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Child's Nervous System
Published in: Child's Nervous System 5/2017

01-05-2017 | Case Report

Second re-irradiation for DIPG progression, re-considering “old strategies” with new approaches

Authors: Andres Morales La Madrid, Vicente Santa-María, Ofelia Cruz Martinez, Jaume Mora, Patricia Puerta Roldan, Antonio Guillen Quesada, Mariona Suñol Capella, Carmen de Torres Gomez-Pallete, Alvaro Lassaletta, Normand Laperriere, Salvador Villà, Eric Bouffet

Published in: Child's Nervous System | Issue 5/2017

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Abstract

Diffuse intrinsic pontine glioma (DIPG) is an aggressive infiltrative glioma for which no curative therapy is available. Radiation therapy (RT) is the only potentially effective intervention in delaying tumor progression, but only transiently. At progression, re-irradiation is gaining popularity as an effective palliative therapy. However, at second progression, exclusive symptomatic treatment is usually offered. Here we report two patients with DIPG at second progression who were treated with a second re-irradiation course with good response. Importantly, treatment was well tolerated with no irradiation associated acute toxicity identified.
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Metadata
Title
Second re-irradiation for DIPG progression, re-considering “old strategies” with new approaches
Authors
Andres Morales La Madrid
Vicente Santa-María
Ofelia Cruz Martinez
Jaume Mora
Patricia Puerta Roldan
Antonio Guillen Quesada
Mariona Suñol Capella
Carmen de Torres Gomez-Pallete
Alvaro Lassaletta
Normand Laperriere
Salvador Villà
Eric Bouffet
Publication date
01-05-2017
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 5/2017
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-017-3352-y

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