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Published in: Rheumatology International 4/2010

01-02-2010 | Original Article

Back pain and sacroiliitis in long-standing adult celiac disease: a cross-sectional and follow-up study

Authors: Edit Vereckei, Ádám Mester, László Hodinka, Péter Temesvári, Emese Kiss, Gyula Poór

Published in: Rheumatology International | Issue 4/2010

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Abstract

There have been only scattered reports suggesting that musculoskeletal manifestations including back pain and sacroiliac joint involvement may be associated with celiac disease. In order to confirm this issue in a larger cohort, rheumatic manifestations were analyzed in 21 adult celiac patients using a comprehensive clinical, laboratory and radiological analysis. The diagnosis of celiac disease was based on the histopathology of jejunal biopsy specimens. The mean duration of celiac disease was 15 (0–31) years. All patients were currently on gluten-free diet and none of the patients had gastrointestinal symptoms at the time of the study. Using various imaging techniques, involvement of the sacroiliac joints was confirmed in 70% of celiac patients. Imaging revealed different morphological changes in the sacroiliac joint, e.g. accumulation of synovial fluid, synovitis, erosion with concomitant sclerosis, sacroiliitis or calcification of the ligament. These changes probably represent different clinical stages and/or manifestations of the same process. In a follow-up study of eight patients, after 11 years on a gluten-free diet, the great majority of patients had no clinical symptoms; yet, a subclinical progression of the sacroiliac joint involvement could be verified. Our results suggest the importance of regular rheumatologic follow-up of patients with celiac disease.
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Metadata
Title
Back pain and sacroiliitis in long-standing adult celiac disease: a cross-sectional and follow-up study
Authors
Edit Vereckei
Ádám Mester
László Hodinka
Péter Temesvári
Emese Kiss
Gyula Poór
Publication date
01-02-2010
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 4/2010
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-009-0979-3

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