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01-07-2003 | Breast

Follow-up of women with breast cancer: comparison between MRI and FDG PET

Authors: Gerhard W. Goerres, Sven C. A. Michel, Mathias K. Fehr, Achim H. Kaim, Hans C. Steinert, Burkhardt Seifert, Gustav K. von Schulthess, Rahel A. Kubik-Huch

Published in: European Radiology | Issue 7/2003

Abstract.

The aim of this study was to compare MRI of the breast with ¹⁸F-fluoro-deoxy-glucose (FDG) positron emission tomography (PET) in patients with suspected local or regional breast cancer recurrence or suspected contralateral breast cancer. Thirty-two patients (mean age 57.2 years, age range 32–76 years) with suspected loco-regional recurrence (n=19), chest wall recurrence (n=5), and suspected secondary tumor of the contralateral breast (n=8) underwent MRI of the breast and FDG PET of the whole body and breast region. Cytology/histology (n=17) or a clinical follow-up examination (n=15) with additional imaging served as the standard of reference. A McNemar test was performed to compare PET and MRI, and kappa was determined to quantify agreement of both methods. Sensitivity was 79 and 100%, specificity was 94 and 72%, and accuracy was 88 and 84% for MRI and PET, respectively. Additional metastases outside the field of view of MRI were found in PET in 5 patients. In this study both imaging methods had comparable accuracy. The detection of distant metastases with whole-body PET imaging can influence patient management.

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Title: Follow-up of women with breast cancer: comparison between MRI and FDG PET
Authors: Gerhard W. Goerres
Sven C. A. Michel
Mathias K. Fehr
Achim H. Kaim
Hans C. Steinert
Burkhardt Seifert
Gustav K. von Schulthess
Rahel A. Kubik-Huch
Publication date: 01-07-2003
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 7/2003
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-002-1720-8

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Follow-up of women with breast cancer: comparison between MRI and FDG PET

Abstract.

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