Skip to main content
Top
Published in: Clinical Research in Cardiology 5/2020

01-05-2020 | Aortic Valve Replacement | Original Paper

Lower mortality in an all-comers aortic stenosis population treated with TAVI in comparison to SAVR

Authors: Helge Möllmann, Oliver Husser, Johannes Blumenstein, Christoph Liebetrau, Oliver Dörr, Won-Keun Kim, Holger Nef, Christian Tesche, Christian W. Hamm, Albrecht Elsässer, Stephan Achenbach, Luise Gaede

Published in: Clinical Research in Cardiology | Issue 5/2020

Login to get access

Abstract

Background

Within the last years TAVI—especially transfemoral/transvascular TAVI—has proven to be a valuable therapeutic option for most patients suffering from AS. Here, we present the outcome of a complete dataset of all patients undergoing aortic valve replacement in Germany in 2018.

Methods

The data of all aortic valve procedures performed in Germany in 2018 derive from the mandatory nationwide quality control program. Patients were stratified with a new version of the German Aortic valve score (AKL Score) divided in different risk stratification depending on the treatment with either a catheter based (TV-TAVI) or surgical (iSAVR) approach. In-hospital outcomes have been compared between the two approaches.

Results

19,317 transvascular (TV)–TAVI procedures were carried out. In contrast to this steady growth, the number of iSAVR andtransapical (TA) -TAVI procedures declined. In-hospital mortality after TV-TAVI (2.5%) was lower when compared to iSAVR (3.1%) as well as TA-TAVI (5.7%) in-hospital mortality after TV-TAVI was significantly lowest (Fig. 2) with an in-hospital mortality rate of 2.5%. TV-TAVI was the only approach with an observed vs. expected mortality ratio < 1 according to the used risk prediction model.

Conclusion

TV-TAVI is more often performed and shows lower in-hospital mortality than iSAVR. TV-TAVI has replaced iSAVR as the gold-standard concerning in-hospital outcome in aortic stenosis management.
Literature
1.
go back to reference Leon M, Smith C, Mack M, Miller D, Moses J, Svensson L, Tuzcu M, Webb J, Fontana G, Makkar R, Brown D, Block P, Guyton R, Pichard A, Bavaria J, Herrmann H, Douglas P, Peterson J, Akin J, Anderson W, Wand D, Pcocock S for the PTI (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363:1597–1607CrossRef Leon M, Smith C, Mack M, Miller D, Moses J, Svensson L, Tuzcu M, Webb J, Fontana G, Makkar R, Brown D, Block P, Guyton R, Pichard A, Bavaria J, Herrmann H, Douglas P, Peterson J, Akin J, Anderson W, Wand D, Pcocock S for the PTI (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363:1597–1607CrossRef
2.
go back to reference Smith C, Leon M, Mack M, Miller D, Moses J, Svnesson L, Tuzcu E, Webb J, Fontana G, Makkar R, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani V, Corso P, Pichard A, Bavaria J, Herrmann H, Akin J, Anderson W, Wang D, PS for the PTI (2011) Transcatheter versus surgical aotic-valve replacement in high-risk patients. N Engl J Med 364:2187–2198CrossRef Smith C, Leon M, Mack M, Miller D, Moses J, Svnesson L, Tuzcu E, Webb J, Fontana G, Makkar R, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani V, Corso P, Pichard A, Bavaria J, Herrmann H, Akin J, Anderson W, Wang D, PS for the PTI (2011) Transcatheter versus surgical aotic-valve replacement in high-risk patients. N Engl J Med 364:2187–2198CrossRef
8.
go back to reference Bekeredjian R, Szabo G, Balaban Ü et al (2018) Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY). Eur Heart J. https://doi.org/10.1093/eurheartj/ehy699 CrossRef Bekeredjian R, Szabo G, Balaban Ü et al (2018) Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY). Eur Heart J. https://​doi.​org/​10.​1093/​eurheartj/​ehy699 CrossRef
Metadata
Title
Lower mortality in an all-comers aortic stenosis population treated with TAVI in comparison to SAVR
Authors
Helge Möllmann
Oliver Husser
Johannes Blumenstein
Christoph Liebetrau
Oliver Dörr
Won-Keun Kim
Holger Nef
Christian Tesche
Christian W. Hamm
Albrecht Elsässer
Stephan Achenbach
Luise Gaede
Publication date
01-05-2020
Publisher
Springer Berlin Heidelberg
Published in
Clinical Research in Cardiology / Issue 5/2020
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-019-01548-1

Other articles of this Issue 5/2020

Clinical Research in Cardiology 5/2020 Go to the issue