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01-01-2010 | Minisymposium

Magnetic resonance spectroscopy in pediatric neuroradiology: clinical and research applications

Authors: Ashok Panigrahy, Marvin D. Nelson Jr., Stefan Blüml

Published in: Pediatric Radiology | Issue 1/2010

Abstract

Magnetic resonance spectroscopy (MRS) offers a unique, noninvasive approach to assess pediatric neurological abnormalities at microscopic levels by quantifying cellular metabolites. The most widely available MRS method, proton (¹H; hydrogen) spectroscopy, is FDA approved for general use and can be ordered by clinicians for pediatric neuroimaging studies if indicated. There are a multitude of both acquisition and post-processing methods that can be used in the implementation of MR spectroscopy. MRS in pediatric neuroimaging is challenging to interpret because of dramatic normal developmental changes that occur in metabolites, particularly in the first year of life. Still, MRS has been proven to provide additional clinically relevant information for several pediatric neurological disease processes such as brain tumors, infectious processes, white matter disorders, and neonatal injury. MRS can also be used as a powerful quantitative research tool. In this article, specific research applications using MRS will be demonstrated in relation to neonatal brain injury and pediatric brain tumor imaging.

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Title: Magnetic resonance spectroscopy in pediatric neuroradiology: clinical and research applications
Authors: Ashok Panigrahy
Marvin D. Nelson Jr.
Stefan Blüml
Publication date: 01-01-2010
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 1/2010
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-009-1450-z

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Magnetic resonance spectroscopy in pediatric neuroradiology: clinical and research applications

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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Other articles of this Issue 1/2010

MR imaging of the fetal brain

Diffusion imaging and tractography of congenital brain malformations

PET imaging in pediatric neuroradiology: current and future applications

‘Molar tooth’ sign in Joubert syndrome

Pediatric Radiology Continuing Medical Education activity

Hermes