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Rheumatology International
Published in: Rheumatology International 6/2014

01-06-2014 | Letter to the Editor

Evaluation of mean platelet volume in familial Mediterranean fever; insight from the methodological aspect

Author: Ercan Varol

Published in: Rheumatology International | Issue 6/2014

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Excerpt

I read the article published by Ozkayar et al. with great interest [1]. They assessed the mean platelet volume (MPV) levels in familial Mediterranean fever (FMF) patients with and without amyloidosis and compared it with healthy controls. MPV level was significantly higher when compared to the control group in the FMF group. MPV level was significantly lower in secondary amyloidosis (AA) group in comparison with the FMF and healthy control groups. This is an interesting well-designed study. However, I would like to put forward some minor criticism with regard to some methodological and pathophysiological aspects. …
Literature
1.
Ozkayar N, Piskinpasa S, Akyel F, Dede F, Yildirim T, Turgut D, Koc E, Haznedaroglu IC (2013) Evaluation of the mean platelet volume in secondary amyloidosis due to familial Mediterranean fever. Rheumatol Int. May 15 [Epub ahead of print]
2.
Vizioli L, Muscari S, Muscari A (2009) The relationship of mean platelet volume with the risk and prognosis of cardiovascular diseases. Int J Clin Pract 63:1509–1515PubMedCrossRef
3.
Laufer N, Grover NB, Ben-Sasson S, Freund H (1979) Effects of adenosine diphosphate, colchicine and temperature on size of human platelets. Thromb Haemost 41(3):491–497PubMed
4.
Park Y, Schoene N, Haris W (2002) Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets 13:301–306PubMedCrossRef
5.
Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD (2011) Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des 17:47–58PubMedCrossRef
Metadata
Title
Evaluation of mean platelet volume in familial Mediterranean fever; insight from the methodological aspect
Author
Ercan Varol
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
Rheumatology International / Issue 6/2014
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-013-2791-3

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