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Pediatric Radiology
Published in: Pediatric Radiology 4/2023

Open Access 14-11-2022 | Magnetic Resonance Imaging | ESPR

Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits

Authors: Daniel Gräfe, Freerk Prenzel, Franz Wolfgang Hirsch

Published in: Pediatric Radiology | Issue 4/2023

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Abstract

Cystic fibrosis (CF) is one of the most common inherited and life-shortening pulmonary diseases in the Caucasian population. With the widespread introduction of newborn screening and the development of modulator therapy, tremendous advances have been made in recent years both in diagnosis and therapy. Since paediatric CF patients tend to be younger and have lower morbidity, the type of imaging modality that should be used to monitor the disease is often debated. Computed tomography (CT) is sensitive to many pulmonary pathologies, but radiation exposure limits its use, especially in children and adolescents. Conventional pulmonary magnetic resonance imaging (MRI) is a valid alternative to CT and, in most cases, provides sufficient information to guide treatment. Given the expected widespread availability of sequences with ultra-short echo times, there will be even fewer reasons to perform CT for follow-up of patients with CF. This review aims to provide an overview of the process and results of monitoring CF with MRI, particularly for centres not specialising in the disease.
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Metadata
Title
Chest magnetic resonance imaging in cystic fibrosis: technique and clinical benefits
Authors
Daniel Gräfe
Freerk Prenzel
Franz Wolfgang Hirsch
Publication date
14-11-2022
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 4/2023
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-022-05539-9

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