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Published in: Heart and Vessels 8/2019

01-08-2019 | Acute Coronary Syndrome | Original Article

Assessment of strut coverage of everolimus-eluting platinum chromium stent 2 weeks after implantation by optical coherence tomography

Authors: Norikiyo Oka, Kenichi Fujii, Tadayuki Kadohira, Hideki Kitahara, Yoshihide Fujimoto, Masayuki Takahara, Toshiharu Himi, Keishi Ishikawa, Koichi Sano, Yoshio Kobayashi

Published in: Heart and Vessels | Issue 8/2019

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Abstract

The SYNERGY coronary stent is new-generation drug-eluting stents, which has a thin-strut platinum–chromium platform with everolimus in a biodegradable polymer applied to the abluminal surface. It would be speculated that favorable arterial healing with early strut coverage could be achieved. The present study investigated the degree of strut coverage using optical coherence tomography (OCT) 2 weeks after SYNERGY implantation and clinical factors contributing to strut coverage. A total of 29 patients who underwent staged percutaneous coronary intervention (PCI) to residual lesions 2 weeks after the index PCI with SYNERGY stent implantation were enrolled. At the time of staged PCI, OCT examinations of the SYNERGY stent were performed for conventional OCT analysis on both cross-sectional and strut level. SYNERGY stent showed a high level of strut coverage and apposition, and the percentage was 82.4 ± 12.4% and 96.2 ± 5.0%, respectively. The lesion complexity was significantly related to greater strut coverage on univariate analysis; however, it was found to be insignificant in multivariate analysis. Our findings suggest early arterial healing after SYNERGY stent implantation.
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Metadata
Title
Assessment of strut coverage of everolimus-eluting platinum chromium stent 2 weeks after implantation by optical coherence tomography
Authors
Norikiyo Oka
Kenichi Fujii
Tadayuki Kadohira
Hideki Kitahara
Yoshihide Fujimoto
Masayuki Takahara
Toshiharu Himi
Keishi Ishikawa
Koichi Sano
Yoshio Kobayashi
Publication date
01-08-2019
Publisher
Springer Japan
Published in
Heart and Vessels / Issue 8/2019
Print ISSN: 0910-8327
Electronic ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-019-01360-x

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