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Published in: Seminars in Immunopathology 2/2007

01-06-2007 | Review

UNK cells: their role in tissue re-modelling and preeclampsia

Authors: Jianhong Zhang, Zhigang Tian

Published in: Seminars in Immunopathology | Issue 2/2007

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Abstract

In different species of mammal, uterine natural killer (uNK) cells are massively recruited and presented at the fetal maternal interface with a spatio-temporal pattern, and regarded as a constructive element to support reproductive development. Recent insights highlight the uNK cells activation, function and interaction with local compartments, which all contribute to the initiation of vascular structural changes. New trends of uNK cells research will benefit the diagnosis, management and test treatment strategy of preeclampsia. Furthermore, we suggest that more efforts and specific studies are needed to further explore the role of uNK cells at the unique micro-environment.
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Metadata
Title
UNK cells: their role in tissue re-modelling and preeclampsia
Authors
Jianhong Zhang
Zhigang Tian
Publication date
01-06-2007
Publisher
Springer-Verlag
Published in
Seminars in Immunopathology / Issue 2/2007
Print ISSN: 1863-2297
Electronic ISSN: 1863-2300
DOI
https://doi.org/10.1007/s00281-007-0068-1

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