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Seminars in Immunopathology
Published in: Seminars in Immunopathology 3/2005

01-01-2005 | Original Paper

Dendritic cell-mediated T cell polarization

Authors: Esther C. de Jong, Hermelijn H. Smits, Martien L. Kapsenberg

Published in: Seminars in Immunopathology | Issue 3/2005

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Abstract

Effective defense against diverse types of micro-organisms that invade our body requires specialized classes of antigen-specific immune responses initiated and maintained by distinct subsets of effector CD4+ T helper (Th) cells. Excessive or detrimental (e.g., autoimmune) responses by effector T cells are controlled by regulatory T cells. The optimal balance in the development of the different types of effector and regulatory Th cells is orchestrated by dendritic cells (DC). This review discusses the way DC adapt the T cell response to the type of pathogen, focusing on the tools that DC use in this management of the T cell response.
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Metadata
Title
Dendritic cell-mediated T cell polarization
Authors
Esther C. de Jong
Hermelijn H. Smits
Martien L. Kapsenberg
Publication date
01-01-2005
Publisher
Springer-Verlag
Published in
Seminars in Immunopathology / Issue 3/2005
Print ISSN: 1863-2297
Electronic ISSN: 1863-2300
DOI
https://doi.org/10.1007/s00281-004-0167-1

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Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

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Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

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