Published in:
01-06-2017 | Magnetic Resonance
Whole-body MRI in patients with Non-bacterial Osteitis: Radiological findings and correlation with clinical data
Published in: European Radiology | Issue 6/2017
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Objectives
To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI.
Methods and materials
In a prospective study, 40 patients with diagnosis of NBO underwent clinical examination and WB-MRI in which STIR- and T1- weighted images were assessed for NBO-typical lesions. Parameters of interest for RINBO were: number of radiologically active lesions (RAL), size of the patients’ maximum RAL presence of extramedullary and spinal involvement. Results were tested for statistical agreement of clinical and MR-based lesion detection. RINBO was tested for correlation with clinical activity.
Results
62/95 clinically/radiologically active lesions were found in 30/33 patients. In 45 % of the cohort, more active lesions were detected by WB-MRI than by clinical examination. RINBO was a significant predictor for the presence of clinically active lesions.
Conclusion
WB-MRI is a powerful diagnostic tool for patients with NBO which can reveal asymptomatic disease activity. With RINBO a standardized evaluation approach is proposed which helps assessing radiologic disease burden and predicts clinical disease activity.
Key Points
• Whole body MRI is a powerful diagnostic tool for patients with non-bacterial Osteitis.
• Whole body MRI can reveal asymptomatic disease activity.
• The radiologic index RINBO offers a standardized evaluation approach.