuhnle GGC (2013) Estimated dietary intakes of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union (submitted)
22.
go back to reference Knaze V, Zamora-Ros R, Lujan-Barroso L, Romieu I, Scalbert A, Slimani N, Riboli E, van Rossum CT, Bueno-de-Mesquita HB, Trichopoulou A, Dilis V, Tsiotas K, Skeie G, Engeset D, Ramon Quiros J, Molina E, Huerta JM, Crowe F, Wirfal E, Ericson U, Peeters PH, Kaaks R, Teucher B, Johansson G, Johansson I, Tumino R, Boeing H, Drogan D, Amiano P, Mattiello A, Khaw KT, Luben R, Krogh V, Ardanaz E, Sacerdote C, Salvini S, Overvad K, Tjonneland A, Olsen A, Boutron-Ruault MC, Fagherazzi G, Perquier F, Gonzalez CA (2012) Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Br J Nutr 108:1095–1108. doi:10.1017/S0007114511006386 CrossRef Knaze V, Zamora-Ros R, Lujan-Barroso L, Romieu I, Scalbert A, Slimani N, Riboli E, van Rossum CT, Bueno-de-Mesquita HB, Trichopoulou A, Dilis V, Tsiotas K, Skeie G, Engeset D, Ramon Quiros J, Molina E, Huerta JM, Crowe F, Wirfal E, Ericson U, Peeters PH, Kaaks R, Teucher B, Johansson G, Johansson I, Tumino R, Boeing H, Drogan D, Amiano P, Mattiello A, Khaw KT, Luben R, Krogh V, Ardanaz E, Sacerdote C, Salvini S, Overvad K, Tjonneland A, Olsen A, Boutron-Ruault MC, Fagherazzi G, Perquier F, Gonzalez CA (2012) Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Br J Nutr 108:1095–1108. doi:10.​1017/​S000711451100638​6 CrossRef
23.
go back to reference Arts IC, Hollman PC, Feskens EJ, Bueno de Mesquita HB, Kromhout D (2001) Catechin intake and associated dietary and lifestyle factors in a representative sample of Dutch men and women. Eur J Clin Nutr 55:76–81CrossRef Arts IC, Hollman PC, Feskens EJ, Bueno de Mesquita HB, Kromhout D (2001) Catechin intake and associated dietary and lifestyle factors in a representative sample of Dutch men and women. Eur J Clin Nutr 55:76–81CrossRef
24.
go back to reference Bosetti C, Rossi M, McLaughlin JK, Negri E, Talamini R, Lagiou P, Montella M, Ramazzotti V, Franceschi S, LaVecchia C (2007) Flavonoids and the risk of renal cell carcinoma. Cancer Epidemiol Biomarkers Prev 16:98–101. doi:10.1158/1055-9965.EPI-06-0769 CrossRef Bosetti C, Rossi M, McLaughlin JK, Negri E, Talamini R, Lagiou P, Montella M, Ramazzotti V, Franceschi S, LaVecchia C (2007) Flavonoids and the risk of renal cell carcinoma. Cancer Epidemiol Biomarkers Prev 16:98–101. doi:10.​1158/​1055-9965.​EPI-06-0769 CrossRef
25.
go back to reference Johannot L, Somerset SM (2006) Age-related variations in flavonoid intake and sources in the Australian population. Public Health Nutr 9:1045–1054CrossRef Johannot L, Somerset SM (2006) Age-related variations in flavonoid intake and sources in the Australian population. Public Health Nutr 9:1045–1054CrossRef
26.
27.
go back to reference Mursu J, Nurmi T, Tuomainen TP, Salonen JT, Pukkala E, Voutilainen S (2008) Intake of flavonoids and risk of cancer in Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Int J Cancer 123:660–663. doi:10.1002/ijc.23421 CrossRef Mursu J, Nurmi T, Tuomainen TP, Salonen JT, Pukkala E, Voutilainen S (2008) Intake of flavonoids and risk of cancer in Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Int J Cancer 123:660–663. doi:10.​1002/​ijc.​23421 CrossRef
28.
go back to reference Ovaskainen ML, Torronen R, Koponen JM, Sinkko H, Hellstrom J, Reinivuo H, Mattila P (2008) Dietary intake and major food sources of polyphenols in Finnish adults. J Nutr 138:562–566 Ovaskainen ML, Torronen R, Koponen JM, Sinkko H, Hellstrom J, Reinivuo H, Mattila P (2008) Dietary intake and major food sources of polyphenols in Finnish adults. J Nutr 138:562–566
29.
