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Published in: Child's Nervous System 8-9/2005

01-08-2005 | Special Annual Issue

Intracavitary therapeutic options in the management of cystic craniopharyngioma

Author: Adrián Cáceres

Published in: Child's Nervous System | Issue 8-9/2005

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Abstract

Background

Craniopharyngioma remains an entity of controversial management due to its critical anatomical relationships and its well-known recurrence tendency. Total resection, although desirable, is not always accomplished, and it is associated with potentially permanent endocrinological and visual deficits. Consequently, this situation has led to the development of new management strategies seeking lesser morbidity. Because a high percentage of these lesions are cystic, bleomycin and radioactive-emitting sources have been postulated as new therapeutic options with promising results.

Discussion

The information known to date regarding these substances is summarized and we perform a retrospective review of the clinical trials conducted over the past 30 years with special emphasis on outcome, morbidity, and mortality. Two cases from our institution are presented as examples of multimodality management.

Conclusion

Overall, these newer options stand out as valid alternatives in the controversial management of these challenging tumors.
Literature
1.
go back to reference Adamson TE, Wiestler OD, Kleihues P, Yasargil MG (1990) Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg 73(1):12–17 Adamson TE, Wiestler OD, Kleihues P, Yasargil MG (1990) Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg 73(1):12–17
2.
go back to reference Alen JF, Boto GR, Lagares A, de la Lama A, Gomez PA, Lobato RD (2002) Intratumoural bleomycin as a treatment for recurrent cystic craniopharyngioma. Case report and review of the literature. Neurocirugia (Astur) 13(6):479–485 Alen JF, Boto GR, Lagares A, de la Lama A, Gomez PA, Lobato RD (2002) Intratumoural bleomycin as a treatment for recurrent cystic craniopharyngioma. Case report and review of the literature. Neurocirugia (Astur) 13(6):479–485
3.
go back to reference Anderson DR, Trobe JD, Taren JA, Gebarski SS (1989) Visual outcome in cystic craniopharyngiomas treated with intracavitary phosphorus-32. Ophthalmology 96(12):1786–1792 Anderson DR, Trobe JD, Taren JA, Gebarski SS (1989) Visual outcome in cystic craniopharyngiomas treated with intracavitary phosphorus-32. Ophthalmology 96(12):1786–1792
4.
go back to reference Backlund EO (1989) Colloidal radioisotopes as part of a multi-modality treatment of craniopharyngiomas. J Neurosurg Sci 33(1):95–97 Backlund EO (1989) Colloidal radioisotopes as part of a multi-modality treatment of craniopharyngiomas. J Neurosurg Sci 33(1):95–97
5.
go back to reference Backlund EO, Axelsson B, Bergstrand CG, Eriksson AL, Noren G, Ribbesjo E, Rahn T, Schnell PO, Tallstedt L, Saaf M et al (1989) Treatment of craniopharyngiomas—the stereotactic approach in a ten to twenty-three years’ perspective. I. Surgical, radiological and ophthalmological aspects. Acta Neurochir (Wien) 99(1–2):11–19 Backlund EO, Axelsson B, Bergstrand CG, Eriksson AL, Noren G, Ribbesjo E, Rahn T, Schnell PO, Tallstedt L, Saaf M et al (1989) Treatment of craniopharyngiomas—the stereotactic approach in a ten to twenty-three years’ perspective. I. Surgical, radiological and ophthalmological aspects. Acta Neurochir (Wien) 99(1–2):11–19
6.
go back to reference Bin-Abbas B, Mawlawi H, Sakati N, Khafaja Y, Chaudhary MA, Al-Ashwal A (2001) Endocrine sequelae of childhood craniopharyngioma. J Pediatr Endocrinol Metab 14(7):869–874 Bin-Abbas B, Mawlawi H, Sakati N, Khafaja Y, Chaudhary MA, Al-Ashwal A (2001) Endocrine sequelae of childhood craniopharyngioma. J Pediatr Endocrinol Metab 14(7):869–874
7.
go back to reference Blackburn TP, Doughty D, Plowman PN (1999) Stereotactic intracavitary therapy of recurrent cystic craniopharyngioma by instillation of 90yttrium. Br J Neurosurg 13(4):359–365 Blackburn TP, Doughty D, Plowman PN (1999) Stereotactic intracavitary therapy of recurrent cystic craniopharyngioma by instillation of 90yttrium. Br J Neurosurg 13(4):359–365
8.
