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Pediatric Radiology

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01-08-2020 | Vesicorenal Reflux | Original Article

Voiding urosonography and voiding cystourethrography in primary vesicoureteral reflux associated with mild prenatal hydronephrosis: a comparative study

Authors: Ekaterini Siomou, Vasileios Giapros, Anastasios Serbis, George Makrydimas, Frederica Papadopoulou

Published in: Pediatric Radiology | Issue 9/2020

Abstract

Background

Contrast-enhanced harmonic voiding urosonography has been introduced as a sensitive, radiation-free imaging method for the diagnosis of vesicoureteric reflux.

Objective

To evaluate the occurrence/severity of vesicoureteric reflux in infants with mild prenatal hydronephrosis comparing voiding cystourethrography and voiding urosonography.

Materials and methods

Sixty infants with prenatal hydronephrosis were studied (anteriοposterior pelvic diameter 5–9 mm on ultrasound [US] at gestational weeks 21–30). Postnatal US was performed within the first month of life, as well as voiding cystourethrography and contrast-enhanced voiding urosonography at 1.5–2.5 months at the same session.

Results

Vesicoureteric reflux was diagnosed on at least one modality in 19/60 (32%) infants, and more often on contrast-enhanced voiding urosonography (18/60, 30%) than on voiding cystourethrography (8/60, 13%), P=0.046. Among girls, reflux was more often seen on contrast-enhanced voiding urosonography (6/16, 38%) than on voiding cystourethrography (1/16, 6%), P=0.03. Vesicoureteric reflux missed by voiding cystourethrography was more severe (Grades I, II and III in one, nine and four kidney-ureter-units, respectively), compared with a single case missed by contrast-enhanced voiding urosonography (Grade I in one kidney-ureter-unit).

Conclusion

In the absence of a reference standard, our results imply that voiding cystourethrography might underdiagnose reflux, and/or contrast-enhanced voiding urosonography may overdiagnose reflux.

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Title: Voiding urosonography and voiding cystourethrography in primary vesicoureteral reflux associated with mild prenatal hydronephrosis: a comparative study
Authors: Ekaterini Siomou
Vasileios Giapros
Anastasios Serbis
George Makrydimas
Frederica Papadopoulou
Publication date: 01-08-2020
Publisher: Springer Berlin Heidelberg
Keywords: Vesicorenal Reflux
Ultrasound
Urinary Tract Infection
Ultrasound
Published in: Pediatric Radiology / Issue 9/2020
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-020-04724-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Voiding urosonography and voiding cystourethrography in primary vesicoureteral reflux associated with mild prenatal hydronephrosis: a comparative study

Abstract

Background

Objective

Materials and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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