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Published in: Pediatric Radiology 10/2017

Open Access 01-09-2017 | Minisymposium: Imaging of childhood tuberculosis

Intrathoracic tuberculous lymphadenopathy in children: a guide to chest radiography

Authors: Anthony George, Savvas Andronikou, Tanyia Pillay, Pierre Goussard, Heather J. Zar

Published in: Pediatric Radiology | Issue 10/2017

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Abstract

Making the diagnosis of pulmonary tuberculosis in children can be difficult because microbiological confirmation is not often achieved. Diagnosis is therefore often based on clinical features in combination with chest radiograph findings. Chest radiographs can demonstrate lymphadenopathy of the hilar and para-tracheal regions on the anteroposterior view, and subcarinal lymphadenopathy on the lateral view. However poor interobserver agreement has been reported for radiologist and clinician assessment of lymphadenopathy. This might reflect the lack of standardised imaging criteria for diagnosis as well as radiologists’ objectives for achieving sensitivity rather than specificity. In this paper the authors provide a pictorial aid of chest radiographs in children with culture-confirmed tuberculosis to help clinicians identify lymph node enlargement in primary pulmonary tuberculosis. This collection of images comprises chest radiographs accompanied by schematics and either CT or MRI scan confirmation of pathological lymph node enlargement at the positions commonly affected in tuberculosis.
Literature
1.
go back to reference Steingart KR, Ng V, Henry M et al (2006) Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 6:664–674CrossRefPubMed Steingart KR, Ng V, Henry M et al (2006) Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 6:664–674CrossRefPubMed
2.
go back to reference Andronikou S, Wieselthaler N (2004) Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. Pediatr Radiol 34:861–875CrossRefPubMed Andronikou S, Wieselthaler N (2004) Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. Pediatr Radiol 34:861–875CrossRefPubMed
3.
go back to reference Marais BJ, Gie RP, Schaaf HS et al (2004) A proposed radiological classification of childhood intra-thoracic tuberculosis. Pediatr Radiol 34:886–894CrossRefPubMed Marais BJ, Gie RP, Schaaf HS et al (2004) A proposed radiological classification of childhood intra-thoracic tuberculosis. Pediatr Radiol 34:886–894CrossRefPubMed
4.
go back to reference Du Toit G, Swingler G, Iloni K (2002) Observer variation in detecting lymphadenopathy on chest radiography. Int J Tuberc Lung Dis 6:814–817PubMed Du Toit G, Swingler G, Iloni K (2002) Observer variation in detecting lymphadenopathy on chest radiography. Int J Tuberc Lung Dis 6:814–817PubMed
5.
go back to reference Lucas S, Andronikou S, Goussard P et al (2012) CT features of lymphobronchial tuberculosis in children, including complications and associated abnormalities. Pediatr Radiol 42:923–931CrossRefPubMed Lucas S, Andronikou S, Goussard P et al (2012) CT features of lymphobronchial tuberculosis in children, including complications and associated abnormalities. Pediatr Radiol 42:923–931CrossRefPubMed
6.
go back to reference Moseme T, Andronikou S (2014) Through the eye of the suprasternal notch: point-of-care sonography for tuberculous mediastinal lymphadenopathy in children. Pediatr Radiol 44:681–684CrossRefPubMed Moseme T, Andronikou S (2014) Through the eye of the suprasternal notch: point-of-care sonography for tuberculous mediastinal lymphadenopathy in children. Pediatr Radiol 44:681–684CrossRefPubMed
7.
go back to reference Zar HJ, Andronikou S (2015) Chest X-rays for screening of paediatric PTB: child selection and standardised radiological criteria are key. Int J Tuberc Lung Dis 19:1411CrossRefPubMed Zar HJ, Andronikou S (2015) Chest X-rays for screening of paediatric PTB: child selection and standardised radiological criteria are key. Int J Tuberc Lung Dis 19:1411CrossRefPubMed
8.
go back to reference Andronikou S, Vanhoenacker FM, De Backer AI (2009) Advances in imaging chest tuberculosis: blurring of differences between children and adults. Clin Chest Med 30:717–744CrossRefPubMed Andronikou S, Vanhoenacker FM, De Backer AI (2009) Advances in imaging chest tuberculosis: blurring of differences between children and adults. Clin Chest Med 30:717–744CrossRefPubMed
9.
go back to reference Williams GJ, Macaskill P, Kerr M et al (2013) Variability and accuracy in interpretation of consolidation on chest radiography for diagnosing pneumonia in children under 5 years of age. Pediatr Pulmonol 48:1195–1200CrossRefPubMed Williams GJ, Macaskill P, Kerr M et al (2013) Variability and accuracy in interpretation of consolidation on chest radiography for diagnosing pneumonia in children under 5 years of age. Pediatr Pulmonol 48:1195–1200CrossRefPubMed
10.
go back to reference Kim WS, Choi JI, Cheon JE et al (2006) Pulmonary tuberculosis in infants: radiographic and CT findings. AJR Am J Roentgenol 187:1024–1033CrossRefPubMed Kim WS, Choi JI, Cheon JE et al (2006) Pulmonary tuberculosis in infants: radiographic and CT findings. AJR Am J Roentgenol 187:1024–1033CrossRefPubMed
11.
go back to reference Sodhi KS, Khandelwal N, Saxena AK et al (2016) Rapid lung MRI in children with pulmonary infections: time to change our diagnostic algorithms. J Magn Reson Imaging 43:1196–1206CrossRefPubMed Sodhi KS, Khandelwal N, Saxena AK et al (2016) Rapid lung MRI in children with pulmonary infections: time to change our diagnostic algorithms. J Magn Reson Imaging 43:1196–1206CrossRefPubMed
12.
go back to reference Peprah KO, Andronikou S, Goussard P (2012) Characteristic magnetic resonance imaging low T2 signal intensity of necrotic lung parenchyma in children with pulmonary tuberculosis. J Thorac Imaging 27:171–174CrossRefPubMed Peprah KO, Andronikou S, Goussard P (2012) Characteristic magnetic resonance imaging low T2 signal intensity of necrotic lung parenchyma in children with pulmonary tuberculosis. J Thorac Imaging 27:171–174CrossRefPubMed
13.
go back to reference International Labour Office (2011) Guidelines for the use of the ILO international classification of radiographs of pneumoconiosis. Occupational safety and health series no. 22 (rev 2011). International Labour Office, Geneva International Labour Office (2011) Guidelines for the use of the ILO international classification of radiographs of pneumoconiosis. Occupational safety and health series no. 22 (rev 2011). International Labour Office, Geneva
14.
go back to reference Tajima A, Suzuki C, Kikuchi I et al (2001) (2016) Efficacy of the echo pattern classification of ovarian tumors 2000 in conjunction with transvaginal ultrasonography for diagnosis of ovarian masses. J Med Ultrason 43:249–255CrossRef Tajima A, Suzuki C, Kikuchi I et al (2001) (2016) Efficacy of the echo pattern classification of ovarian tumors 2000 in conjunction with transvaginal ultrasonography for diagnosis of ovarian masses. J Med Ultrason 43:249–255CrossRef
Metadata
Title
Intrathoracic tuberculous lymphadenopathy in children: a guide to chest radiography
Authors
Anthony George
Savvas Andronikou
Tanyia Pillay
Pierre Goussard
Heather J. Zar
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 10/2017
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-017-3890-1

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