Skip to main content
Top
Published in: European Radiology 11/2017

Open Access 01-11-2017 | Urogenital

Size matters: The width and location of a ureteral stone accurately predict the chance of spontaneous passage

Authors: Johan Jendeberg, Håkan Geijer, Muhammed Alshamari, Bartosz Cierzniak, Mats Lidén

Published in: European Radiology | Issue 11/2017

Login to get access

Abstract

Objectives

To determine how to most accurately predict the chance of spontaneous passage of a ureteral stone using information in the diagnostic non-enhanced computed tomography (NECT) and to create predictive models with smaller stone size intervals than previously possible.

Methods

Retrospectively 392 consecutive patients with ureteric stone on NECT were included. Three radiologists independently measured the stone size. Stone location, side, hydronephrosis, CRP, medical expulsion therapy (MET) and all follow-up radiology until stone expulsion or 26 weeks were recorded. Logistic regressions were performed with spontaneous stone passage in 4 weeks and 20 weeks as the dependent variable.

Results

The spontaneous passage rate in 20 weeks was 312 out of 392 stones, 98% in 0–2 mm, 98% in 3 mm, 81% in 4 mm, 65% in 5 mm, 33% in 6 mm and 9% in ≥6.5 mm wide stones.
The stone size and location predicted spontaneous ureteric stone passage. The side and the grade of hydronephrosis only predicted stone passage in specific subgroups.

Conclusion

Spontaneous passage of a ureteral stone can be predicted with high accuracy with the information available in the NECT. We present a prediction method based on stone size and location.

