Skip to main content
Top
Published in: Pediatric Cardiology 6/2016

01-08-2016 | Original Article

Preoperative Intubation and Lack of Enteral Nutrition are Associated with Prolonged Stay After Arterial Switch Operation

Authors: Ilias Iliopoulos, Redmond Burke, Robert Hannan, Juan Bolivar, David S. Cooper, Farhan Zafar, Anthony Rossi

Published in: Pediatric Cardiology | Issue 6/2016

Login to get access

Abstract

Mortality for the arterial switch operation (ASO) has diminished significantly over the past few decades. Some patients do, however, continue to have protracted and complicated courses after surgery. We attempted to determine which preoperative factors were best associated with prolonged hospital stay after ASO. We retrospectively reviewed all patients that underwent an ASO over a 10-year period. Outcomes of patients with postoperative stays (POS) >14 days (long stay group-LS) were compared with those patients with POS < 7 days (short stay group-SS). The following variables were evaluated: age at surgery, weight, septostomy performed (BAS) and management the day prior to surgery including use of prostaglandin E1 (PGE1), inotropes, intubation status and the establishment of enteral feeds. The SS group had 25 patients and the LS group had 32 patients. Both groups (SS vs. LS) were similar in PGE1 use (48 vs. 69 %), BAS (76 vs. 59 %), age at surgery (6 vs. 7 days) and preoperative inotropes (12 vs. 38 %). The SS group had significantly higher incidence of preoperative feeding (80 vs. 31 %, p < 0.001) and less frequent intubation (12 vs. 47 %, p < 0.001). Patients who are intubated and have not yet begun to receive enteral feeds at the time of their ASO are more likely to have prolonged POS. It is unclear if prolonged stays were a result of operating on patients with worse preoperative hemodynamics or a consequence of a preoperative management strategy that did not allow for extubation and establishment of feeds prior to surgery.
Literature
1.
2.
go back to reference Williams WG, McCrindle BW, Ashburn DA (2003) Outcomes of 829 neonates with complete transposition of the great arteries 12–17 years after repair. Eur J Cardiothorac Surg 24(1):1–9CrossRefPubMed Williams WG, McCrindle BW, Ashburn DA (2003) Outcomes of 829 neonates with complete transposition of the great arteries 12–17 years after repair. Eur J Cardiothorac Surg 24(1):1–9CrossRefPubMed
3.
go back to reference Qamar ZA, Goldberg CS, Devaney EJ (2007) Current risk factors and outcomes for the arterial switch operation. Ann Thorac Surg 84(3):871–878CrossRefPubMed Qamar ZA, Goldberg CS, Devaney EJ (2007) Current risk factors and outcomes for the arterial switch operation. Ann Thorac Surg 84(3):871–878CrossRefPubMed
5.
go back to reference Pagowska-Klimek I, Pychynska-Pokorska M, Krajewski W (2011) Predictors of long intensive care unit stay following cardiac surgery in children. Eur J Cardiothorac Surg 40(1):179–184CrossRefPubMed Pagowska-Klimek I, Pychynska-Pokorska M, Krajewski W (2011) Predictors of long intensive care unit stay following cardiac surgery in children. Eur J Cardiothorac Surg 40(1):179–184CrossRefPubMed
6.
go back to reference Gillespie M, Kuijpers M, Van Rossem M (2006) Determinants of intensive care unit length of stay for infants undergoing cardiac surgery. Congenit Heart Dis 1(4):152–160CrossRefPubMed Gillespie M, Kuijpers M, Van Rossem M (2006) Determinants of intensive care unit length of stay for infants undergoing cardiac surgery. Congenit Heart Dis 1(4):152–160CrossRefPubMed
7.
go back to reference Newburger JW, Wypij D, Bellinger DC et al (2003) Length of stay after infant heart surgery is related to cognitive outcome at age 8 years. J Pediatr 143(1):67–73CrossRefPubMed Newburger JW, Wypij D, Bellinger DC et al (2003) Length of stay after infant heart surgery is related to cognitive outcome at age 8 years. J Pediatr 143(1):67–73CrossRefPubMed
8.
go back to reference Bellinger DC, Newburger JW, Wypij D (2009) Behaviour at eight years in children with surgically corrected transposition: the Boston Circulatory Arrest Trial. Cardiol Young 19(1):86–97 (Epub 2008 Dec 11) CrossRefPubMed Bellinger DC, Newburger JW, Wypij D (2009) Behaviour at eight years in children with surgically corrected transposition: the Boston Circulatory Arrest Trial. Cardiol Young 19(1):86–97 (Epub 2008 Dec 11) CrossRefPubMed
9.
go back to reference Daebritz SH, Nollert G, Sachweh JS (2000) Anatomical risk factors for mortality and cardiac morbidity after arterial switch operation. Ann Thorac Surg 69(6):1880–1886CrossRefPubMed Daebritz SH, Nollert G, Sachweh JS (2000) Anatomical risk factors for mortality and cardiac morbidity after arterial switch operation. Ann Thorac Surg 69(6):1880–1886CrossRefPubMed
