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01-07-2015 | Original Article - Observational Research

Relationship between cigarette smoking and radiographic knee osteoarthritis in Chinese population: a cross-sectional study

Authors: Yi Zhang, Chao Zeng, Hui Li, Tuo Yang, Zhen-han Deng, Ye Yang, Xiang Ding, Dong-xing Xie, Yi-lun Wang, Guang-hua Lei

Published in: Rheumatology International | Issue 7/2015

Abstract

The purpose of this paper was to estimate the cross-sectional association between cigarette smoking and radiographic knee Osteoarthritis (OA) in Chinese population. A total of 3,789 subjects (1,796 females and 1,993 males) participated in this study. A subject was diagnosed with radiographic knee OA if Kellgren–Lawrence (K–L) grade ≥2 in at least one leg. The smoking status was classified into four levels based on the daily smoking habit: (1) 0/day; (2) 1–10/day; (3) 11–20/day; and (4) >20/day. Linear trend and multivariable logistic regression were conducted for statistical analysis. The prevalence of radiographic knee OA was 28.4 % among the subjects of this study. An inverse association was observed between cigarette smoking and radiographic knee OA in the linear trend test. Such association remained valid after adjusting the factors of age, gender, body mass index, betel quilt chewing status, physical activity, alcohol drinking status, mean total energy intake and educational level in the multivariable logistic regression. This study suggested a negative association between cigarette smoking and radiographic knee OA in the Chinese population. The findings of this study need to be confirmed by further prospective research.

Felson DT, Lawrence RC, Dieppe PA et al (2000) Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 133:635–646CrossRefPubMed

Spector TD, Cicuttini F, Baker J et al (1996) Genetic influences on osteoarthritis in women: a twin study. BMJ 312:940–943CrossRefPubMedCentralPubMed

Bonnet CS, Walsh DA (2005) Osteoartritis, angiogenesis and inflammation. Rheumatology 44(1):7–16CrossRefPubMed

Felson DT, Zhang Y (1998) An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum 41:1343–1355CrossRefPubMed

Yelin E, Murphy L, Cisternas MG et al (2007) Medical care expenditures and earnings losses among persons with arthritis and other rheumatic conditions in 2003, and comparisons with 1997. Arthritis Rheum 56–5:1397–1407CrossRef

Zhang Y, Jordan JM (2008) Epidemiology of osteoarthritis. Rheum Dis Clin N Am 34(3):515–529CrossRef

Lawrence RC, Felson DT, Helmick CG et al (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum 58(1):26–35CrossRefPubMedCentralPubMed

Giovino GA, Mirza SA, Samet JM et al (2012) Tobacco use in 3 billion individuals from 16 countries: an analysis of nationally representative cross-sectional household surveys. 380. www.thelancet.com

Bartecchi CE, MacKenzie TD, Schrier RW (1994) The human costs of tobacco use (1). N Engl J Med 330:907–912CrossRefPubMed

10.

Sugiyama D, Nishimura K, Tamaki K et al (2010) Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis 69:70–81CrossRefPubMed

11.

Heliövaara M, Aho K, Aromaa A et al (1993) Smoking and risk of rheumatoid arthritis. J Rheumatol 20:1830–1835PubMed

12.

Albano SA, Santana-Sahagun E, Weisman MH (2001) Cigarette smoking and rheumatoid arthritis. Semin Arthritis Rheum 31:146–159CrossRefPubMed

13.

Deyo RA, Bass JE (1989) Lifestyle and low-back pain. The influence of smoking and obesity. Spine 14:501–506CrossRefPubMed

14.

Goldberg MS, Scott SC, Mayo NE (2000) A review of the association between cigarette smoking and the development of nonspecific back pain and related outcomes. Spine 25:995–1014CrossRefPubMed

15.

Fogelholm RR, Alho AV (2001) Smoking and intervertebral disc degeneration. Med Hypotheses 56:537–539CrossRefPubMed

16.

Morens DM, Grandinetti A, Reed D et al (1995) Cigarette smoking and protection from Parkinson’s disease: false association or etiologic clue? Neurology 45:1041–1051CrossRefPubMed

17.

Mahid SS, Minor KS, Soto RE et al (2006) Smoking and inflammatory bowel disease: a meta-analysis. Mayo Clin Proc 81:1462–1471CrossRefPubMed

18.