Key Points

Non-enhanced computed tomography can predict the outcome of ureteral stones.
Stone size and location are the most important predictors of spontaneous passage.
Prediction models based on stone width or length and stone location are introduced.
The observed passage rates for stone size in mm-intervals are reported.
Clinicians can make better decisions about treatment.
Literature
1.
go back to reference Scales CD, Saigal CS, Hanley JM et al (2014) The impact of unplanned postprocedure visits in the management of patients with urinary stones. Surgery 155:769–775CrossRef Scales CD, Saigal CS, Hanley JM et al (2014) The impact of unplanned postprocedure visits in the management of patients with urinary stones. Surgery 155:769–775CrossRef
2.
go back to reference Saigal CS, Joyce G, Timilsina AR (2005) Direct and indirect costs of nephrolithiasis in an employed population: opportunity for disease management? Kidney Int 68:1808–1814CrossRef Saigal CS, Joyce G, Timilsina AR (2005) Direct and indirect costs of nephrolithiasis in an employed population: opportunity for disease management? Kidney Int 68:1808–1814CrossRef
3.
go back to reference Sandegård E (1956) Prognosis of stone in the ureter. Acta Chir Scand Suppl 219:1–67PubMed Sandegård E (1956) Prognosis of stone in the ureter. Acta Chir Scand Suppl 219:1–67PubMed
4.
go back to reference Ueno A, Kawamura T, Ogawa A, Takayasu H (1977) Relation of spontaneous passage of ureteral calculi to size. Urology 10:544–546CrossRef Ueno A, Kawamura T, Ogawa A, Takayasu H (1977) Relation of spontaneous passage of ureteral calculi to size. Urology 10:544–546CrossRef
5.
go back to reference Coll DM, Varanelli MJ, Smith RC (2002) Relationship of spontaneous passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT. AJR Am J Roentgenol 178:101–103CrossRef Coll DM, Varanelli MJ, Smith RC (2002) Relationship of spontaneous passage of ureteral calculi to stone size and location as revealed by unenhanced helical CT. AJR Am J Roentgenol 178:101–103CrossRef
6.
go back to reference Preminger GM, Tiselius HG, Assimos DG et al (2007) 2007 Guideline for the management of ureteral calculi. Eur Urol 52:1610–1631CrossRef Preminger GM, Tiselius HG, Assimos DG et al (2007) 2007 Guideline for the management of ureteral calculi. Eur Urol 52:1610–1631CrossRef
7.
go back to reference Kambadakone AR, Eisner BH, Catalano OA, Sahani DV (2010) New and evolving concepts in the imaging and management of urolithiasis: urologists’ perspective. Radiographics 30:603–623CrossRef Kambadakone AR, Eisner BH, Catalano OA, Sahani DV (2010) New and evolving concepts in the imaging and management of urolithiasis: urologists’ perspective. Radiographics 30:603–623CrossRef
8.
9.
go back to reference Ahmed A, Gabr AH, Emara A-A et al (2015) Factors predicting the spontaneous passage of a ureteric calculus of ⩽10mm. Arab J Urol 13:84–90CrossRef Ahmed A, Gabr AH, Emara A-A et al (2015) Factors predicting the spontaneous passage of a ureteric calculus of ⩽10mm. Arab J Urol 13:84–90CrossRef
10.
go back to reference Aldaqadossi HA (2013) Stone expulsion rate of small distal ureteric calculi could be predicted with plasma C-reactive protein. Urolithiasis 41:235–239CrossRef Aldaqadossi HA (2013) Stone expulsion rate of small distal ureteric calculi could be predicted with plasma C-reactive protein. Urolithiasis 41:235–239CrossRef
11.
go back to reference Park CH, Ha JY, Park CH et al (2013) Relationship Between Spontaneous Passage Rates of Ureteral Stones Less Than 8 mm and Serum C-Reactive Protein Levels and Neutrophil Percentages. Korean J Urol 54:615–618CrossRef Park CH, Ha JY, Park CH et al (2013) Relationship Between Spontaneous Passage Rates of Ureteral Stones Less Than 8 mm and Serum C-Reactive Protein Levels and Neutrophil Percentages. Korean J Urol 54:615–618CrossRef
12.
go back to reference Sfoungaristos S, Kavouras A, Perimenis P (2012) Predictors for spontaneous stone passage in patients with renal colic secondary to ureteral calculi. Int Urol Nephrol 44:71–79CrossRef Sfoungaristos S, Kavouras A, Perimenis P (2012) Predictors for spontaneous stone passage in patients with renal colic secondary to ureteral calculi. Int Urol Nephrol 44:71–79CrossRef
13.
go back to reference Liden M, Thunberg P, Broxvall M, Geijer H (2015) Two- and three-dimensional CT measurements of urinary calculi length and width: a comparative study. Acta Radiol 56:487–492CrossRef Liden M, Thunberg P, Broxvall M, Geijer H (2015) Two- and three-dimensional CT measurements of urinary calculi length and width: a comparative study. Acta Radiol 56:487–492CrossRef
15.
go back to reference Eisner BH, Kambadakone A, Monga M et al (2009) Computerized tomography magnified bone windows are superior to standard soft tissue windows for accurate measurement of stone size: an in vitro and clinical study. J Urol 181:1710–1715CrossRef Eisner BH, Kambadakone A, Monga M et al (2009) Computerized tomography magnified bone windows are superior to standard soft tissue windows for accurate measurement of stone size: an in vitro and clinical study. J Urol 181:1710–1715CrossRef
16.
go back to reference Beetz R, Bökenkamp A, Brandis M et al (2001) Diagnosis of congenital dilatation of the urinary tract. Consensus Group of the Pediatric Nephrology Working Society in cooperation with the Pediatric Urology Working Group of the German Society of Urology and with the Pediatric Urology Working Society i. Urologe A 40:495–507, quiz 508–9CrossRef Beetz R, Bökenkamp A, Brandis M et al (2001) Diagnosis of congenital dilatation of the urinary tract. Consensus Group of the Pediatric Nephrology Working Society in cooperation with the Pediatric Urology Working Group of the German Society of Urology and with the Pediatric Urology Working Society i. Urologe A 40:495–507, quiz 508–9CrossRef