go back to reference Bosch DA, Kindmorsh TH, Larsson ST, Backlund EO (1980) Intraneoplastic administration of Bleomycin in intracerebral gliomas, a pilot study. Acta Neurochir Suppl 30:441–444 Bosch DA, Kindmorsh TH, Larsson ST, Backlund EO (1980) Intraneoplastic administration of Bleomycin in intracerebral gliomas, a pilot study. Acta Neurochir Suppl 30:441–444
9.
go back to reference Broggi G, Franzini A (1996) Bleomycin for cystic craniopharyngioma. J Neurosurg 84(6):1080–1081 Broggi G, Franzini A (1996) Bleomycin for cystic craniopharyngioma. J Neurosurg 84(6):1080–1081
10.
go back to reference Broggi G, Franzini A, Cajola L, Pluchino F (1994) Cell kinetic investigations in craniopharyngioma: preliminary results and considerations. Pediatr Neurosurg 21(Suppl 1):21–23 Broggi G, Franzini A, Cajola L, Pluchino F (1994) Cell kinetic investigations in craniopharyngioma: preliminary results and considerations. Pediatr Neurosurg 21(Suppl 1):21–23
11.
go back to reference Broggi G, Giorgi C, Franzini A, Servello D, Solero CL (1989) Preliminary results of intracavitary treatment of craniopharyngioma with bleomycin. J Neurosurg Sci 33(1):145–148 Broggi G, Giorgi C, Franzini A, Servello D, Solero CL (1989) Preliminary results of intracavitary treatment of craniopharyngioma with bleomycin. J Neurosurg Sci 33(1):145–148
12.
go back to reference Buckell M, Crompton MR, Robertson MC, Barnes GK (1970) Lactate dehydrogenase in cerebral cyst fluids; total activity and isoenzyme distributions as an index of malignancy. J Neurosurg 32(5):545–552 Buckell M, Crompton MR, Robertson MC, Barnes GK (1970) Lactate dehydrogenase in cerebral cyst fluids; total activity and isoenzyme distributions as an index of malignancy. J Neurosurg 32(5):545–552
13.
go back to reference Caldarelli M, Di Rocco C, Papacci F, Colosimo C Jr (1998) Management of recurrent craniopharyngioma. Acta Neurochir (Wien) 140(5):447–454 Caldarelli M, Di Rocco C, Papacci F, Colosimo C Jr (1998) Management of recurrent craniopharyngioma. Acta Neurochir (Wien) 140(5):447–454
14.
go back to reference Cavalheiro S, Sparapani FV, Franco JO, da Silva MC, Braga FM (1996) Use of bleomycin in intratumoral chemotherapy for cystic craniopharyngioma. Case report. J Neurosurg 84(1):124–126 Cavalheiro S, Sparapani FV, Franco JO, da Silva MC, Braga FM (1996) Use of bleomycin in intratumoral chemotherapy for cystic craniopharyngioma. Case report. J Neurosurg 84(1):124–126
15.
go back to reference Dorr RT, Von-Hoff DD (1994) Drug monographs. In: Cancer chemotherapy handbook, 2nd edn. Appleton and Lange, Norwalk, CT, pp 227–236 Dorr RT, Von-Hoff DD (1994) Drug monographs. In: Cancer chemotherapy handbook, 2nd edn. Appleton and Lange, Norwalk, CT, pp 227–236
16.
go back to reference Fahlbusch R, Honegger J, Paulus W, Huk W, Buchfelder M (1999) Surgical treatment of craniopharyngiomas: experience with 168 patients. J Neurosurg 90(2):237–250 Fahlbusch R, Honegger J, Paulus W, Huk W, Buchfelder M (1999) Surgical treatment of craniopharyngiomas: experience with 168 patients. J Neurosurg 90(2):237–250
17.
go back to reference Fisher PG, Jenab J, Goldthwaite PT, Tihan T, Wharam MD, Foer DR, Burger PC (1998) Outcomes and failure patterns in childhood craniopharyngiomas. Childs Nerv Syst 14:558–563 Fisher PG, Jenab J, Goldthwaite PT, Tihan T, Wharam MD, Foer DR, Burger PC (1998) Outcomes and failure patterns in childhood craniopharyngiomas. Childs Nerv Syst 14:558–563
18.
go back to reference Frank F, Fabrizi AP, Frank G, Fioravanti A (1995) Stereotactic management of craniopharyngiomas. Stereotact Funct Neurosurg 65(1–4):176–183 Frank F, Fabrizi AP, Frank G, Fioravanti A (1995) Stereotactic management of craniopharyngiomas. Stereotact Funct Neurosurg 65(1–4):176–183
19.
