Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Rheumatology International
Published in: Rheumatology International 5/2013

01-05-2013 | Original Article

Werner’s syndrome may be lost in the shadow of the scleroderma

Authors: Emel Gonullu, Nazife Şule Yaşar Bilge, Timuçin Kaşifoğlu, Cengiz Korkmaz

Published in: Rheumatology International | Issue 5/2013

Login to get access

Abstract

We describe three patients with Werner’s syndrome (WS), two of whom had been mistakenly diagnosed as having scleroderma. We would like to discuss briefly the importance of differentiation of these two disorders from each other.
Literature
1.
Goto M (1997) Hierarchical deterioration of body systems in Werner’s syndrome: implications for normal ageing. Mech Ageing Dev 98(3):239–254PubMedCrossRef
2.
Nakura J, Wijsman EM, Miki T, Kamino K, Yu CE, Oshima J, Fukuchi K, Weber JL, Piussan C, Melaragno MI et al (1994) Homozygosity mapping of the Werner syndrome locus (WRN). Genomics 23(3):600–608PubMedCrossRef
3.
Masala MV, Scapaticci S, Olivieri C, Pirodda C, Montesu MA, Cuccuru MA, Pruneddu S, Danesino C, Cerimele D (2007) Epidemiology and clinical aspects of Werner’s syndrome in North Sardinia: description of a cluster. Eur J Dermatol 17(3):213–216PubMed
4.
Yamamoto K, Imakiire A, Miyagawa N, Kasahara T (2003) A report of two cases of Werner’s syndrome and review of the literature. J Orthop Surg (Hong Kong) 11(2):224–233
5.
Kyng K, Croteau DL, Bohr VA (2009) Werner syndrome resembles normal aging. Cell Cycle 8(15):2323 Epub 2009 Aug 1PubMedCrossRef
6.
Foti R, Leonardi R, Rondinone R, Di Gangi M, Leonetti C, Canova M, Doria A (2008) Scleroderma-like disorders. Autoimmun Rev 7(4):331–339PubMedCrossRef
7.
Ishikawa N, Nakamura K, Izumiyama-Shimomura N, Aida J, Ishii A, Goto M, Ishikawa Y, Asaka R, Matsuura M, Hatamochi A, Kuroiwa M, Takubo K (2011) Accelerated in vivo epidermal telomere loss in Werner syndrome. Aging (Albany NY) 3(4):417–429
8.
Capell BC, Tlougan BE, Orlow SJ (2009) From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging. J Invest Dermatol 129(10):2340–2350 Epub 2009 Apr 23PubMedCrossRef
9.
Goto M, Miller RW, Ishikawa Y, Sugano H (1996) Excess of rare cancers in Werner syndrome (adult progeria). Cancer Epidemiol Biomarkers Prev 5(4):239–246PubMed
10.
Hao S, Feng J, Zhang L, Tang J, Wu Z, Zhang J (2011) Rapid recurrence of petroclival meningioma in Werner syndrome: case report. Clin Neurol Neurosurg 113(9):795–797 Epub 2011 Sep 8PubMedCrossRef
11.
Tsurubuchi T, Yamamoto T, Tsukada Y, Matsuda M, Nakai K, Matsumura A (2008) Meningioma associated with Werner syndrome–case report. Neurol Med Chir (Tokyo) 48(10):470–473CrossRef
12.
Bes C, Vardi S, Güven M, Soy M (2010) Werner’s syndrome: a quite rare disease for differential diagnosis of scleroderma. Rheumatol Int 30(5):695–698 Epub 2009 Jun 3PubMedCrossRef
13.
Sert M, Fakioglu K, Tetiker T (2009) Review of two siblings with Werner’s syndrome: a case report. Case Report Med 2009:138312
Metadata
Title
Werner’s syndrome may be lost in the shadow of the scleroderma
Authors
Emel Gonullu
Nazife Şule Yaşar Bilge
Timuçin Kaşifoğlu
Cengiz Korkmaz
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 5/2013
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-012-2564-4

Other articles of this Issue 5/2013

Rheumatology International 5/2013 Go to the issue

Short Communication

Decreased vitamin D levels in patients with familial mediterranean fever

Original Article

Health-related quality of life in Turkish patients with Ankylosing spondylitis: impact of peripheral involvement on quality of life in terms of disease activity, functional status, severity of pain, and social and emotional functioning

Letter to the Editors

Treatment for mycetoma with oral itraconazole in ankylosing spondylitis

Original Article

Interstitial lung disease in clinically amyopathic dermatomyositis (CADM) patients: a retrospective study of 41 Chinese Han patients

Original Article

Is the prevalence of arterial hypertension in rheumatoid arthritis and osteoarthritis associated with disease?

Original Article

Sexuality of men with fibromyalgia: what are the factors that cause sexual dysfunction?

ACC 2024 Congress Coverage

Heart Failure Video

Year in Review: Heart failure and cardiomyopathies

Watch now

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits