Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
European Radiology
Published in: European Radiology 4/2016

01-04-2016 | Urogenital

Tubulocystic renal cell carcinoma: a new radiological entity

Authors: F. Cornelis, O. Hélénon, J. M. Correas, L. Lemaitre, M. André, J. Y. Meuwly, C. Sengel, L. Derchi, M. Yacoub, V. Verkarre, N. Grenier

Published in: European Radiology | Issue 4/2016

Login to get access

Abstract

Tubulocystic renal cell carcinoma (TC-RCC) is a recently identified renal malignancy. While approximately 100 cases of TC-RCC have been reported in the pathology literature, imaging features have not yet been clearly described. The purpose of this review is to describe the main radiologic features of this rare sub-type of RCC on ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective HIPAA-compliant review of pathology and imaging databases. Using a combination of sonographic and CT/MRI features, diagnosis of TC-RCC appeared to be strongly suggested in many cases.

Key Points

• Tubulocystic renal cell carcinoma is a new entity with typical imaging features
• Diagnosis of tubulocystic renal cell carcinoma can be suggested preoperatively by imaging
• Cystic renal lesions with high echogenicity may correspond to tubulocystic carcinoma
Literature
1.
Fujii Y, Komai Y, Saito K et al (2008) Incidence of benign pathologic lesions at partial nephrectomy for presumed RCC renal masses: Japanese dual-center experience with 176 consecutive patients. Urology 72:598–602CrossRefPubMed
2.
Scoll BJ, Wong YN, Egleston BL, Kunkle DA, Saad IR, Uzzo RG (2009) Age, tumor size and relative survival of patients with localized renal cell carcinoma: a surveillance, epidemiology and end results analysis. J Urol 181:506–511CrossRefPubMedPubMedCentral
3.
Lechevallier E, Andre M, Barriol D et al (2000) Fine-needle percutaneous biopsy of renal masses with helical CT guidance. Radiology 216:506–510CrossRefPubMed
4.
Cornelis F, Tricaud E, Lasserre AS et al (2014) Routinely performed multiparametric magnetic resonance imaging helps to differentiate common subtypes of renal tumours. Eur Radiol 24:1068–1080CrossRefPubMed
5.
Bosniak MA (1997) Diagnosis and management of patients with complicated cystic lesions of the kidney. Ajr 169:819–821CrossRefPubMed
6.
Smith AD, Remer EM, Cox KL et al (2012) Bosniak category IIF and III cystic renal lesions: outcomes and associations. Radiology 262:152–160CrossRefPubMed
7.
Azoulay S, Vieillefond A, Paraf F et al (2007) Tubulocystic carcinoma of the kidney: a new entity among renal tumors. Virchows Arch 451:905–909CrossRefPubMed
8.
MacLennan GT, Bostwick DG (2005) Tubulocystic carcinoma, mucinous tubular and spindle cell carcinoma, and other recently described rare renal tumors. Clin Lab Med 25:393–416CrossRefPubMed
9.
Osunkoya AO, Young AN, Wang W, Netto GJ, Epstein JI (2009) Comparison of gene expression profiles in tubulocystic carcinoma and collecting duct carcinoma of the kidney. Am J Surg Pathol 33:1103–1106CrossRefPubMed
10.
Amin MB, MacLennan GT, Gupta R et al (2009) Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma. Am J Surg Pathol 33:384–392CrossRefPubMed
11.
Delahunt B, Srigley JR, Montironi R, Egevad L (2014) Advances in renal neoplasia: recommendations from the 2012 International Society of Urological Pathology Consensus Conference. Urology 83:969–974CrossRefPubMed
12.
Kuroda N, Matsumoto H, Ohe C et al (2013) Review of tubulocystic carcinoma of the kidney with focus on clinical and pathobiological aspects. Polish journal of pathology : official journal of the Polish Society of Pathologists 64:233–237CrossRef
13.
Bhullar JS, Varshney N, Bhullar AK, Mittal VK (2013) A new type of renal cancer-tubulocystic carcinoma of the kidney: a review of the literature. Int J Surg Pathol 22:297–302CrossRefPubMed
14.
Zhou M, Yang XJ, Lopez JI et al (2009) Renal tubulocystic carcinoma is closely related to papillary renal cell carcinoma: implications for pathologic classification. Am J Surg Pathol 33:1840–1849CrossRefPubMed
15.
Yang XJ, Zhou M, Hes O et al (2008) Tubulocystic carcinoma of the kidney: clinicopathologic and molecular characterization. Am J Surg Pathol 32:177–187CrossRefPubMed
16.
Srigley JR, Delahunt B (2009) Uncommon and recently described renal carcinomas. Mod Pathol 22:S2–S23CrossRefPubMed
17.
18.
Siegel CL, Middleton WD, Teefey SA, McClennan BL (1996) Angiomyolipoma and renal cell carcinoma: US differentiation. Radiology 198:789–793CrossRefPubMed
19.
Helenon O, Merran S, Paraf F et al (1997) Unusual fat-containing tumors of the kidney: a diagnostic dilemma. Radiographics 17:129–144CrossRefPubMed
20.
Hora M, Urge T, Eret V et al (2011) Tubulocystic renal carcinoma: a clinical perspective. World J Urol 29:349–354CrossRefPubMed
21.
Bluth EI, Bush WH Jr, Amis ES Jr et al (2000) Indeterminate renal masses. American College of Radiology. ACR Appropriateness Criteria. Radiology 215:747–752CrossRefPubMed
22.
Hora M, Hes O, Michal M et al (2005) Extensively cystic renal neoplasms in adults (Bosniak classification II or III)--possible "common" histological diagnoses: multilocular cystic renal cell carcinoma, cystic nephroma, and mixed epithelial and stromal tumor of the kidney. Int Urol Nephrol 37:743–750CrossRefPubMed
Metadata
Title
Tubulocystic renal cell carcinoma: a new radiological entity
Authors
F. Cornelis
O. Hélénon
J. M. Correas
L. Lemaitre
M. André
J. Y. Meuwly
C. Sengel
L. Derchi
M. Yacoub
V. Verkarre
N. Grenier
Publication date
01-04-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 4/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-3923-9

Other articles of this Issue 4/2016

European Radiology 4/2016 Go to the issue

Cardiac

Editorial to: Baseline MDCT findings after prosthetic heart valve implantation provide important complementary information to echocardiography for follow-up purposes by Suchá et al

Musculoskeletal

Prevalence of degenerative and spondyloarthritis-related magnetic resonance imaging findings in the spine and sacroiliac joints in patients with persistent low back pain

Paediatric

Contrast-enhanced MRI of the knee in children unaffected by clinical arthritis compared to clinically active juvenile idiopathic arthritis patients

Neuro

Early post-operative magnetic resonance imaging in glioblastoma: correlation among radiological findings and overall survival in 60 patients

Magnetic Resonance

Thoracic and abdominal aortic diameters in a general population: MRI-based reference values and association with age and cardiovascular risk factors

Computed Tomography

Clinical indications and radiation doses to the conceptus associated with CT imaging in pregnancy: a retrospective study