go back to reference Greenberg SB, Magram G (2000) Magnetic resonance cystography with gadopenetate dimeglumine of a cystic craniopharyngioma in a child—a technical note. Pediatr Radiol 30(2):85–86 Greenberg SB, Magram G (2000) Magnetic resonance cystography with gadopenetate dimeglumine of a cystic craniopharyngioma in a child—a technical note. Pediatr Radiol 30(2):85–86
20.
go back to reference Guevara JA, Bunge HJ, Heinrich JJ, Weller G, Villasante A, Chinela AB (1988) Cystic craniopharyngioma treated by 90yttrium silicate colloid. Acta Neurochir Suppl (Wien) 42:109–112 Guevara JA, Bunge HJ, Heinrich JJ, Weller G, Villasante A, Chinela AB (1988) Cystic craniopharyngioma treated by 90yttrium silicate colloid. Acta Neurochir Suppl (Wien) 42:109–112
21.
go back to reference Hader WJ, Steinbok P, Hukin J, Fryer C (2000) Intratumoral therapy with bleomycin for cystic craniopharyngiomas in children. Pediatr Neurosurg 33(4):211–218 Hader WJ, Steinbok P, Hukin J, Fryer C (2000) Intratumoral therapy with bleomycin for cystic craniopharyngiomas in children. Pediatr Neurosurg 33(4):211–218
22.
go back to reference Haisa T, Ueki K, Yoshida S (1994) Toxic effects of bleomycin on the hypothalamus following its administration into a cystic craniopharyngioma. Br J Neurosurg 8(6):747–750 Haisa T, Ueki K, Yoshida S (1994) Toxic effects of bleomycin on the hypothalamus following its administration into a cystic craniopharyngioma. Br J Neurosurg 8(6):747–750
23.
go back to reference Hall WA, Liu H, Truwit CL (2003) Intraoperative MR-guided instillation of phosphorus-32 for cystic craniopharyngiomas: case report. Technol Cancer Res Treat 2(1):19–24 Hall WA, Liu H, Truwit CL (2003) Intraoperative MR-guided instillation of phosphorus-32 for cystic craniopharyngiomas: case report. Technol Cancer Res Treat 2(1):19–24
24.
go back to reference Hasegawa T, Kondziolka D, Hadjipanayis CG, Lunsford LD (2004) Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation. Neurosurgery 54(4):813–820 Hasegawa T, Kondziolka D, Hadjipanayis CG, Lunsford LD (2004) Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation. Neurosurgery 54(4):813–820
25.
go back to reference Hernandez J, Morel C, Gonzalez A, Garcia S, Hernandez M, Zarate A (2002) Uso de la bleomicina mediante un reservorio local en pacientes con craneofaringiomas quísticos. Med Int Mex 18(6):273–277 Hernandez J, Morel C, Gonzalez A, Garcia S, Hernandez M, Zarate A (2002) Uso de la bleomicina mediante un reservorio local en pacientes con craneofaringiomas quísticos. Med Int Mex 18(6):273–277
26.
go back to reference Hetelekidis S, Barnes PD, Tao ML, Fischer EG, Schneider L, Scott RM, Tarbell NJ (1993) 20-year experience in childhood craniopharyngioma. Int J Radiat Oncol Biol Phys 27(2):189–195 Hetelekidis S, Barnes PD, Tao ML, Fischer EG, Schneider L, Scott RM, Tarbell NJ (1993) 20-year experience in childhood craniopharyngioma. Int J Radiat Oncol Biol Phys 27(2):189–195
27.
go back to reference Hoffman HJ, De Silva M, Humphreys RP, Drake JM, Smith ML, Blaser SI (1992) Aggressive surgical management of craniopharyngiomas in children. J Neurosurg 76(1):47–52 Hoffman HJ, De Silva M, Humphreys RP, Drake JM, Smith ML, Blaser SI (1992) Aggressive surgical management of craniopharyngiomas in children. J Neurosurg 76(1):47–52
28.
go back to reference Huk WJ, Mahlstedt J (1983) Intracystic radiotherapy (90Y) of craniopharyngiomas: CT-guided stereotaxic implantation of indwelling drainage system. Am J Neuroradiol 4(3):803–806 Huk WJ, Mahlstedt J (1983) Intracystic radiotherapy (90Y) of craniopharyngiomas: CT-guided stereotaxic implantation of indwelling drainage system. Am J Neuroradiol 4(3):803–806
29.
