Skip to main content
Top
Published in: Rheumatology International 1/2020

01-01-2020 | Uveitis | Observational Research

Ultrasonographic assessment of femoral cartilage thickness in patients with and without uveitis in Behçet’s disease

Authors: Emre Ata, Murat Kosem, Tugba Ozsoy-Unubol

Published in: Rheumatology International | Issue 1/2020

Login to get access

Abstract

The objective for this study is to evaluate the femoral cartilage thickness in patients with/without uveitis in Behçet’s disease (BD). Patients with BD aged 18–70 years were included. The demographic and clinical characteristics of the patients were recorded. The thickness of femoral articular cartilage was measured with musculoskeletal ultrasound. Cartilage thickness was measured bilaterally from the central points of medial condyle (MFC), lateral condyle (LFC), and intercondylar area (ICA). 20 patients with uveitis [uveitis (+)] and 20 patients without uveitis [uveitis (−)] were included. Both right and left MFC and LFC had statistically significant thinner cartilage in uveitis (+) group (p < 0.05). For the ICA, uveitis (+) patients had thinner femoral cartilage than uveitis (−) patients; however, in the left side, statistically significance could not be detected. Femoral cartilage was thinner in uveitis (+) patients than in uveitis (−) patients in BD. This relationship between uveitis and femoral cartilage thickness may be helpful in the prevention and early treatment of cartilage degeneration.
Literature
1.
go back to reference Gül A (2015) Pathogenesis of Behçet’s disese: autoinflammatory features and beyond. Semin Immunopathol 37(4):413–418CrossRef Gül A (2015) Pathogenesis of Behçet’s disese: autoinflammatory features and beyond. Semin Immunopathol 37(4):413–418CrossRef
2.
go back to reference Mat MC, Sevim A, Fresko İ, Tüzün Y (2014) Behçet’s disease as a systemic disease. Clin Dermatol 32(3):435–442CrossRef Mat MC, Sevim A, Fresko İ, Tüzün Y (2014) Behçet’s disease as a systemic disease. Clin Dermatol 32(3):435–442CrossRef
3.
go back to reference Fresko ISN, Tascilar K (2013) Behçet’s syndrome, polychondritis and eye symptoms in rheumatic diseases. EULAR textbook on rheumatic diseases. BMJ Publishing Group Ltd, London Fresko ISN, Tascilar K (2013) Behçet’s syndrome, polychondritis and eye symptoms in rheumatic diseases. EULAR textbook on rheumatic diseases. BMJ Publishing Group Ltd, London
4.
go back to reference Zierhut M, Abu El-Asrar AM, Bodaghi B, Tugal-Tutkun I (2014) Therapy of ocular Behçet disease. Ocul Immunol Inflamm 22(1):64–76CrossRef Zierhut M, Abu El-Asrar AM, Bodaghi B, Tugal-Tutkun I (2014) Therapy of ocular Behçet disease. Ocul Immunol Inflamm 22(1):64–76CrossRef
5.
go back to reference Evereklioglu C (2004) Managing the symptoms of Behçet’s disease. Expert Opin Pharmacother 5(2):317–328CrossRef Evereklioglu C (2004) Managing the symptoms of Behçet’s disease. Expert Opin Pharmacother 5(2):317–328CrossRef
6.
go back to reference Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P (2016) Behçet’s disease physiopathology: a contemporary review. Auto Immun Highlights 7(1):4CrossRef Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P (2016) Behçet’s disease physiopathology: a contemporary review. Auto Immun Highlights 7(1):4CrossRef
7.
