Skip to main content
Top
Published in: Child's Nervous System 2/2017

01-02-2017 | Case Report

Hyper-vascular giant cavernous malformation in a child: a case report and review

Authors: Koji Hirata, Satoshi Ihara, Masayuki Sato, Yuji Matsumaru, Tetsuya Yamamoto

Published in: Child's Nervous System | Issue 2/2017

Login to get access

Abstract

Introduction

Giant cavernous malformation (GCM) in children is a rare vascular anomaly, and its natural history is unclear. Despite their giant size, intraparenchymal GCMs are low-flow vascular malformations. Herein, we report a case of hyper-vascular intraparenchymal GCM with an AV shunt in a child.

Case

A 3-year-old boy had had an enlarged head since infancy. Magnetic resonance (MR) images on admission showed a strikingly enhanced mass lesion, 6 cm in size. A 4-vessel CAG demonstrated a hyper-vascular mass with an AV shunt. After transarterial embolization, the patient underwent total excision of the mass. The tumor bled easily, during surgery the patient lost 400 cm3 in blood. Histopathological examination confirmed the diagnosis of cavernous hemangioma.

Conclusion

The differential diagnosis of intraparenchymal, strikingly-enhanced tumors with an AV shunt include hyper-vascular GCMs. Consideration of potential for bleeding during the operation is also important.
Literature
1.
go back to reference Bradley AG, Ning L, Rose D, Arthur LD (2011) The natural history of intracranial cavernous malformations. Neurosurg Focus 30(6):E24CrossRef Bradley AG, Ning L, Rose D, Arthur LD (2011) The natural history of intracranial cavernous malformations. Neurosurg Focus 30(6):E24CrossRef
2.
go back to reference Kan P, Tubay M, Osborn A, Blaser S, Couldwell WT (2008) Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir 150:49–55CrossRefPubMed Kan P, Tubay M, Osborn A, Blaser S, Couldwell WT (2008) Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir 150:49–55CrossRefPubMed
3.
go back to reference Ozgen B, Senocak E, Oguz KK, Soylemezoglu F, Akalan N (2011) Radiological features of childhood giant cavernous malformations. Neuroradiology 53:283–289CrossRefPubMed Ozgen B, Senocak E, Oguz KK, Soylemezoglu F, Akalan N (2011) Radiological features of childhood giant cavernous malformations. Neuroradiology 53:283–289CrossRefPubMed
4.
go back to reference Yoshimura J, Tsukamoto Y, Sano M, Hasegawa H, Nishino K, Saito A, Fukuda M, Okamoto K, Fujii Y (2014) Successful removal of a huge hyper-vascular tentorial cavernous angioma after preoperative endovascular embolization. J Neurosurg Pediatrics 14:43–47CrossRef Yoshimura J, Tsukamoto Y, Sano M, Hasegawa H, Nishino K, Saito A, Fukuda M, Okamoto K, Fujii Y (2014) Successful removal of a huge hyper-vascular tentorial cavernous angioma after preoperative endovascular embolization. J Neurosurg Pediatrics 14:43–47CrossRef
5.
go back to reference Dashti SR, Fiorella D, Spetzler RF, Beres E, McDougall CG, Albuquerque FC (2009) Preoperative Onyx embolization of a giant cavernous malformation involving the dural sinuses. J Neurosurg Pediatr 3:302–306CrossRefPubMed Dashti SR, Fiorella D, Spetzler RF, Beres E, McDougall CG, Albuquerque FC (2009) Preoperative Onyx embolization of a giant cavernous malformation involving the dural sinuses. J Neurosurg Pediatr 3:302–306CrossRefPubMed
6.
go back to reference Kim YJ, Kim JE, Kim NR, Kim HS (2007) Imaging findings of giant cavernous malformation with a focal infiltrative pattern. Pediatr Radiol 37:1039–1042CrossRefPubMed Kim YJ, Kim JE, Kim NR, Kim HS (2007) Imaging findings of giant cavernous malformation with a focal infiltrative pattern. Pediatr Radiol 37:1039–1042CrossRefPubMed
7.
go back to reference Khosla VK, Banerjee AK, Mathuriya SN, Mehta S (1984) Giant cystic cavernoma in a child. Case report J Neurosurg 60:1297–1299PubMed Khosla VK, Banerjee AK, Mathuriya SN, Mehta S (1984) Giant cystic cavernoma in a child. Case report J Neurosurg 60:1297–1299PubMed
8.
go back to reference Kawagishi J, Suzuki M, Kayama T, Yoshimoto T (1993) Huge multilobular cavernous angioma in an infant: case report. Neurosurgery 32:1028–1031CrossRefPubMed Kawagishi J, Suzuki M, Kayama T, Yoshimoto T (1993) Huge multilobular cavernous angioma in an infant: case report. Neurosurgery 32:1028–1031CrossRefPubMed
9.