17.
go back to reference Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310CrossRef Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310CrossRef
18.
go back to reference Miller OF, Kane CJ (1999) TIime to stone passage for observed ureteral calculi: A guide for patient education. J Urol 162:688–691CrossRef Miller OF, Kane CJ (1999) TIime to stone passage for observed ureteral calculi: A guide for patient education. J Urol 162:688–691CrossRef
19.
go back to reference Lee SR, Jeon HG, Park DS, Choi YD (2012) Longitudinal stone diameter on coronal reconstruction of computed tomography as a predictor of ureteral stone expulsion in medical expulsive therapy. Urology 80:784–789CrossRef Lee SR, Jeon HG, Park DS, Choi YD (2012) Longitudinal stone diameter on coronal reconstruction of computed tomography as a predictor of ureteral stone expulsion in medical expulsive therapy. Urology 80:784–789CrossRef
20.
go back to reference Berkovitz N, Simanovsky N, Katz R et al (2010) Coronal reconstruction of unenhanced abdominal CT for correct ureteral stone size classification. Eur Radiol 20:1047–1051CrossRef Berkovitz N, Simanovsky N, Katz R et al (2010) Coronal reconstruction of unenhanced abdominal CT for correct ureteral stone size classification. Eur Radiol 20:1047–1051CrossRef
21.
go back to reference Nadler RB, Stern JA, Kimm S et al (2004) Coronal imaging to assess urinary tract stone size. J Urol 172:962–964CrossRef Nadler RB, Stern JA, Kimm S et al (2004) Coronal imaging to assess urinary tract stone size. J Urol 172:962–964CrossRef
22.
go back to reference Liden M, Andersson T, Geijer H (2011) Making renal stones change size-impact of CT image post processing and reader variability. Eur Radiol 21:2218–2225CrossRef Liden M, Andersson T, Geijer H (2011) Making renal stones change size-impact of CT image post processing and reader variability. Eur Radiol 21:2218–2225CrossRef
24.
go back to reference Tiselius H (2003) Stone Burden in an Average Swedish Population of Stone Formers Requiring Active Stone Removal: How Can the Stone Size Be Estimated in the Clinical Routine? Eur Urol 43:275–281CrossRef Tiselius H (2003) Stone Burden in an Average Swedish Population of Stone Formers Requiring Active Stone Removal: How Can the Stone Size Be Estimated in the Clinical Routine? Eur Urol 43:275–281CrossRef
25.
go back to reference Pickard R, Starr K, MacLennan G et al (2015) Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. Lancet (London, England) 386:341–349CrossRef Pickard R, Starr K, MacLennan G et al (2015) Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial. Lancet (London, England) 386:341–349CrossRef
26.
go back to reference Choi T, Yoo KH, Choi S-K et al (2015) Analysis of factors affecting spontaneous expulsion of ureteral stones that may predict unfavorable outcomes during watchful waiting periods: What is the influence of diabetes mellitus on the ureter? Korean J Urol 56:455–460CrossRef Choi T, Yoo KH, Choi S-K et al (2015) Analysis of factors affecting spontaneous expulsion of ureteral stones that may predict unfavorable outcomes during watchful waiting periods: What is the influence of diabetes mellitus on the ureter? Korean J Urol 56:455–460CrossRef
28.
go back to reference Seitz C, Liatsikos E, Porpiglia F et al (2009) Medical therapy to facilitate the passage of stones: what is the evidence? Eur Urol 56:455–471CrossRef Seitz C, Liatsikos E, Porpiglia F et al (2009) Medical therapy to facilitate the passage of stones: what is the evidence? Eur Urol 56:455–471CrossRef
29.
go back to reference Demehri S, Steigner ML, Sodickson AD et al (2012) CT-based determination of maximum ureteral stone area: a predictor of spontaneous passage. AJR Am J Roentgenol 198:603–608CrossRef Demehri S, Steigner ML, Sodickson AD et al (2012) CT-based determination of maximum ureteral stone area: a predictor of spontaneous passage. AJR Am J Roentgenol 198:603–608CrossRef
30.
go back to reference Patel SR, Stanton P, Zelinski N et al (2011) Automated renal stone volume measurement by noncontrast computerized tomography is more reproducible than manual linear size measurement. J Urol 186:2275–2279CrossRef Patel SR, Stanton P, Zelinski N et al (2011) Automated renal stone volume measurement by noncontrast computerized tomography is more reproducible than manual linear size measurement. J Urol 186:2275–2279CrossRef
31.
go back to reference Liden M, Andersson T, Broxvall M et al (2012) Urinary stone size estimation: a new segmentation algorithm-based CT method. Eur Radiol 22:731–737CrossRef Liden M, Andersson T, Broxvall M et al (2012) Urinary stone size estimation: a new segmentation algorithm-based CT method. Eur Radiol 22:731–737CrossRef
Metadata
Title
Size matters: The width and location of a ureteral stone accurately predict the chance of spontaneous passage
Authors
Johan Jendeberg
Håkan Geijer
Muhammed Alshamari
Bartosz Cierzniak
Mats Lidén
Publication date
01-11-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 11/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-4852-6

Other articles of this Issue 11/2017

European Radiology 11/2017 Go to the issue