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Published in: Abdominal Radiology 5/2007

01-09-2007

Biliary cystic intraductal papillary mucinous tumor and cystadenoma/cystadenocarcinoma: differentiation by CT

Authors: Jae Hoon Lim, Kee-Taek Jang, Hyunchul Rhim, Young Sun Kim, Kyu Taek Lee, Sung Ho Choi

Published in: Abdominal Radiology | Issue 5/2007

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Abstract

Purpose

To identify differential findings of biliary cystic intraductal papillary mucinous tumor (IPMT) and biliary cystadenoma/cystadenocarcinoma on CT images.

Materials and methods

Records of 7 patients with biliary cystic IPMT and 17 patients with biliary cystadenoma/cystadenocarcinoma were accessed. A pathologist reviewed gross morphologic and microscopic findings and confirmed the diagnosis. Two radiologists who were blind to the pathologic diagnosis reviewed CT images regarding size of cystic mass, mural nodule, septa, calcification, dilatation of the proximal, and distal bile ducts to the tumor, and the results were analyzed using multivariate analysis.

Results

Mural nodule and dilatation of the bile ducts distal to the cystic tumor were more commonly seen in patients with cystic IPMT than in patients with biliary cystadenoma/cystadenocarcinoma and these are statistically significant, the P values being 0.029 and 0.016, respectively. Size of the cystic tumor, presence of septa, calcification, and dilatation of the bile duct proximal to the cystic tumor were not statistically different.

