Skip to main content
Top
Published in: World Journal of Surgery 1/2005

01-01-2005 | Original Scientific Reports

Intravenous Contrast-enhanced Computed Tomography in the Diagnosis of Acute Appendicitis

Authors: Naoko Iwahashi, M.D., Ph.D., Yoshimi Kitagawa, M.D., Ph.D., Toshihiko Mayumi, M.D., Ph.D., Hiroshi Kohno, M.D., Ph.D.

Published in: World Journal of Surgery | Issue 1/2005

Login to get access

Abstract

This study evaluated the usefulness of routine, nonfocused intravenous contrast-enhanced computed tomography (CT) in diagnosing acute appendicitis. Also evaluated was the diagnostic value of several findings that were clinically associated with acute appendicitis. Although a number of studies have shown various techniques using CT to be accurate in the diagnosis of acute appendicitis, few studies have focused on CT with using only intravenous contrast material. Computed tomography scan criteria for acute appendicitis have been established chiefly on the basis of appendiceal findings. We, on the other hand, have often observed the following associated conditions during appendectomy: ascites, paresis of the intestine, or thickening of adjacent tissues. In this study, we reviewed the intravenous contrast-enhanced CT scans of 78 patients who had been diagnosed as having acute appendicitis and had subsequently undergone surgery. We also compared the CT scans with patients’ surgical and histological findings. As a way of evaluating clinical ancillary signs, we identified and analyzed individual CT findings that included abnormal appendix, calcified appendicolith, ascites, dilated intestine, and cecal wall thickening. The sensitivity, specificity, and accuracy of intravenous contrast-enhanced CT in surgical cases were found to be 91.9%, 87.5%, and 91.0%, respectively. Individual findings except for abnormal appendix were not significantly common among patients who had acute appendicitis. However, more positive findings were observed in patients who had appendicitis than in those who had normal appendixes. Intravenous contrast-enhanced CT scan is a useful technique in the diagnosis of acute appendicitis. The plurality of ancillary signs in CT scans also appears to be a helpful indicator in the diagnosis of acute appendicitis.
Literature
1.
go back to reference White, H, Stacey, MC, Bell, RF et al. (1992) “The peritoneum, the mesentery, the greater omentum and the acute abdomen. “ In: Young, AE, Burnard, KG (editors), The New Aird’s Companion in Surgical Studies, Churchill Livingstone, Edinburgh, UK, pp 877–953 White, H, Stacey, MC, Bell, RF et al. (1992) “The peritoneum, the mesentery, the greater omentum and the acute abdomen. “ In: Young, AE, Burnard, KG (editors), The New Aird’s Companion in Surgical Studies, Churchill Livingstone, Edinburgh, UK, pp 877–953
2.
go back to reference Addiss, DG, Shaffer, N, Fowler, BS, et al. 1990The epidemiology of appendicitis and appendectomy in the United StatesAm. J. Epidemiol.132910925 Addiss, DG, Shaffer, N, Fowler, BS,  et al. 1990The epidemiology of appendicitis and appendectomy in the United StatesAm. J. Epidemiol.132910925
3.
go back to reference Berry, J,Jr, Malt, RA 1984Appendicitis near its centenaryAnn. Surg.200567575 Berry, J,Jr, Malt, RA 1984Appendicitis near its centenaryAnn. Surg.200567575
4.
go back to reference Lewis, FR, Holcroft, JW, Boey, J, et al. 1975Appendicitis: a critical review of diagnosis and treatment in 1000 casesArch. Surg.110677684 Lewis, FR, Holcroft, JW, Boey, J,  et al. 1975Appendicitis: a critical review of diagnosis and treatment in 1000 casesArch. Surg.110677684
5.
go back to reference Izbicki, JR, Knoefel, WT, Wilker, DK, et al. 1992Accurate diagnosis of acute appendicitis: a retrospective and prospective analysis of 686 patientsEur. J. Surg.158227231 Izbicki, JR, Knoefel, WT, Wilker, DK,  et al. 1992Accurate diagnosis of acute appendicitis: a retrospective and prospective analysis of 686 patientsEur. J. Surg.158227231
6.
go back to reference Ramirez, JM, Deus, J 1994Practical scores to aid decision making in doubtful cases of appendicitisBr. J. Surg.81680683 Ramirez, JM, Deus, J 1994Practical scores to aid decision making in doubtful cases of appendicitisBr. J. Surg.81680683
7.
