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Published in: European Radiology 6/2016

01-06-2016 | Gastrointestinal

Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review

Authors: Muhammed Alshamari, Eva Norrman, Mats Geijer, Kjell Jansson, Håkan Geijer

Published in: European Radiology | Issue 6/2016

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Abstract

Objectives

Abdominal radiography is frequently used in acute abdominal non-traumatic pain despite the availability of more advanced diagnostic modalities. This study evaluates the diagnostic accuracy of low-dose CT compared with abdominal radiography, at similar radiation dose levels.

Methods

Fifty-eight patients were imaged with both methods and were reviewed independently by three radiologists. The reference standard was obtained from the diagnosis in medical records. Sensitivity and specificity were calculated. A systematic review was performed after a literature search, finding a total of six relevant studies including the present.

Results

Overall sensitivity with 95 % CI for CT was 75 % (66–83 %) and 46 % (37–56 %) for radiography. Specificity was 87 % (77–94 %) for both methods. In the systematic review the overall sensitivity for CT varied between 75 and 96 % with specificity from 83 to 95 % while the overall sensitivity for abdominal radiography varied between 30 and 77 % with specificity 75 to 88 %.

Conclusions

Based on the current study and available evidence, low-dose CT has higher diagnostic accuracy than abdominal radiography and it should, where logistically possible, replace abdominal radiography in the workup of adult patients with acute non-traumatic abdominal pain.

