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At a glance: The ONWARDS insulin icodec trials

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Intensive Care Medicine
Published in: Intensive Care Medicine 10/2015

01-10-2015 | Letter

Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials

Authors: Wan-Jie Gu, Zhongheng Zhang, Jan Bakker

Published in: Intensive Care Medicine | Issue 10/2015

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Excerpt

Dear Editor, …
Appendix
Available only for authorised users
Literature
1.
Dellinger RP, Levy MM, Rhodes A et al (2013) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39:165–228CrossRefPubMed
2.
Jansen TC, van Bommel J, Schoonderbeek FJ et al (2010) Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med 182:752–761CrossRefPubMed
3.
Jones AE, Shapiro NI, Trzeciak S et al (2010) Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA 303:739–746PubMedCentralCrossRefPubMed
4.
Tian HH, Han SS, Lv CJ et al (2012) The effect of early goal lactate clearance rate on the outcome of septic shock patients with severe pneumonia. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 24:42–45PubMed
5.
Yu B, Tian HY, Hu ZJ et al (2013) Comparison of the effect of fluid resuscitation as guided either by lactate clearance rate or by central venous oxygen saturation in patients with sepsis. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 25:578–583PubMed
Metadata
Title
Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials
Authors
Wan-Jie Gu
Zhongheng Zhang
Jan Bakker
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 10/2015
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-015-3955-2

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