Cataldo JK, Prochaska JJ, Glantz SA (2010) Cigarette smoking is a risk factor for Alzheimer’s disease: an analysis controlling for tobacco industry affiliation. J Alzheimers Dis 19:465–480PubMedCentralPubMed

19.

Felson DT, Anderson JJ, Naimark A et al (1989) Does smoking protect against osteoarthritis? Arthritis Rheum 32:166–172CrossRefPubMed

20.

Wilder FV, Hall BJ, Barrett JP et al (2003) Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study. Osteoarthr Cartil 11:29–35CrossRefPubMed

21.

Szoeke CEI, Cicuttini FM, Guthrie JR et al (2006) Factors affecting the prevalence of osteoarthritis in healthy middle-aged women: data from the longitudinal Melbourne Women’s Midlife Health Project. Bone 39:1149–1155CrossRefPubMed

22.

Juhakoski R, Heliovaara M, Impivaara O et al (2009) Risk factors for the development of hip osteoarthritis: a population-based prospective study. Rheumatology 48:83–87CrossRefPubMed

23.

Hart DJ, Doyle DV, Spector TD (1999) Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women. Arthritis Rheum 42(1):17–24CrossRefPubMed

24.

Felson DT, Zhang YQ, Hannan MT (1997) Risk factors for incident radographic knee osteoarthritis in the elderly. Arthritis Rheum 40(4):728–733CrossRefPubMed

25.

Hootman JM, Carol ATC, Macera A, Helmick CG (2003) Influence of physical activity-related joint stress on the risk of self-reported hip/knee osteoarthritis: a new method to quantify physical activity. Prev Med 36:636–644CrossRefPubMed

26.

Cheng Y, Macera CA, Davis DR et al (2000) Physical activity and self-reported, physician-diagnosed osteoarthritis: is physical activity a risk factor? J Clin Epidemiol 53:315–322CrossRefPubMed

27.

Amin S, Niu J, Guermazi A et al (2007) Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritis. Ann Rheum Dis 66:18–22CrossRefPubMedCentralPubMed

28.

Hui M, Doherty M, Zhang W (2011) Does smoking protect against osteoarthritis? Meta-analysis of observational studies. Ann Rheum Dis 70:1231–1237CrossRefPubMed

29.

Leung YY, Ang LW, Thumboo J et al (2014) Cigarette smoking and risk of total knee replacement for severe osteoarthritis among Chinese in Singapore—the Singapore Chinese health study. Osteoarthr Cartil 22(6):764–770CrossRefPubMed

30.

Kellgren JH, Lawrence JS (1963) Atlas of standard radiographs: the epidemiology of chronic rheumatism, vol 2. Blackwell, Oxford

31.

Jiang L, Rong J, Zhang Q (2012) Prevalence and associated factors of knee osteoarthritis in a community-based population in Heilongjiang, Northeast China. Rheumatol Int 32(5):1189–1195CrossRefPubMed

32.

Zeng Q, Zang C, Li X (2006) Associated risk factors of knee osteoarthritis: a population survey in Taiyuan, China. Chin Med J 119(18):1522–1527PubMed

33.

Xiang ZY, Mao JC, Qu HR (2013) Epidemiological study on risk factors of knee osteoarthritis in Shanggang Community in Pudong New District. J Shanghai Jiaotong University (Med Sci) 33(3):318–322

34.

Li NH, Zhang YN, Zhang Y (2007) Comparison of the risk factors for knee osteoarthritis in middle-aged and elderly populations from six cities of six administration regions of China. J Clin Rehabil Tissue Eng Res 11(39):7758–7760

35.

Zhang Y, Xu L, Nevitt MC et al (2001) Comparison of the prevalence of knee osteoarthritis between the elderly Chinese population in Beijing and whites in the United States: the Beijing osteoarthritis study. Arthritis Rheum 44:2065–2071CrossRefPubMed

36.

Kang X, Fransen M, Zhang Y et al (2009) The high prevalence of knee osteoarthritis in a rural Chinese population: the Wuchuan osteoarthritis study. Arthritis Rheum 61:641–647CrossRefPubMedCentralPubMed

37.

Zhang N, Shi Q, Zhang X (1995) An epidemiological study of knee osteoarthritis. Zhonghua Nei Ke Za Zhi 34:84–87PubMed

38.