Key Points

• Low-dose CT has a higher diagnostic accuracy than radiography.
• A systematic review shows that CT has better diagnostic accuracy than radiography.
• Radiography has no place in the workup of acute non-traumatic abdominal pain.
Literature
1.
go back to reference Taourel P, Kessler N, Lesnik A, Blayac PM, Morcos L, Bruel JM (2002) Non-traumatic abdominal emergencies: imaging of acute intestinal obstruction. Eur Radiol 12:2151–2160CrossRefPubMed Taourel P, Kessler N, Lesnik A, Blayac PM, Morcos L, Bruel JM (2002) Non-traumatic abdominal emergencies: imaging of acute intestinal obstruction. Eur Radiol 12:2151–2160CrossRefPubMed
2.
3.
go back to reference Smith-Bindman R, Lipson J, Marcus R et al (2009) Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 169:2078–2086CrossRefPubMedPubMedCentral Smith-Bindman R, Lipson J, Marcus R et al (2009) Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 169:2078–2086CrossRefPubMedPubMedCentral
4.
5.
go back to reference Leitz W, Almén A (2010) 2010:14 Patient doses from X-ray examinations in Sweden - Development 2005–2008 [Report in Swedish] Swedish Radiation Safety Authority, Stockholm Leitz W, Almén A (2010) 2010:14 Patient doses from X-ray examinations in Sweden - Development 2005–2008 [Report in Swedish] Swedish Radiation Safety Authority, Stockholm
6.
go back to reference Hart D, Hillier M, Shrimpton PC (2012) Doses to patients from radiographic and fluoroscopic X-ray imaging procedures in the UK – 2010 Review. The Health Protection Agency (HPA), Centre for radiation, chemical and environmental hazards (CRCE) Hart D, Hillier M, Shrimpton PC (2012) Doses to patients from radiographic and fluoroscopic X-ray imaging procedures in the UK – 2010 Review. The Health Protection Agency (HPA), Centre for radiation, chemical and environmental hazards (CRCE)
8.
go back to reference McCollough CH, Chen GH, Kalender W et al (2012) Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CT. Radiology 264:567–580CrossRefPubMedPubMedCentral McCollough CH, Chen GH, Kalender W et al (2012) Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CT. Radiology 264:567–580CrossRefPubMedPubMedCentral
9.
go back to reference McNitt-Gray MF (2002) AAPM/RSNA physics tutorial for residents: topics in CT. Radiation dose in CT. Radiographics 22:1541–1553CrossRefPubMed McNitt-Gray MF (2002) AAPM/RSNA physics tutorial for residents: topics in CT. Radiation dose in CT. Radiographics 22:1541–1553CrossRefPubMed
10.
go back to reference (2007) The 2007 recommendations of the international commission on radiological protection. ICRP publication 103. Ann ICRP 37:1–332 (2007) The 2007 recommendations of the international commission on radiological protection. ICRP publication 103. Ann ICRP 37:1–332
11.
go back to reference Whiting PF, Rutjes AW, Westwood ME et al (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRefPubMed Whiting PF, Rutjes AW, Westwood ME et al (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRefPubMed
12.
go back to reference Nguyen LK, Wong DD, Fatovich DM et al (2012) Low-dose computed tomography versus plain abdominal radiography in the investigation of an acute abdomen. ANZ J Surg 82:36–41CrossRefPubMed Nguyen LK, Wong DD, Fatovich DM et al (2012) Low-dose computed tomography versus plain abdominal radiography in the investigation of an acute abdomen. ANZ J Surg 82:36–41CrossRefPubMed
13.
go back to reference Lappas JC, Reyes BL, Maglinte DD (2001) Abdominal radiography findings in small-bowel obstruction: relevance to triage for additional diagnostic imaging. AJR Am J Roentgenol 176:167–174CrossRefPubMed Lappas JC, Reyes BL, Maglinte DD (2001) Abdominal radiography findings in small-bowel obstruction: relevance to triage for additional diagnostic imaging. AJR Am J Roentgenol 176:167–174CrossRefPubMed
14.
go back to reference Maglinte DD, Reyes BL, Harmon BH et al (1996) Reliability and role of plain film radiography and CT in the diagnosis of small-bowel obstruction. AJR Am J Roentgenol 167:1451–1455CrossRefPubMed Maglinte DD, Reyes BL, Harmon BH et al (1996) Reliability and role of plain film radiography and CT in the diagnosis of small-bowel obstruction. AJR Am J Roentgenol 167:1451–1455CrossRefPubMed
15.
go back to reference Gans SL, Stoker J, Boermeester MA (2012) Plain abdominal radiography in acute abdominal pain; past, present, and future. Int J Gen Med 5:525–533PubMedPubMedCentral Gans SL, Stoker J, Boermeester MA (2012) Plain abdominal radiography in acute abdominal pain; past, present, and future. Int J Gen Med 5:525–533PubMedPubMedCentral
16.
go back to reference van Randen A, Lameris W, Luitse JS et al (2011) The role of plain radiographs in patients with acute abdominal pain at the ED. Am J Emerg Med 29:e582CrossRef van Randen A, Lameris W, Luitse JS et al (2011) The role of plain radiographs in patients with acute abdominal pain at the ED. Am J Emerg Med 29:e582CrossRef
17.
go back to reference MacKersie AB, Lane MJ, Gerhardt RT et al (2005) Nontraumatic acute abdominal pain: unenhanced helical CT compared with three-view acute abdominal series. Radiology 237:114–122CrossRefPubMed MacKersie AB, Lane MJ, Gerhardt RT et al (2005) Nontraumatic acute abdominal pain: unenhanced helical CT compared with three-view acute abdominal series. Radiology 237:114–122CrossRefPubMed
18.
go back to reference Ahn SH, Mayo-Smith WW, Murphy BL, Reinert SE, Cronan JJ (2002) Acute nontraumatic abdominal pain in adult patients: abdominal radiography compared with CT evaluation. Radiology 225:159–164CrossRefPubMed Ahn SH, Mayo-Smith WW, Murphy BL, Reinert SE, Cronan JJ (2002) Acute nontraumatic abdominal pain in adult patients: abdominal radiography compared with CT evaluation. Radiology 225:159–164CrossRefPubMed
19.
go back to reference Haller O, Karlsson L, Nyman R (2010) Can low-dose abdominal CT replace abdominal plain film in evaluation of acute abdominal pain? Ups J Med Sci 115:113–120CrossRefPubMedPubMedCentral Haller O, Karlsson L, Nyman R (2010) Can low-dose abdominal CT replace abdominal plain film in evaluation of acute abdominal pain? Ups J Med Sci 115:113–120CrossRefPubMedPubMedCentral
20.
go back to reference Lehtimaki T, Juvonen P, Valtonen H, Miettinen P, Paajanen H, Vanninen R (2013) Impact of routine contrast-enhanced CT on costs and use of hospital resources in patients with acute abdomen. Results of a randomised clinical trial. Eur Radiol 23:2538–2545CrossRefPubMed Lehtimaki T, Juvonen P, Valtonen H, Miettinen P, Paajanen H, Vanninen R (2013) Impact of routine contrast-enhanced CT on costs and use of hospital resources in patients with acute abdomen. Results of a randomised clinical trial. Eur Radiol 23:2538–2545CrossRefPubMed
21.
go back to reference Keyzer C, Tack D, de Maertelaer V, Bohy P, Gevenois PA, Van Gansbeke D (2004) Acute appendicitis: comparison of low-dose and standard-dose unenhanced multi-detector row CT. Radiology 232:164–172CrossRefPubMed Keyzer C, Tack D, de Maertelaer V, Bohy P, Gevenois PA, Van Gansbeke D (2004) Acute appendicitis: comparison of low-dose and standard-dose unenhanced multi-detector row CT. Radiology 232:164–172CrossRefPubMed
22.
go back to reference Kim SH, Yoon JH, Lee JH et al (2015) Low-dose CT for patients with clinically suspected acute appendicitis: optimal strength of sinogram affirmed iterative reconstruction for image quality and diagnostic performance. Acta Radiol 56:899–907CrossRefPubMed Kim SH, Yoon JH, Lee JH et al (2015) Low-dose CT for patients with clinically suspected acute appendicitis: optimal strength of sinogram affirmed iterative reconstruction for image quality and diagnostic performance. Acta Radiol 56:899–907CrossRefPubMed
23.
go back to reference Hoffstetter P, Schleder S, Jung EM et al (2011) Plain abdominal radiograph - is there any additional clinical value based on the supine projection? Dtsch Med Wochenschr 136:2589–2593CrossRefPubMed Hoffstetter P, Schleder S, Jung EM et al (2011) Plain abdominal radiograph - is there any additional clinical value based on the supine projection? Dtsch Med Wochenschr 136:2589–2593CrossRefPubMed
24.
go back to reference Mangini M, Carrafiello G, Lagana D et al (2008) Non-traumatic acute bowel disease: differential diagnosis with 64-row MDCT. Emerg Radiol 15:171–178CrossRefPubMed Mangini M, Carrafiello G, Lagana D et al (2008) Non-traumatic acute bowel disease: differential diagnosis with 64-row MDCT. Emerg Radiol 15:171–178CrossRefPubMed
25.
go back to reference Schindera ST, Odedra D, Raza SA et al (2013) Iterative reconstruction algorithm for CT: can radiation dose be decreased while low-contrast detectability is preserved? Radiology 269:511–518CrossRefPubMed Schindera ST, Odedra D, Raza SA et al (2013) Iterative reconstruction algorithm for CT: can radiation dose be decreased while low-contrast detectability is preserved? Radiology 269:511–518CrossRefPubMed
Metadata
Title
Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review
Authors
Muhammed Alshamari
Eva Norrman
Mats Geijer
Kjell Jansson
Håkan Geijer
Publication date
01-06-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 6/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-3984-9

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