30.
go back to reference Rossi M, Rosato V, Bosetti C, Lagiou P, Parpinel M, Bertuccio P, Negri E, La Vecchia C (2010) Flavonoids, proanthocyanidins, and the risk of stomach cancer. Cancer Causes Control 21:1597–1604. doi:10.1007/s10552-010-9588-4 CrossRef Rossi M, Rosato V, Bosetti C, Lagiou P, Parpinel M, Bertuccio P, Negri E, La Vecchia C (2010) Flavonoids, proanthocyanidins, and the risk of stomach cancer. Cancer Causes Control 21:1597–1604. doi:10.​1007/​s10552-010-9588-4 CrossRef
31.
go back to reference Zamora-Ros R, Andres-Lacueva C, Lamuela-Raventos RM, Berenguer T, Jakszyn P, Barricarte A, Ardanaz E, Amiano P, Dorronsoro M, Larranaga N, Martinez C, Sanchez MJ, Navarro C, Chirlaque MD, Tormo MJ, Quiros JR, Gonzalez CA (2010) Estimation of dietary sources and flavonoid intake in a Spanish adult population (EPIC-Spain). J Am Diet Assoc 110:390–398. doi:10.1016/j.jada.2009.11.024 CrossRef Zamora-Ros R, Andres-Lacueva C, Lamuela-Raventos RM, Berenguer T, Jakszyn P, Barricarte A, Ardanaz E, Amiano P, Dorronsoro M, Larranaga N, Martinez C, Sanchez MJ, Navarro C, Chirlaque MD, Tormo MJ, Quiros JR, Gonzalez CA (2010) Estimation of dietary sources and flavonoid intake in a Spanish adult population (EPIC-Spain). J Am Diet Assoc 110:390–398. doi:10.​1016/​j.​jada.​2009.​11.​024 CrossRef
32.
go back to reference Krems C, Walter C, Heuer T, Hoffmann I (2012) Lebensmittelverzehr und Nährstoffzufuhr—Ergebnisse der Nationalen Verzehrsstudie II (Food consumption and nutrient intake—Results of the German National Nutrition Survey II). In: Deutsche Gesellschaft für Ernährung (Hrsg.). 12. Ernährungsbericht 2012, Bonn Krems C, Walter C, Heuer T, Hoffmann I (2012) Lebensmittelverzehr und Nährstoffzufuhr—Ergebnisse der Nationalen Verzehrsstudie II (Food consumption and nutrient intake—Results of the German National Nutrition Survey II). In: Deutsche Gesellschaft für Ernährung (Hrsg.). 12. Ernährungsbericht 2012, Bonn
33.
go back to reference Chun OK, Chung SJ, Song WO (2007) Estimated dietary flavonoid intake and major food sources of U.S. adults. J Nutr 137:1244–1252 Chun OK, Chung SJ, Song WO (2007) Estimated dietary flavonoid intake and major food sources of U.S. adults. J Nutr 137:1244–1252
35.
go back to reference Song WO, Chun OK (2008) Tea is the major source of flavan-3-ol and flavonol in the U.S. diet. J Nutr 138:1543S–1547S Song WO, Chun OK (2008) Tea is the major source of flavan-3-ol and flavonol in the U.S. diet. J Nutr 138:1543S–1547S
37.
go back to reference Theodoratou E, Kyle J, Cetnarskyj R, Farrington SM, Tenesa A, Barnetson R, Porteous M, Dunlop M, Campbell H (2007) Dietary flavonoids and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 16:684–693. doi:10.1158/1055-9965.EPI-06-0785 CrossRef Theodoratou E, Kyle J, Cetnarskyj R, Farrington SM, Tenesa A, Barnetson R, Porteous M, Dunlop M, Campbell H (2007) Dietary flavonoids and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 16:684–693. doi:10.​1158/​1055-9965.​EPI-06-0785 CrossRef
Metadata
Title
Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II)
Authors
Anna Vogiatzoglou
Thorsten Heuer
Angela A. Mulligan
Marleen A. H. Lentjes
Robert N. Luben
Gunter G. C. Kuhnle
Publication date
01-03-2014
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nutrition / Issue 2/2014
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-013-0572-0

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