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International Journal of Colorectal Disease

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01-02-2020 | Rectal Cancer | Original Article

Efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after laparoscopic colorectal cancer surgery

Authors: Masayuki Ishii, Atsushi Hamabe, Kenji Okita, Toshihiko Nishidate, Koichi Okuya, Akihiro Usui, Emi Akizuki, Tetsuta Satoyoshi, Ichiro Takemasa

Published in: International Journal of Colorectal Disease | Issue 2/2020

Abstract

Purpose

Some recent studies have suggested that fluorescence angiography with indocyanine green (ICG) might be useful for preventing anastomotic leakage (AL) after laparoscopic colorectal surgery. However, its efficacy has not been proven. We evaluated whether intraoperative ICG fluorescence angiography could decrease the AL rate with laparoscopic colorectal cancer surgery.

Methods

This retrospective study included patients with colorectal cancer who underwent laparoscopic surgery at our institution between March 2014 and December 2018. Patients were divided into two groups: with or without ICG fluorescence angiography. The primary outcome was the rate of AL.

Results

A total of 488 patients were included: 223 patients in the ICG group and 265 patients in the no-ICG group. In the ICG group, the transection line was changed to a more proximal location in seven patients (3.1%), including one patient with transverse colon surgery and six with rectal surgery. None of these seven patients developed AL. There were 18 ALs (3.7%) overall. The AL rate was 1.8% in the ICG group and 5.3% in the no-ICG group. For colon cancer, there were no significant differences in the AL rate between the groups (p = 0.278). In rectal cancer, the AL rate was significantly lower in the ICG group than in the no-ICG group (3.5% vs. 10.5%, p = 0.041). After propensity score matching, the AL rate was also significantly lower in the ICG group for rectal cancer (p = 0.044).

Conclusion

ICG fluorescence angiography can potentially reduce the AL rate with laparoscopic rectal cancer surgery.

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Title: Efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after laparoscopic colorectal cancer surgery
Authors: Masayuki Ishii
Atsushi Hamabe
Kenji Okita
Toshihiko Nishidate
Koichi Okuya
Akihiro Usui
Emi Akizuki
Tetsuta Satoyoshi
Ichiro Takemasa
Publication date: 01-02-2020
Publisher: Springer Berlin Heidelberg
Keywords: Rectal Cancer
Angiography
Rectal Cancer
Colorectal Cancer
Colorectal Cancer
Colon Cancer
Colon Cancer
Published in: International Journal of Colorectal Disease / Issue 2/2020
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-019-03482-0

Keynote webinar | Spotlight on sleep in brain health

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Efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after laparoscopic colorectal cancer surgery

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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