Conclusion

Biliary cystic IPMT could be differentiated from biliary cystadenoma/cystadenocarcinoma on CT images based on the presence of mural nodules and dilatation of the bile ducts distal to the cystic tumor.
Literature
1.
go back to reference Murphy BJ, Casillas J, Ros PR, et al. (1989) The CT appearance of cystic masses of the liver. RadioGraphics 9:307–322PubMed Murphy BJ, Casillas J, Ros PR, et al. (1989) The CT appearance of cystic masses of the liver. RadioGraphics 9:307–322PubMed
2.
go back to reference Buetow PC, Midkiff RB (1997) MR imaging of the liver. Primary malignant neoplasm in the adult. Magn Reson Imaging Clin N Am 5:289–318PubMed Buetow PC, Midkiff RB (1997) MR imaging of the liver. Primary malignant neoplasm in the adult. Magn Reson Imaging Clin N Am 5:289–318PubMed
3.
go back to reference Korobkin M, Stephens DH, Lee JK, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. AJR 153:507–511PubMed Korobkin M, Stephens DH, Lee JK, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. AJR 153:507–511PubMed
4.
go back to reference Buetow PC, Buck JL, Pantongrag-Brown L, et al. (1995) Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. Radiology 196:805–810PubMed Buetow PC, Buck JL, Pantongrag-Brown L, et al. (1995) Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. Radiology 196:805–810PubMed
5.
go back to reference Choi BI, Lim JH, Han MC, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61PubMed Choi BI, Lim JH, Han MC, et al. (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61PubMed
6.
go back to reference Mortele KJ, Ros PR (2001) Cystic focal liver lesions in the adult: differential CT and MR imaging features. RadioGraphics 21:895–910PubMed Mortele KJ, Ros PR (2001) Cystic focal liver lesions in the adult: differential CT and MR imaging features. RadioGraphics 21:895–910PubMed
7.
go back to reference Forrest ME, Cho KJ, Shields JJ, et al. (1980) Biliary cystadenomas: sonographic-angiographic-pathologic correlations. AJR 135:723–727PubMed Forrest ME, Cho KJ, Shields JJ, et al. (1980) Biliary cystadenomas: sonographic-angiographic-pathologic correlations. AJR 135:723–727PubMed
8.
go back to reference Frick MP, Feinberg SB (1982) Biliary cystadenoma. AJR 139:393–395PubMed Frick MP, Feinberg SB (1982) Biliary cystadenoma. AJR 139:393–395PubMed
9.
go back to reference Nakanuma Y, Sasaki M, Ishikawa A, Tsui W, Chen TC, Huang SF (2002) Biliary papillary neoplasm of the liver. Histol Histopathol 27:851–861 Nakanuma Y, Sasaki M, Ishikawa A, Tsui W, Chen TC, Huang SF (2002) Biliary papillary neoplasm of the liver. Histol Histopathol 27:851–861
10.
go back to reference Lim JH, Yoon KH, Kim SH, et al. (2004) Intraductal papillary mucinous tumor of the bile duct. RadioGraphics 24:53–66PubMedCrossRef Lim JH, Yoon KH, Kim SH, et al. (2004) Intraductal papillary mucinous tumor of the bile duct. RadioGraphics 24:53–66PubMedCrossRef
11.
go back to reference Lee JW, Han JK, Kim TK, et al. (2000) CT features of intraductal intrahepatic cholangiocarcinoma. AJR 175:721–725PubMed Lee JW, Han JK, Kim TK, et al. (2000) CT features of intraductal intrahepatic cholangiocarcinoma. AJR 175:721–725PubMed
12.
go back to reference Yoon KH, Han HK, Kim CG, et al. (2000) Malignant papillary neoplasms of the intrahepatic bile ducts: CT and histopathologic features. AJR 175:1135–1139PubMed Yoon KH, Han HK, Kim CG, et al. (2000) Malignant papillary neoplasms of the intrahepatic bile ducts: CT and histopathologic features. AJR 175:1135–1139PubMed
13.
14.
go back to reference Terada T, Taniguchi M (2004) Intraductal oncocytic papillary neoplasm of the liver. Pathol Int 54:116–123PubMedCrossRef Terada T, Taniguchi M (2004) Intraductal oncocytic papillary neoplasm of the liver. Pathol Int 54:116–123PubMedCrossRef
15.
go back to reference Aoki S, Okayama Y, Kitajima Y, et al. (2005) Intrahepatic biliary papilloma morphologically similar to biliary cystadenoma. J Gastroenterol Hepatol 20:321–324PubMedCrossRef Aoki S, Okayama Y, Kitajima Y, et al. (2005) Intrahepatic biliary papilloma morphologically similar to biliary cystadenoma. J Gastroenterol Hepatol 20:321–324PubMedCrossRef
16.
go back to reference Kosumahl M, Pauser U, Peters K, et al. (2004) Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal. Virchow Arch 445:168–178 Kosumahl M, Pauser U, Peters K, et al. (2004) Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal. Virchow Arch 445:168–178
17.
go back to reference Fukushima N, Mukai K (2000) Differential diagnosis between intraductal papillary-mucinous tumors and mucinous cystic tumors of the pancreas. Int J Surg Pathol 8:271–278PubMedCrossRef Fukushima N, Mukai K (2000) Differential diagnosis between intraductal papillary-mucinous tumors and mucinous cystic tumors of the pancreas. Int J Surg Pathol 8:271–278PubMedCrossRef
18.
go back to reference Procacci C, Graziani R, Bicego E, et al. (1996) Intraductal mucin-producing tumors of the pancreas: imaging findings. Radiology 198:249–257PubMed Procacci C, Graziani R, Bicego E, et al. (1996) Intraductal mucin-producing tumors of the pancreas: imaging findings. Radiology 198:249–257PubMed
19.
go back to reference Kim HJ, Kim MH, Lee SK, et al. (2000) Mucin-hypersecreting bile duct tumor characterized by a striking homology with an intraductal papillary mucinous tumor (IPMT) of the pancreas. Endoscopy 32:389–393PubMedCrossRef Kim HJ, Kim MH, Lee SK, et al. (2000) Mucin-hypersecreting bile duct tumor characterized by a striking homology with an intraductal papillary mucinous tumor (IPMT) of the pancreas. Endoscopy 32:389–393PubMedCrossRef
20.
go back to reference Hubens G, Delvaux G, Willems G, et al. (1991) Papillomatosis of the intra- and extrahepatic bile ducts with involvement of the pancreatic duct. Hepatogastroenterology 38:413–418PubMed Hubens G, Delvaux G, Willems G, et al. (1991) Papillomatosis of the intra- and extrahepatic bile ducts with involvement of the pancreatic duct. Hepatogastroenterology 38:413–418PubMed
21.
go back to reference Joo YH, Kim MH, Lee SK, et al. (2000) A case of mucin-hypersecreting intrahepatic bile duct tumor associated with pancreatic intraductal papillary mucinous tumor. Gastrointest Endosc 52:409–412PubMedCrossRef Joo YH, Kim MH, Lee SK, et al. (2000) A case of mucin-hypersecreting intrahepatic bile duct tumor associated with pancreatic intraductal papillary mucinous tumor. Gastrointest Endosc 52:409–412PubMedCrossRef
Metadata
Title
Biliary cystic intraductal papillary mucinous tumor and cystadenoma/cystadenocarcinoma: differentiation by CT
Authors
Jae Hoon Lim
Kee-Taek Jang
Hyunchul Rhim
Young Sun Kim
Kyu Taek Lee
Sung Ho Choi
Publication date
01-09-2007
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 5/2007
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-006-9161-5

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