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World Journal of Surgery
Published in: World Journal of Surgery 6/2021

01-06-2021 | Pancreatic Surgery | Original Scientific Report

Changes in Serum Lactate Level Predict Postoperative Intra-Abdominal Infection After Pancreatic Resection

Authors: Yatong Li, Lixin Chen, Cheng Xing, Cheng Ding, Hanyu Zhang, Shunda Wang, Yun Long, Junchao Guo, Quan Liao, Taiping Zhang, Yupei Zhao, Menghua Dai

Published in: World Journal of Surgery | Issue 6/2021

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Abstract

Objective

Postoperative intra-abdominal infection is one of the most serious complications after pancreatic resection. In this article, we investigated the relationship between serum lactate level and postoperative infection, to suggest a new predictor of potential infection risk after pancreatectomy.

Methods

A retrospective analysis of 156 patients who underwent pancreatic surgery and admitted in the intensive care unit for recovery after surgery between August 2017 and August 2019 was performed.

Results

The basic characteristics, preoperative information, pathological diagnoses, surgical methods, and intraoperative situations of patients in the postoperative intra-abdominal infection group (n = 52) and non-infection group (n = 104) showed no significant differences. With the same postoperative treatments and results of fluid balance, blood pressure maintenance, and laboratory tests, postoperative serum lactate level increased much higher in the infection group than non-infection group (P < 0.001), while the base excess level declined much lower (P = 0.002). Patients in the infection group needed more time to elute lactate (P < 0.001), and stayed longer in the intensive care unit after surgery (P = 0.007). The overall postoperative complications were certainly more in the infection group (P < 0.001), resulting in a longer hospitalization time (P < 0.001).

Conclusions

When patients recovered smoothly from anesthesia with a stable hemodynamics situation and normal results of laboratory tests, abnormally high serum lactate level could be a predictor of postoperative intra-abdominal infection after pancreatic resection.
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Metadata
Title
Changes in Serum Lactate Level Predict Postoperative Intra-Abdominal Infection After Pancreatic Resection
Authors
Yatong Li
Lixin Chen
Cheng Xing
Cheng Ding
Hanyu Zhang
Shunda Wang
Yun Long
Junchao Guo
Quan Liao
Taiping Zhang
Yupei Zhao
Menghua Dai
Publication date
01-06-2021
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 6/2021
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-021-05987-8

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