Zeng Q, Huang S, Chen R (1997) 10 year epidemiological study on rheumatic diseases in Shantou area. Zhonghua Nei Ke Za Zhi 36:193–197PubMed

39.

Zhang J, Song L, Liu G et al (2013) Risk factors for and prevalence of knee osteoarthritis in the rural areas of Shanxi Province, North China: a COPCORD study. Rheumatol Int 33(11):2783–2788CrossRefPubMed

40.

Mnatzaganian G, Ryan P, Norman PE et al (2011) Smoking, body weight, physicsl exercise, and risk of lower limb total joint replacement in a population-based cohort of men. Arthritis Rheum 63(8):2523–2530CrossRefPubMed

41.

Mnatzaganian G, Ryan P, Reid CM et al (2013) Smoking and primary total hip or knee replacement due to osteoarthritis in 54,288 elderly men and women. BMC Musculoskelet Disord 5(14):262CrossRef

42.

Jarvholm B, Lewold S, Malchau H (2005) Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men. Eur J Epidemiol 20:537–542CrossRefPubMed

43.

Samanta A, Jones A, Regan M (1993) Is osteoarthritis in women affected by hormonal changes or smoking? Br J Rheumatol 32L:366–370CrossRef

44.

Hart DJ, Spector TD (1993) Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study. Ann Rheum Dis 52:93–96CrossRefPubMedCentralPubMed

45.

Vingard E, Alfredsson L, Malchau H (1997) Lifestyle factors and hip arthrosis A case referent study of body mass index, smoking and hormone therapy in 503 Swedish women. Acta Orfhop Scand 68(3):216–220CrossRef

46.

Kalichman L, Kobyliansky E (2009) Hand osteoarthritis in Chuvashian population: prevalence and determinants. Rheumatol Int 30:85–92CrossRefPubMed

47.

Ying X, Zhang W, Cheng S (2012) Nicotine-induced chondrogenic differentiation of human bone marrow stromal cells in vitro. Knee Surg Sports Traumatol Arthrosc: Off J ESSKA 20(11):2329–2336CrossRef

48.

Ying X, Cheng S, Shen Y (2012) Nicotine promotes proliferation and collagen synthesis of chondrocytes isolated from normal human and osteoarthritis patients. Mol Cell Biochem 359(1–2):263–269CrossRefPubMed

49.

Gullahorn L, Lippiello L, Karpman R (2005) Smoking and osteoarthritis: differential effect of nicotine on human chondrocyte glycosaminoglycan and collagen synthesis. Osteoarthr Cartil 13(10):942–943CrossRefPubMed

50.

Akmal M, Kesani A, Anand B (2004) Effect of nicotine on spinal disc cells: a cellular mechanism for disc degeneration. Spine (Phila Pa 1976) 29:568–575CrossRef

51.

Iwahashi M, Matsuzaki H, Tokuhashi Y (2002) Mechanism of intervertebral disc degeneration caused by nicotine in rabbits to explicate intervertebral disc disorders caused by smoking. Spine (Phila Pa 1976) 27:1396–1401CrossRef

52.

Oda H, Matsuzaki H, Tokuhashi Y (2004) Degeneration of intervertebral discs due to smoking: experimental assessment in a rat-smoking model. J Orthop Sci 9:135–141CrossRefPubMed

53.

Uematsu Y, Matuzaki H, Iwahashi M (2001) Effects of nicotine on the intervertebral disc: an experimental study in rabbits. J Orthop Sci 6:177–182CrossRefPubMed

54.

Pearce F, Hui M, Ding C (2013) Does smoking reduce the progression of osteoarthritis? Meta-analysis of observational studies. Arthritis Care Res 65(7):1026–1033CrossRef

Title: Relationship between cigarette smoking and radiographic knee osteoarthritis in Chinese population: a cross-sectional study
Authors: Yi Zhang
Chao Zeng
Hui Li
Tuo Yang
Zhen-han Deng
Ye Yang
Xiang Ding
Dong-xing Xie
Yi-lun Wang
Guang-hua Lei
Publication date: 01-07-2015
Publisher: Springer Berlin Heidelberg
Published in: Rheumatology International / Issue 7/2015
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-014-3202-0

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