10.
go back to reference Wernovsky G, Wypij D, Jonas RA (1995) Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation 92(8):2226–2235CrossRefPubMed Wernovsky G, Wypij D, Jonas RA (1995) Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation 92(8):2226–2235CrossRefPubMed
11.
go back to reference Wernovsky G, Mayer JE Jr, Jonas RA (1995) Factors influencing early and late outcome of the arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg 109(2):289–301CrossRefPubMed Wernovsky G, Mayer JE Jr, Jonas RA (1995) Factors influencing early and late outcome of the arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg 109(2):289–301CrossRefPubMed
12.
go back to reference Prandstetter C, Hofer A, Lechner E, Mair R, Sames-Dolzer E, Tulzer G (2007) Early and mid-term outcome of the arterial switch operation in 114 consecutive patients. A single centre experience. Clin Res Cardiol 96(10):723–729 (Epub 2007 Aug 13) CrossRefPubMed Prandstetter C, Hofer A, Lechner E, Mair R, Sames-Dolzer E, Tulzer G (2007) Early and mid-term outcome of the arterial switch operation in 114 consecutive patients. A single centre experience. Clin Res Cardiol 96(10):723–729 (Epub 2007 Aug 13) CrossRefPubMed
13.
go back to reference Lalezari S, Bruggemans EF, Blom NA, Hazekamp MG (2011) Thirty-year experience with the arterial switch operation. Ann Thorac Surg 92(3):973–979CrossRefPubMed Lalezari S, Bruggemans EF, Blom NA, Hazekamp MG (2011) Thirty-year experience with the arterial switch operation. Ann Thorac Surg 92(3):973–979CrossRefPubMed
14.
go back to reference Ungerleider RM, Bengur AR, Kessenich AL et al (1997) Risk factors for higher cost in congenital heart operations. Ann Thorac Surg 64(1):44–48CrossRefPubMed Ungerleider RM, Bengur AR, Kessenich AL et al (1997) Risk factors for higher cost in congenital heart operations. Ann Thorac Surg 64(1):44–48CrossRefPubMed
15.
go back to reference Wheeler DS, Dent CL, Manning PB (2008) Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young 18(1):41–50CrossRefPubMed Wheeler DS, Dent CL, Manning PB (2008) Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young 18(1):41–50CrossRefPubMed
16.
go back to reference Kelleher DK, Laussen P, Teixeira-Pinto A (2006) Growth and correlates of nutritional status among infants with hypoplastic left heart syndrome (HLHS) after stage 1 Norwood procedure. Nutrition 22(3):237–244CrossRefPubMed Kelleher DK, Laussen P, Teixeira-Pinto A (2006) Growth and correlates of nutritional status among infants with hypoplastic left heart syndrome (HLHS) after stage 1 Norwood procedure. Nutrition 22(3):237–244CrossRefPubMed
17.
go back to reference Schwalbe-Terilli CR, Hartman DH, Nagle ML et al (2009) Enteral feeding and caloric intake in neonates after cardiac surgery. Am J Crit Care 18(1):52–57CrossRefPubMed Schwalbe-Terilli CR, Hartman DH, Nagle ML et al (2009) Enteral feeding and caloric intake in neonates after cardiac surgery. Am J Crit Care 18(1):52–57CrossRefPubMed
18.
go back to reference Owens JL, Musa N (2009) Nutrition support after neonatal cardiac surgery. Nutr Clin Pract 24(2):242–249CrossRefPubMed Owens JL, Musa N (2009) Nutrition support after neonatal cardiac surgery. Nutr Clin Pract 24(2):242–249CrossRefPubMed
19.
go back to reference Pierro A (2002) Metabolism and nutritional support in the surgical neonate. J Pediatr Surg 37(6):811–822 (Review) CrossRefPubMed Pierro A (2002) Metabolism and nutritional support in the surgical neonate. J Pediatr Surg 37(6):811–822 (Review) CrossRefPubMed
20.
go back to reference Medoff-Cooper B, Naim M, Torowicz D, Mott A (2010) Feeding, growth, and nutrition in children with congenitally malformed hearts. Cardiol Young 20(Suppl 3):149–153CrossRefPubMed Medoff-Cooper B, Naim M, Torowicz D, Mott A (2010) Feeding, growth, and nutrition in children with congenitally malformed hearts. Cardiol Young 20(Suppl 3):149–153CrossRefPubMed
21.
go back to reference Sables-Baus S, Kaufman J, Cook P (2012) Oral feeding outcomes in neonates with congenital cardiac disease undergoing cardiac surgery. Cardiol Young 22(1):42–48CrossRefPubMed Sables-Baus S, Kaufman J, Cook P (2012) Oral feeding outcomes in neonates with congenital cardiac disease undergoing cardiac surgery. Cardiol Young 22(1):42–48CrossRefPubMed
22.
go back to reference Brown KL, Ridout DA, Goldman AP, Hoskote A, Penny DJ (2003) Risk factors for long intensive care unit stay after cardiopulmonary bypass in children. Crit Care Med 31(1):28–33CrossRefPubMed Brown KL, Ridout DA, Goldman AP, Hoskote A, Penny DJ (2003) Risk factors for long intensive care unit stay after cardiopulmonary bypass in children. Crit Care Med 31(1):28–33CrossRefPubMed
23.
go back to reference Butts RJ, Ellis AR, Bradley SM, Hulsey TC, