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Published in: World Journal of Surgery 1/2010

01-01-2010

Risk Factors for Clinical Pancreatic Fistula After Distal Pancreatectomy: Analysis of Consecutive 100 Patients

Authors: Ryuji Yoshioka, Akio Saiura, Rintaro Koga, Makoto Seki, Yoji Kishi, Ryo Morimura, Junji Yamamoto, Toshiharu Yamaguchi

Published in: World Journal of Surgery | Issue 1/2010

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Abstract

Background

The mortality associated with distal pancreatectomy (DP) has declined to <5% in recent years in high-volume centers. However, morbidity remains high, ranging from 32% to 57%. Pancreatic fistula (PF) is the most common complication after DP. The aim of this study was to analyze factors associated with the occurrence of clinical PF.

Methods

A retrospective review was performed of the medical records of 100 patients who underwent DP in our institution between May 2001 and January 2009.

Results

There was no mortality, but morbidity was occurred in 65 patients (65%), with major complications occurring in 9 patients (9%). PF occurred in 50 patients (50%) and clinical PF occurred in 23 patients (23%). Multivariate analysis indicated that independent risk factors for clinical PF were: age younger than 65 years (P = 0.049; odds ratio (OR) 2.958; 95% confidence interval (CI) 1.007–8.688), not ligating the main pancreatic duct (MPD) (P = 0.02; OR 4.933; 95% CI 1.283–18.967), and extended lymphadenectomy (P = 0.008; OR 4.773; 95% CI 1.504–15.145).

Conclusions

Age < 65 years, not ligating the MPD, and extended lymphadenectomy are independent risk factors for clinical PF.
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Metadata
Title
Risk Factors for Clinical Pancreatic Fistula After Distal Pancreatectomy: Analysis of Consecutive 100 Patients
Authors
Ryuji Yoshioka
Akio Saiura
Rintaro Koga
Makoto Seki
Yoji Kishi
Ryo Morimura
Junji Yamamoto
Toshiharu Yamaguchi
Publication date
01-01-2010
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 1/2010
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-009-0300-3

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