go back to reference Ishii K, Sugita K, Kobayashi H, Kamida T, Fujiki M, Izumi T, Mori T (2004) Intracranial ectopic recurrence of craniopharyngioma after Ommaya reservoir implantation. Pediatr Neurosurg 40(5):230–233 Ishii K, Sugita K, Kobayashi H, Kamida T, Fujiki M, Izumi T, Mori T (2004) Intracranial ectopic recurrence of craniopharyngioma after Ommaya reservoir implantation. Pediatr Neurosurg 40(5):230–233
30.
go back to reference Jiang R, Liu Z, Zhu C (2002) Preliminary exploration of the clinical effect of bleomycin on craniopharyngiomas. Stereotact Funct Neurosurg 78(2):84–94 Jiang R, Liu Z, Zhu C (2002) Preliminary exploration of the clinical effect of bleomycin on craniopharyngiomas. Stereotact Funct Neurosurg 78(2):84–94
31.
go back to reference Julow J, Lanyi F, Hajda M, Simkovics M, Arany I, Toth S, Pasztor E (1985) The radiotherapy of cystic craniopharyngioma with intracystic installation of 90Y silicate colloid. Acta Neurochir (Wien) 74(3–4):94–99 Julow J, Lanyi F, Hajda M, Simkovics M, Arany I, Toth S, Pasztor E (1985) The radiotherapy of cystic craniopharyngioma with intracystic installation of 90Y silicate colloid. Acta Neurochir (Wien) 74(3–4):94–99
32.
go back to reference Kalapurakal JA, Goldman S, Hsieh YC, Tomita T, Marymont MH (2003) Clinical outcome in children with craniopharyngioma treated with primary surgery and radiotherapy deferred until relapse. Med Pediatr Oncol 40(4):214–218 Kalapurakal JA, Goldman S, Hsieh YC, Tomita T, Marymont MH (2003) Clinical outcome in children with craniopharyngioma treated with primary surgery and radiotherapy deferred until relapse. Med Pediatr Oncol 40(4):214–218
33.
go back to reference Kobayashi T, Kageyama N, Ohara K (1981) Internal irradiation for cystic craniopharyngioma. J Neurosurg 55(6):896–903 Kobayashi T, Kageyama N, Ohara K (1981) Internal irradiation for cystic craniopharyngioma. J Neurosurg 55(6):896–903
34.
go back to reference Kodama T, Matsukado Y, Uemura S (1981) Intracapsular irradiation therapy of craniopharyngiomas with radioactive gold: indication and follow-up results. Neurol Med-Chir (Tokyo) 21(1):49–58 Kodama T, Matsukado Y, Uemura S (1981) Intracapsular irradiation therapy of craniopharyngiomas with radioactive gold: indication and follow-up results. Neurol Med-Chir (Tokyo) 21(1):49–58
35.
go back to reference Kubo O, Takakura K, Miki Y, Okino T, Kitamura K (1974) Intracystic therapy of bleomycin for craniopharyngioma—effect of bleomycin for cultured craniopharyngioma cells and intracystic concentration of bleomycin (author’s transl). No Shinkei Geka 2(10):683–688 Kubo O, Takakura K, Miki Y, Okino T, Kitamura K (1974) Intracystic therapy of bleomycin for craniopharyngioma—effect of bleomycin for cultured craniopharyngioma cells and intracystic concentration of bleomycin (author’s transl). No Shinkei Geka 2(10):683–688
36.
go back to reference Lange M, Kirsch CM, Steude U, Oeckler R (1995) Intracavitary treatment of intrasellar cystic craniopharyngiomas with 90-yttrium by trans-sphenoidal approach—a technical note. Acta Neurochir (Wien) 135(3–4):206–209 Lange M, Kirsch CM, Steude U, Oeckler R (1995) Intracavitary treatment of intrasellar cystic craniopharyngiomas with 90-yttrium by trans-sphenoidal approach—a technical note. Acta Neurochir (Wien) 135(3–4):206–209
37.
go back to reference Leksell L (1951) The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 102(4):316–319 Leksell L (1951) The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 102(4):316–319
38.
go back to reference Lunsford LD, Pollock BE, Kondziolka DS, Levine G, Flickinger JC (1994) Stereotactic options in the management of craniopharyngioma. Pediatr Neurosurg 21(Suppl 1):90–97 Lunsford LD, Pollock BE, Kondziolka DS, Levine G, Flickinger JC (1994) Stereotactic options in the management of craniopharyngioma. Pediatr Neurosurg 21(Suppl 1):90–97
39.