go back to reference Balthazar, EJ, Birnbaum, BA, Yee, J, et al. 1994Acute appendicitis: CT and US correlation in 100 patientsRadiology1903135 Balthazar, EJ, Birnbaum, BA, Yee, J,  et al. 1994Acute appendicitis: CT and US correlation in 100 patientsRadiology1903135
8.
go back to reference Patrick, M, Rao, PM, James, T 1998Effect of computed tomography of the appendix on treatment of patients and use of hospital resourcesN. Engl. J. Med.338141145 Patrick, M, Rao, PM, James, T 1998Effect of computed tomography of the appendix on treatment of patients and use of hospital resourcesN. Engl. J. Med.338141145
9.
go back to reference Schuler, JG, Shortsleeve, MJ, Goldenson, RS, et al. 1998Is there a role for abdominal computed tomographic scans in appendicitis? ArchSurg.133373377 Schuler, JG, Shortsleeve, MJ, Goldenson, RS,  et al. 1998Is there a role for abdominal computed tomographic scans in appendicitis? ArchSurg.133373377
10.
go back to reference Stroman, DL, Bayouth, CV, Kuhn, JA, et al. 1999The role of computed tomography in the diagnosis of acute appendicitisAm. J. Surg.178485489 Stroman, DL, Bayouth, CV, Kuhn, JA,  et al. 1999The role of computed tomography in the diagnosis of acute appendicitisAm. J. Surg.178485489
11.
go back to reference Wijetunga, R, Tan, BS, Rouse, JC, et al. 2001Diagnostic accuracy of focused appendiceal CT in clinically equivocal cases of acute appendicitisRadiology221747753 Wijetunga, R, Tan, BS, Rouse, JC,  et al. 2001Diagnostic accuracy of focused appendiceal CT in clinically equivocal cases of acute appendicitisRadiology221747753
12.
go back to reference Walker, S, Haun, W, Clark, J, et al. 2001The value of limited computed tomography with rectal contrast in the diagnosis of acute appendicitisAm. J. Surg.180450455 Walker, S, Haun, W, Clark, J,  et al. 2001The value of limited computed tomography with rectal contrast in the diagnosis of acute appendicitisAm. J. Surg.180450455
13.
go back to reference Mullins, ME, Kircher, MF, Ryan, DP, et al. 2001Evaluation of suspected appendicitis in children using limited helical CT and colonic contrast materialAm. J. Roentgenol.1763741 Mullins, ME, Kircher, MF, Ryan, DP,  et al. 2001Evaluation of suspected appendicitis in children using limited helical CT and colonic contrast materialAm. J. Roentgenol.1763741
14.
go back to reference Funaki, B, Grosskreutz, SR, Funaki, CN 1998Using unenhanced helical CT with enteric contrast material for suspected appendicitis in patients treated at a community hospitalAm. J. Roentgenol.1719971001 Funaki, B, Grosskreutz, SR, Funaki, CN 1998Using unenhanced helical CT with enteric contrast material for suspected appendicitis in patients treated at a community hospitalAm. J. Roentgenol.1719971001
15.
go back to reference Jacobs, JE, Birnbaum, BA, Macari, M, et al. 2001Acute appendicitis: comparison of helical CT diagnosis-focused technique with oral contrast material versus nonfocused technique with oral and intravenous contrast materialRadiology220683690 Jacobs, JE, Birnbaum, BA, Macari, M,  et al. 2001Acute appendicitis: comparison of helical CT diagnosis-focused technique with oral contrast material versus nonfocused technique with oral and intravenous contrast materialRadiology220683690
16.
go back to reference Belthazar, EJ, Megibow, AJ, Siegel, SE, et al. 1991Appendicitis: prospective evaluation with high-resolution CTRadiology1802124PubMed Belthazar, EJ, Megibow, AJ, Siegel, SE,  et al. 1991Appendicitis: prospective evaluation with high-resolution CTRadiology1802124PubMed
17.
go back to reference Kamel, IR, Goldberg, SN, Keogan, MT, et al. 2000Right lower quadrant pain and suspected appendicitis: nonfocused appendiceal CT-Review of 100 casesRadiology217159163 Kamel, IR, Goldberg, SN, Keogan, MT,  et al. 2000Right lower quadrant pain and suspected appendicitis: nonfocused appendiceal CT-Review of 100 casesRadiology217159163
18.
go back to reference Tsushima, Y, Yamada, S, Aoki, J, et al. 2002Effect of contrast-enhanced computed tomography on diagnosis and management of acute abdomen in adultsClin. Radiol.57507513 Tsushima, Y, Yamada, S, Aoki, J,  et al. 2002Effect of contrast-enhanced computed tomography on diagnosis and management of acute abdomen in adultsClin. Radiol.57507513