go back to reference Sifuentes Giraldo WA, Guillén Astete CA, Murillo Romero C, Amil Casas I, Rodríguez García AM, Bachiller Corral FJ (2014) Refractory pseudoseptic arthritis in Behçet’s disease successfully treated with infliximab: a case report and literature review. Mod Rheumatol 24(1):199–205CrossRef Sifuentes Giraldo WA, Guillén Astete CA, Murillo Romero C, Amil Casas I, Rodríguez García AM, Bachiller Corral FJ (2014) Refractory pseudoseptic arthritis in Behçet’s disease successfully treated with infliximab: a case report and literature review. Mod Rheumatol 24(1):199–205CrossRef
8.
go back to reference Criteria for diagnosis of Behcet’s disease (1990) International study group for Behcet’s disease. Lancet 335(8697):1078–1080 Criteria for diagnosis of Behcet’s disease (1990) International study group for Behcet’s disease. Lancet 335(8697):1078–1080
9.
go back to reference Suzuki Kurokawa M, Suzuki N (2004) Behcet’s disease. Clin Exp Med 4(1):10–20CrossRef Suzuki Kurokawa M, Suzuki N (2004) Behcet’s disease. Clin Exp Med 4(1):10–20CrossRef
14.
go back to reference Buckwalter JA, Mankin HJ, Grodzinsky AJ (2005) Articular cartilage and osteoarthritis. Instr Course Lect 54:465–480PubMed Buckwalter JA, Mankin HJ, Grodzinsky AJ (2005) Articular cartilage and osteoarthritis. Instr Course Lect 54:465–480PubMed
15.
go back to reference Luo Y, Sinkeviciute D, He Y, Karsdal M, Henrotin Y, Mobasheri A, Önnerfjord P, Bay-Jensen A (2017) The minor collagens in articular cartilage. Protein Cell 8(8):560–572CrossRef Luo Y, Sinkeviciute D, He Y, Karsdal M, Henrotin Y, Mobasheri A, Önnerfjord P, Bay-Jensen A (2017) The minor collagens in articular cartilage. Protein Cell 8(8):560–572CrossRef
16.
go back to reference Nickla DL, Wallman J (2010) The multifunctional choroid. Prog Retin Eye Res 29(2):144–168CrossRef Nickla DL, Wallman J (2010) The multifunctional choroid. Prog Retin Eye Res 29(2):144–168CrossRef
17.
go back to reference Direskeneli H (2001) Behcet’s disease: infectious aetiology, new autoantigens, and HLA-B51. Ann Rheum Dis 60(11):996–1002CrossRef Direskeneli H (2001) Behcet’s disease: infectious aetiology, new autoantigens, and HLA-B51. Ann Rheum Dis 60(11):996–1002CrossRef
18.
go back to reference Suh CH, Park YB, Song J, Lee CH, Lee SK (2001) Oligoclonal B lymphocyte expansion in the synovium of a patient with Behçet’s disease. Arthritis Rheum 44(7):1707–1712CrossRef Suh CH, Park YB, Song J, Lee CH, Lee SK (2001) Oligoclonal B lymphocyte expansion in the synovium of a patient with Behçet’s disease. Arthritis Rheum 44(7):1707–1712CrossRef
19.
go back to reference Direskeneli H, Keser G, D’Cruz D, Khamashta MA, Akoglu T, Yazici H, Yurdakul S, Hamuryudan V, Ozgun S, Goral AJ et al (1995) Anti-endothelial cell antibodies, endothelial proliferation and von Willebrand factor antigen in Behcet’s disease. Clin Rheumatol 14(1):55–61CrossRef Direskeneli H, Keser G, D’Cruz D, Khamashta MA, Akoglu T, Yazici H, Yurdakul S, Hamuryudan V, Ozgun S, Goral AJ et al (1995) Anti-endothelial cell antibodies, endothelial proliferation and von Willebrand factor antigen in Behcet’s disease. Clin Rheumatol 14(1):55–61CrossRef
24.
Metadata
Title
Ultrasonographic assessment of femoral cartilage thickness in patients with and without uveitis in Behçet’s disease
Authors
Emre Ata
Murat Kosem
Tugba Ozsoy-Unubol
Publication date
01-01-2020
Publisher
Springer Berlin Heidelberg
Keywords
Uveitis
Arthritis
Published in
Rheumatology International / Issue 1/2020
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-019-04361-1

Other articles of this Issue 1/2020

Rheumatology International 1/2020 Go to the issue