go back to reference Merchant TE, Kiehna EN, Sanford RA, Mulhern RK, Thompson SJ, Wilson MW, Lustig RH, Kun LE (2002) Craniopharyngioma: the St. Jude Children’s Research Hospital experience 1984–2001. Int J Radiat Oncol Biol Phys 53(3):533–542 Merchant TE, Kiehna EN, Sanford RA, Mulhern RK, Thompson SJ, Wilson MW, Lustig RH, Kun LE (2002) Craniopharyngioma: the St. Jude Children’s Research Hospital experience 1984–2001. Int J Radiat Oncol Biol Phys 53(3):533–542
40.
go back to reference Morantz RA, Kimler BF, Vats TS, Hendrson SD (1983) Bleomycin and brain tumors, a review. J Neuroncol 1:249–255 Morantz RA, Kimler BF, Vats TS, Hendrson SD (1983) Bleomycin and brain tumors, a review. J Neuroncol 1:249–255
41.
go back to reference Mottolese C, Stan H, Hermier M, Berlier P, Convert J, Frappaz D, Lapras C (2001) Intracystic chemotherapy with bleomycin in the treatment of craniopharyngiomas. Childs Nerv Syst 17(12):724–730 Mottolese C, Stan H, Hermier M, Berlier P, Convert J, Frappaz D, Lapras C (2001) Intracystic chemotherapy with bleomycin in the treatment of craniopharyngiomas. Childs Nerv Syst 17(12):724–730
42.
go back to reference Musolino A, Munari C, Blond S, Betti O, Lajat Y, Schaub C, Askienazy S, Chodkiewicz JP (1985) Stereotaxic treatment of expanding cysts in craniopharyngiomas by endocavitary beta-irradiation (Re-186; Au-198; Y-90). Neurochirurgie 31(3):169–178 Musolino A, Munari C, Blond S, Betti O, Lajat Y, Schaub C, Askienazy S, Chodkiewicz JP (1985) Stereotaxic treatment of expanding cysts in craniopharyngiomas by endocavitary beta-irradiation (Re-186; Au-198; Y-90). Neurochirurgie 31(3):169–178
43.
go back to reference Nakazawa S, Ohwaki K, Shimura T, Itoh Y, Yajima K (1981) A new treatment of malignant brain tumor—1. Local injection of bleomycin. No Shinkei Geka 9(13):1487–1493 Nakazawa S, Ohwaki K, Shimura T, Itoh Y, Yajima K (1981) A new treatment of malignant brain tumor—1. Local injection of bleomycin. No Shinkei Geka 9(13):1487–1493
44.
go back to reference Netzeband G, Sturm V, Georgi P (1984) Results of stereotactic intracavitary irradiation of cystic craniopharyngiomas. Comparison of the effects of Yttrium-90 and Rhenium-186. Acta Neurochir Suppl 33:341–344 Netzeband G, Sturm V, Georgi P (1984) Results of stereotactic intracavitary irradiation of cystic craniopharyngiomas. Comparison of the effects of Yttrium-90 and Rhenium-186. Acta Neurochir Suppl 33:341–344
45.
go back to reference Pan DH, Lee LS, Huang CI, Wong TT (1990) Stereotactic internal irradiation for cystic craniopharyngiomas: a 6-year experience. Stereotact Funct Neurosurg 54–55:525–530 Pan DH, Lee LS, Huang CI, Wong TT (1990) Stereotactic internal irradiation for cystic craniopharyngiomas: a 6-year experience. Stereotact Funct Neurosurg 54–55:525–530
46.
go back to reference Park DH, Park JY, Kim JH, Chung YG, Lee HK, Lee KC, Suh JK (2002) Outcome of postoperative intratumoral bleomycin injection for cystic craniopharyngioma. J Korean Med Sci 17(2):254–259 Park DH, Park JY, Kim JH, Chung YG, Lee HK, Lee KC, Suh JK (2002) Outcome of postoperative intratumoral bleomycin injection for cystic craniopharyngioma. J Korean Med Sci 17(2):254–259
47.
go back to reference Perry M (2001) The chemotherapy source book. Lippincott Williams & Wilkins, Philadelphia, pp 237–239 Perry M (2001) The chemotherapy source book. Lippincott Williams & Wilkins, Philadelphia, pp 237–239
48.
