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Pediatric Radiology
Published in: Pediatric Radiology 3/2021

01-03-2021 | Computed Tomography | Original Article

Diagnostic sensitivity and specificity of CT angiography for renal artery stenosis in children

Authors: Gunes Orman, Prakash M. Masand, Kamlesh U. Kukreja, Alisa A. Acosta, R. Paul Guillerman, Siddharth P. Jadhav

Published in: Pediatric Radiology | Issue 3/2021

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Abstract

Background

Children with suspected renal artery stenosis (RAS) are screened with renal Doppler ultrasonography or computed tomography (CT) angiography/magnetic resonance (MR) angiography depending on institutional preference. CT angiography produces images with superior resolution, allowing higher quality multiplanar two-dimensional reformats and three-dimensional reconstructions. However, there is a paucity of data in the literature regarding the utility and diagnostic performance of renal CT angiography in pediatric RAS.

Objective

The objective of this study is to retrospectively review our experience with renal CT angiography in the diagnosis of pediatric RAS relative to digital subtraction angiography (DSA) as the reference standard.

Materials and methods

All patients 0–18 years of age who underwent CT angiography for evaluation of RAS as a cause of hypertension between January 2012 and May 2019 were identified for the study. A total of 131 patients were identified, 23 of whom had DSA correlation.

Results

Twenty-three patients (17 boys, 6 girls) with a mean age of 6 years 3 months (range: 3 months to 14 years 7 months) were included in this study. Of the 59 renal arteries studied by DSA, 22 were abnormal on CT angiography and 20 were abnormal on DSA. Of the 59 renal arteries, CT angiography was true positive in 18 and true negative in 35. The sensitivity and specificity of CT angiography for RAS diagnosis were 90.0% and 89.7%, respectively. CT angiography identified all cases of main RAS.

Conclusion

Renal CT angiography has a high sensitivity and specificity for pediatric RAS diagnosis in patients referred for DSA.
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Metadata
Title
Diagnostic sensitivity and specificity of CT angiography for renal artery stenosis in children
Authors
Gunes Orman
Prakash M. Masand
Kamlesh U. Kukreja
Alisa A. Acosta
R. Paul Guillerman
Siddharth P. Jadhav
Publication date
01-03-2021
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 3/2021
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-020-04852-5

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