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Published in: International Orthopaedics 4/2016

01-04-2016 | Original Paper

Meta-analysis shows that obesity may be a significant risk factor for prosthetic joint infections

Authors: Zhongxi Ma, Fengjin Guo, Jun Qi, Wei Xiang, Jinming Zhang

Published in: International Orthopaedics | Issue 4/2016

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Abstract

Purpose

Our aim was to evaluate the association between the different degree of obesity and prosthetic joint infections (PJIs) after total hip replacement (THR) by performing a meta-analysis.

Methods

PubMed, Cochrane library and Embase databases up to May, 2014 were retrieved for identifying relevant studies. Relative risk (RR) and their 95 % confidence intervals (CIs) were used as effect sizes.

Results

A total of 15 articles were included in this meta-analysis. The overall analyses showed that the risk of PJIs in the BMI ≥ 30 group and in BMI ≥ 40 group were significantly higher than that in the BMI < 30 group. As well, the prospective pooled results showed that overweight and obesity could significantly increase the incidence of PJIs.

Conclusions

Our meta-analysis indicates that all of obesity levels can significantly increase the risk of PJIs. However, further studies with more strict design are need in the future.
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Metadata
Title
Meta-analysis shows that obesity may be a significant risk factor for prosthetic joint infections
Authors
Zhongxi Ma
Fengjin Guo
Jun Qi
Wei Xiang
Jinming Zhang
Publication date
01-04-2016
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 4/2016
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-015-2914-4

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