go back to reference Pollack IF, Lunsford LD, Slamovits TL, Gumerman LW, Levine G, Robinson AG (1988) Stereotaxic intracavitary irradiation for cystic craniopharyngiomas. J Neurosurg 68(2):227–233 Pollack IF, Lunsford LD, Slamovits TL, Gumerman LW, Levine G, Robinson AG (1988) Stereotaxic intracavitary irradiation for cystic craniopharyngiomas. J Neurosurg 68(2):227–233
49.
go back to reference Pollock BE, Lunsford LD, Kondziolka D, Levine G, Flickinger JC (1995) Phosphorus-32 intracavitary irradiation of cystic craniopharyngiomas: current technique and long-term results. Int J Radiat Oncol Biol Phys 33(2):437–446 Pollock BE, Lunsford LD, Kondziolka D, Levine G, Flickinger JC (1995) Phosphorus-32 intracavitary irradiation of cystic craniopharyngiomas: current technique and long-term results. Int J Radiat Oncol Biol Phys 33(2):437–446
50.
go back to reference Rajan B, Ashley S, Gorman C, Jose CC, Horwich A, Bloom HJ, Marsh H, Brada M (1993) Craniopharyngioma—a long-term results following limited surgery and radiotherapy. Radiother Oncol 26(1):1–10 Rajan B, Ashley S, Gorman C, Jose CC, Horwich A, Bloom HJ, Marsh H, Brada M (1993) Craniopharyngioma—a long-term results following limited surgery and radiotherapy. Radiother Oncol 26(1):1–10
51.
go back to reference Reda WA, Hay AA, Ganz JC (2002) A planned combined stereotactic approach for cystic intracranial tumors. Report of two cases. J Neurosurg 97(5 Suppl):610–612 Reda WA, Hay AA, Ganz JC (2002) A planned combined stereotactic approach for cystic intracranial tumors. Report of two cases. J Neurosurg 97(5 Suppl):610–612
52.
go back to reference Saaf M, Thoren M, Bergstrand CG, Noren G, Rahn T, Tallstedt L, Backlund EO(1989) Treatment of craniopharyngiomas—the stereotactic approach in a ten to twenty-three years’ perspective. II. Psychosocial situation and pituitary function. Acta Neurochir (Wien) 99(3–4):97–103 Saaf M, Thoren M, Bergstrand CG, Noren G, Rahn T, Tallstedt L, Backlund EO(1989) Treatment of craniopharyngiomas—the stereotactic approach in a ten to twenty-three years’ perspective. II. Psychosocial situation and pituitary function. Acta Neurochir (Wien) 99(3–4):97–103
53.
go back to reference Sagoh M, Murakami H, Hirose Y, Mayanagi K (1997) Occlusive cerebrovasculopathy after internal radiation and bleomycin therapy for craniopharyngioma—case report. Neurol Med-Chir (Tokyo) 37(12):920–923 Sagoh M, Murakami H, Hirose Y, Mayanagi K (1997) Occlusive cerebrovasculopathy after internal radiation and bleomycin therapy for craniopharyngioma—case report. Neurol Med-Chir (Tokyo) 37(12):920–923
54.
go back to reference Savas A, Arasil E, Batay F, Selcuki M, Kanpolat Y (1999) Intracavitary chemotherapy of polycystic craniopharyngioma with bleomycin. Acta Neurochir (Wien) 141(5):547–548 Savas A, Arasil E, Batay F, Selcuki M, Kanpolat Y (1999) Intracavitary chemotherapy of polycystic craniopharyngioma with bleomycin. Acta Neurochir (Wien) 141(5):547–548
55.
go back to reference Savas A, Erdem A, Tun K, Kanpolat Y (2000) Fatal toxic effect of bleomycin on brain tissue after intracystic chemotherapy for a craniopharyngioma: case report. Neurosurgery 46(1):213–216 Savas A, Erdem A, Tun K, Kanpolat Y (2000) Fatal toxic effect of bleomycin on brain tissue after intracystic chemotherapy for a craniopharyngioma: case report. Neurosurgery 46(1):213–216
56.
go back to reference Schefter JK, Allen G, Cmelak AJ, Johnson M, Toms S, Duggan D, Blevins LS (2002) The utility of external beam radiation and intracystic 32P radiation in the treatment of craniopharyngiomas. J Neurooncol 56(1):69–78 Schefter JK, Allen G, Cmelak AJ, Johnson M, Toms S, Duggan D, Blevins LS (2002) The utility of external beam radiation and intracystic 32P radiation in the treatment of craniopharyngiomas. J Neurooncol 56(1):69–78
57.
