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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2008

Open Access 01-12-2008 | Review

Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?

Authors: Matthias Glanemann, Baomin Shi, Feng Liang, Xiao-Gang Sun, Marcus Bahra, Dietmar Jacob, Ulf Neumann, Peter Neuhaus

Published in: World Journal of Surgical Oncology | Issue 1/2008

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Abstract

Tumor related pancreatic surgery has progressed significantly during recent years. Pancreatoduodenectomy (PD) with lymphadenectomy, including vascular resection, still presents the optimal surgical procedure for carcinomas in the head of pancreas. For patients with small or low-grade malignant neoplasms, as well as small pancreatic metastases located in the mid-portion of pancreas, central pancreatectomy (CP) is emerging as a safe and effective option with a low risk of developing de-novo exocrine and/or endocrine insufficiency. Total pancreatectomy (TP) is not as risky as it was years ago and can nowadays safely be performed, but its indication is limited to locally extended tumors that cannot be removed by PD or distal pancreatectomy (DP) with tumor free surgical margins. Consequently, TP has not been adopted as a routine procedure by most surgeons. On the other hand, an aggressive attitude is required in case of advanced distal pancreatic tumors, provided that safe and experienced surgery is available. Due to the development of modern instruments, laparoscopic operations became more and more successful, even in malignant pancreatic diseases. This review summarizes the recent literature on the abovementioned topics.
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Metadata
Title
Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?
Authors
Matthias Glanemann
Baomin Shi
Feng Liang
Xiao-Gang Sun
Marcus Bahra
Dietmar Jacob
Ulf Neumann
Peter Neuhaus
Publication date
01-12-2008
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2008
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-6-123

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