go back to reference Alvarez H, Perry V, Solle M, Castillo M (2012) De novo cerebral arteriovenous malformation in a child with previous cavernous malformation and developmental venous anomaly. J Neurosurg Pediatr 9:327–330CrossRefPubMed Alvarez H, Perry V, Solle M, Castillo M (2012) De novo cerebral arteriovenous malformation in a child with previous cavernous malformation and developmental venous anomaly. J Neurosurg Pediatr 9:327–330CrossRefPubMed
10.
go back to reference Hayashi T, Fukui M, Shoyima K, Utsonomiya H, Kawasaki K (1985) Giant cerebellar hemangioma in an infant. Childs Nerv Syst 1:230–233CrossRefPubMed Hayashi T, Fukui M, Shoyima K, Utsonomiya H, Kawasaki K (1985) Giant cerebellar hemangioma in an infant. Childs Nerv Syst 1:230–233CrossRefPubMed
11.
go back to reference Chicani CF, Miller NR, Tamargo RJ (2003) Giant cavernous malformation of the occipital lobe. J Neuroophthalmol 23:151–153CrossRefPubMed Chicani CF, Miller NR, Tamargo RJ (2003) Giant cavernous malformation of the occipital lobe. J Neuroophthalmol 23:151–153CrossRefPubMed
12.
go back to reference Lew SM (2010) Giant posterior fossa cavernous malformations in 2 infants with familial cerebral cavernomatosis: the case for early screening. Neurosurg Focus 29:E18CrossRefPubMed Lew SM (2010) Giant posterior fossa cavernous malformations in 2 infants with familial cerebral cavernomatosis: the case for early screening. Neurosurg Focus 29:E18CrossRefPubMed
13.
go back to reference Lawton MT, Vates GE, Quinones-Hinojosa A, McDonald W, Marchuk D (2004) Giant infiltrative cavernous malformation: clinical presentation, intervention, and genetic analysis: case report. Neurosurgery 55:988–995CrossRef Lawton MT, Vates GE, Quinones-Hinojosa A, McDonald W, Marchuk D (2004) Giant infiltrative cavernous malformation: clinical presentation, intervention, and genetic analysis: case report. Neurosurgery 55:988–995CrossRef
14.
go back to reference Thakar S, Furtado SV, Ghosal N, Hegde AS (2010) A peri-trigonal giant tumefactive cavernous malformation: case report and review of literature. Childs Nerv Syst 26:1819–1823CrossRefPubMed Thakar S, Furtado SV, Ghosal N, Hegde AS (2010) A peri-trigonal giant tumefactive cavernous malformation: case report and review of literature. Childs Nerv Syst 26:1819–1823CrossRefPubMed
15.
go back to reference de Andrade GC, Prandini MN, Brage FM (2002) Giant cavernous angioma: report of two cases. Arq Neuropsiquiatr 60:481–486CrossRefPubMed de Andrade GC, Prandini MN, Brage FM (2002) Giant cavernous angioma: report of two cases. Arq Neuropsiquiatr 60:481–486CrossRefPubMed
16.
go back to reference Avci E, Ozturk A, Baba F, Karabag H, Cakir A (2007) Huge cavernoma with massive intracerebral hemorrhage in a child. Turk Neurosurg 17:23–26PubMed Avci E, Ozturk A, Baba F, Karabag H, Cakir A (2007) Huge cavernoma with massive intracerebral hemorrhage in a child. Turk Neurosurg 17:23–26PubMed
19.
go back to reference Van Lindert EJ, Tan TC, Grotenhuis JA, Wesseling P (2007) Giant cavernous hemangiomas: report of three cases. Neurosurg Rev 30:83–92CrossRefPubMed Van Lindert EJ, Tan TC, Grotenhuis JA, Wesseling P (2007) Giant cavernous hemangiomas: report of three cases. Neurosurg Rev 30:83–92CrossRefPubMed
20.
go back to reference Kasliwal MK, Gupta A, Sharma BS (2010) Rare case of giant temporal cavernous angioma in a child. Pediatr Neurosurg 46:324–325CrossRefPubMed Kasliwal MK, Gupta A, Sharma BS (2010) Rare case of giant temporal cavernous angioma in a child. Pediatr Neurosurg 46:324–325CrossRefPubMed
21.
go back to reference Mohindra S, Sodhi HS, Rane S (2013) Tumefactive presentation of a supratentorial cavernous hemangioma: a report of two cases. J Pediatr Neurosci 8:232–234CrossRefPubMedPubMedCentral Mohindra S, Sodhi HS, Rane S (2013) Tumefactive presentation of a supratentorial cavernous hemangioma: a report of two cases. J Pediatr Neurosci 8:232–234CrossRefPubMedPubMedCentral
22.
go back to reference Maraire JN, Awad IA (1995) Intracranial cavernous malformations: lesion behavior and management strategies. Neurosurgery 37:591–605CrossRefPubMed Maraire JN, Awad IA (1995) Intracranial cavernous malformations: lesion behavior and management strategies. Neurosurgery 37:591–605CrossRefPubMed
Metadata
Title
Hyper-vascular giant cavernous malformation in a child: a case report and review
Authors
Koji Hirata
Satoshi Ihara
Masayuki Sato
Yuji Matsumaru
Tetsuya Yamamoto
Publication date
01-02-2017
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 2/2017
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-016-3234-8

Other articles of this Issue 2/2017

Child's Nervous System 2/2017 Go to the issue