go back to reference Schulz-Ertner D, Frank C, Herfarth KK, Rhein B, Wannenmacher M, Debus J (2002) Fractionated stereotactic radiotherapy for craniopharyngiomas. Int J Radiat Oncol Biol Phys 54(4):1114–1120 Schulz-Ertner D, Frank C, Herfarth KK, Rhein B, Wannenmacher M, Debus J (2002) Fractionated stereotactic radiotherapy for craniopharyngiomas. Int J Radiat Oncol Biol Phys 54(4):1114–1120
58.
go back to reference Scott RM, Hetelekidis S, Barnes PD, Goumnerova L, Tarbell NJ (1994) Surgery, radiation, and combination therapy in the treatment of childhood craniopharyngioma—a 20-year experience. Pediatr Neurosurg 21(Suppl 1):75–81 Scott RM, Hetelekidis S, Barnes PD, Goumnerova L, Tarbell NJ (1994) Surgery, radiation, and combination therapy in the treatment of childhood craniopharyngioma—a 20-year experience. Pediatr Neurosurg 21(Suppl 1):75–81
59.
go back to reference Shapiro B, Fig LM, Gross MD (1999) Intracavitary therapy of craniopharyngiomas. Q J Nucl Med 43(4):367–374 Shapiro B, Fig LM, Gross MD (1999) Intracavitary therapy of craniopharyngiomas. Q J Nucl Med 43(4):367–374
60.
go back to reference Strauss L, Sturm V, Georgi P, Schlegel W, Ostertag H, Clorius JH, van Kaick G (1982) Radioisotope therapy of cystic craniopharyngomas. Int J Radiat Oncol Biol Phys 8(9):1581–1585 Strauss L, Sturm V, Georgi P, Schlegel W, Ostertag H, Clorius JH, van Kaick G (1982) Radioisotope therapy of cystic craniopharyngomas. Int J Radiat Oncol Biol Phys 8(9):1581–1585
61.
go back to reference Sturm V, Rommel T, Strauss L (1981) Preliminary results of intracavitary irradiation of cystic craniopharyngiomas by means of stereotactically applied yttrium-90. In: Schiefer W, Klinger M, Brock M (eds) Advances in neurosurgery 9. Springer, Berlin Heidelberg New York, pp 401–404 Sturm V, Rommel T, Strauss L (1981) Preliminary results of intracavitary irradiation of cystic craniopharyngiomas by means of stereotactically applied yttrium-90. In: Schiefer W, Klinger M, Brock M (eds) Advances in neurosurgery 9. Springer, Berlin Heidelberg New York, pp 401–404
62.
go back to reference Sweet WH (1994) History of surgery for craniopharyngiomas. Pediatr Neurosurg 21(Suppl 1):28–38 Sweet WH (1994) History of surgery for craniopharyngiomas. Pediatr Neurosurg 21(Suppl 1):28–38
63.
go back to reference Szeifert GT, Julow J, Slowik F, Balint K, Lanyi F, Pasztor E (1990) Pathological changes in cystic craniopharyngiomas following intracavital 90yttrium treatment. Acta Neurochir (Wien) 102(1–2):14–18 Szeifert GT, Julow J, Slowik F, Balint K, Lanyi F, Pasztor E (1990) Pathological changes in cystic craniopharyngiomas following intracavital 90yttrium treatment. Acta Neurochir (Wien) 102(1–2):14–18
64.
go back to reference Szikla G, Musolino A, Miyahara S (1984) Colloidal rhenium-186 endocavitary irradiation of cystic craniopharyngiomas and active glioma cysts. Long term results, side effects and clinical dosimetry. Acta Neurochir Suppl 33:331–339 Szikla G, Musolino A, Miyahara S (1984) Colloidal rhenium-186 endocavitary irradiation of cystic craniopharyngiomas and active glioma cysts. Long term results, side effects and clinical dosimetry. Acta Neurochir Suppl 33:331–339
65.
go back to reference Takahashi H, Nakazawa S, Shimura T (1985) Evaluation of postoperative intratumoral injection of bleomycin for craniopharyngioma in children. J Neurosurg 62(1):120–127 Takahashi H, Nakazawa S, Shimura T (1985) Evaluation of postoperative intratumoral injection of bleomycin for craniopharyngioma in children. J Neurosurg 62(1):120–127
66.