19.
go back to reference Wise, SW, Labuski, MR, Kasales, CJ, et al. 2001Comparative assessment of CT and sonographic techniques for appendiceal imagingAm. J. Roentgenol.176933941 Wise, SW, Labuski, MR, Kasales, CJ,  et al. 2001Comparative assessment of CT and sonographic techniques for appendiceal imagingAm. J. Roentgenol.176933941
20.
go back to reference Choi, D, Park, H, Lee, YR, et al. 2003The most useful findings for diagnosing acute appendicitis on contrast-enhanced helical CTActa Radiol.44574582 Choi, D, Park, H, Lee, YR,  et al. 2003The most useful findings for diagnosing acute appendicitis on contrast-enhanced helical CTActa Radiol.44574582
21.
go back to reference Curtin, KR, Fitzgerald, SW, Nemcek, AA,Jr, et al. 1995CT diagnosis of acute appendicitis: imaging findingsAm. J. Roentgenol.164905909 Curtin, KR, Fitzgerald, SW, Nemcek, AA,Jr,  et al. 1995CT diagnosis of acute appendicitis: imaging findingsAm. J. Roentgenol.164905909
22.
go back to reference Rao, PM, Rhea, JT, Novelline, RA, et al. 1997Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitisAm. J. Roentgenol16912751280 Rao, PM, Rhea, JT, Novelline, RA,  et al. 1997Helical CT combined with contrast material administered only through the colon for imaging of suspected appendicitisAm. J. Roentgenol16912751280
23.
go back to reference Rao, PM, Rhea, JT, Novelline, RA 1997Sensitivity and specificity of the individual CT signs of appendicitis: experience with 200 helical appendiceal CT examinationsJ. Comput. Assist. Tomogr.21686692 Rao, PM, Rhea, JT, Novelline, RA 1997Sensitivity and specificity of the individual CT signs of appendicitis: experience with 200 helical appendiceal CT examinationsJ. Comput. Assist. Tomogr.21686692
24.
go back to reference Belthazar, EJ, Meigibow, AJ, Hulnick, D, et al. 1986CT of appendicitisAm. J. Roentgenol.147705710 Belthazar, EJ, Meigibow, AJ, Hulnick, D,  et al. 1986CT of appendicitisAm. J. Roentgenol.147705710
25.
go back to reference Shin, MS, Ho, KJ 1985Appendicolith. Significance in acute appendicitis and demonstration by computed tomographyDig. Dis. Sci.30184187 Shin, MS, Ho, KJ 1985Appendicolith. Significance in acute appendicitis and demonstration by computed tomographyDig. Dis. Sci.30184187
26.
go back to reference Raman, SS, Lu, DS, Kadell, BM, et al. 2002Accuracy of nonfocused helical CT for the diagnosis of acute appendicitis: a 5-year reviewAm. J. Roentgenol.17813191325 Raman, SS, Lu, DS, Kadell, BM,  et al. 2002Accuracy of nonfocused helical CT for the diagnosis of acute appendicitis: a 5-year reviewAm. J. Roentgenol.17813191325
27.
go back to reference Callahan, MJ, Rodriguez, DP, Taylor, GA 2002CT of appendicitis in childrenRadiology224325332 Callahan, MJ, Rodriguez, DP, Taylor, GA 2002CT of appendicitis in childrenRadiology224325332
28.
go back to reference Choi, YH, Fischer, E, Hoda, SA, et al. 1998Appendiceal CT in 140 cases: diagnostic criteria for acute and necrotizing appendicitisClin. Imaging22252271 Choi, YH, Fischer, E, Hoda, SA,  et al. 1998Appendiceal CT in 140 cases: diagnostic criteria for acute and necrotizing appendicitisClin. Imaging22252271
29.
go back to reference See, TC, Ng, CS, Watson, CJE, et al. 2002Appendicitis: spectrum of appearances on helical CTBr. Radiol.75775781 See, TC, Ng, CS, Watson, CJE,  et al. 2002Appendicitis: spectrum of appearances on helical CTBr. Radiol.75775781
30.
go back to reference Weltman, D, Yu, J, Krumenacker, J,Jr, et al. 2002Diagnosis of acute appendicitis: comparison of 5- and 10-mm CT sections in the same patientRadiology216172177 Weltman, D, Yu, J, Krumenacker, J,Jr,  et al. 2002Diagnosis of acute appendicitis: comparison of 5- and 10-mm CT sections in the same patientRadiology216172177
Metadata
Title
Intravenous Contrast-enhanced Computed Tomography in the Diagnosis of Acute Appendicitis
Authors
Naoko Iwahashi, M.D., Ph.D.
Yoshimi Kitagawa, M.D., Ph.D.
Toshihiko Mayumi, M.D., Ph.D.
Hiroshi Kohno, M.D., Ph.D.
Publication date
01-01-2005
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 1/2005
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-004-7478-1

Other articles of this Issue 1/2005

World Journal of Surgery 1/2005 Go to the issue

Letters to the Editor

Reply

Letters to the Editor

Reply