go back to reference Takeuchi K (1975) A clinical trial of intravenous bleomycin in the treatment of brain tumors. Int J Clin Pharmacol Biopharm 12(4):419–426 Takeuchi K (1975) A clinical trial of intravenous bleomycin in the treatment of brain tumors. Int J Clin Pharmacol Biopharm 12(4):419–426
67.
go back to reference Takeuchi K (1976) Effect of bleomycin on brain tumors. In: Carter SK, Ichikawa T, Mathe G et al (eds) Fundamental and clinical studies of bleomycin, vol 19. Gann monograph on cancer research. Japan Scientific Societies Press, Tokyo, pp 117–132 Takeuchi K (1976) Effect of bleomycin on brain tumors. In: Carter SK, Ichikawa T, Mathe G et al (eds) Fundamental and clinical studies of bleomycin, vol 19. Gann monograph on cancer research. Japan Scientific Societies Press, Tokyo, pp 117–132
68.
go back to reference Tomita T (1988) Management of craniopharyngiomas in children. Pediatr Neurosci 14(4):204–211 Tomita T (1988) Management of craniopharyngiomas in children. Pediatr Neurosci 14(4):204–211
69.
go back to reference Umezawa H, Maeda K, Takeuchi T, Okami Y (1966) New antibiotics, bleomycin A and B. J Antibiot (Tokyo) 19(5):200–209 Umezawa H, Maeda K, Takeuchi T, Okami Y (1966) New antibiotics, bleomycin A and B. J Antibiot (Tokyo) 19(5):200–209
70.
go back to reference Van den Berge JH, Blaauw G, Breeman WA, Rahmy A, Wijngaarde R (1992) Intracavitary brachytherapy of cystic craniopharyngiomas. J Neurosurg 77(4):545–550 Van den Berge JH, Blaauw G, Breeman WA, Rahmy A, Wijngaarde R (1992) Intracavitary brachytherapy of cystic craniopharyngiomas. J Neurosurg 77(4):545–550
71.
go back to reference Vitaz TW, Hushek S, Shields CB, Moriarty T (2001) Changes in cyst volume following intraoperative MRI-guided Ommaya reservoir placement for cystic craniopharyngioma. Pediatr Neurosurg 35(5):230–234 Vitaz TW, Hushek S, Shields CB, Moriarty T (2001) Changes in cyst volume following intraoperative MRI-guided Ommaya reservoir placement for cystic craniopharyngioma. Pediatr Neurosurg 35(5):230–234
72.
go back to reference Voges J, Sturm V, Lehrke R, Treuer H, Gauss C, Berthold F (1997) Cystic craniopharyngioma: long-term results after intracavitary irradiation with stereotactically applied colloidal beta-emitting radioactive sources. Neurosurgery 40(2):263–269 Voges J, Sturm V, Lehrke R, Treuer H, Gauss C, Berthold F (1997) Cystic craniopharyngioma: long-term results after intracavitary irradiation with stereotactically applied colloidal beta-emitting radioactive sources. Neurosurgery 40(2):263–269
73.
go back to reference Wycis HT, Robbins R, Spiegel M, Meszaros J, Spiegel EA (1954) Studies in stereoencephalotomy. III. Treatment of a cystic craniopharyngioma by injection of radioactive P32. Confin Neurol 14(4):193–202 Wycis HT, Robbins R, Spiegel M, Meszaros J, Spiegel EA (1954) Studies in stereoencephalotomy. III. Treatment of a cystic craniopharyngioma by injection of radioactive P32. Confin Neurol 14(4):193–202
74.
go back to reference Young HF, Fu YS, Fratkin MJ (1976) Organ culture of craniopharyngioma and its cellular effects induced by colloidal chromic phosphate. J Neuropathol Exp Neurol 35(4):404–412 Young HF, Fu YS, Fratkin MJ (1976) Organ culture of craniopharyngioma and its cellular effects induced by colloidal chromic phosphate. J Neuropathol Exp Neurol 35(4):404–412
75.
go back to reference Zanon N (1998) Craniopharyngiomas: intratumoral chemotherapy with bleomycin in children and adolescents. Thesis, Sao Paulo 1997. Arq Neuropsiquiatria 56(4):859–864 Zanon N (1998) Craniopharyngiomas: intratumoral chemotherapy with bleomycin in children and adolescents. Thesis, Sao Paulo 1997. Arq Neuropsiquiatria 56(4):859–864
Metadata
Title
Intracavitary therapeutic options in the management of cystic craniopharyngioma
Author
Adrián Cáceres
Publication date
01-08-2005
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 8-9/2005
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-005-1227-0

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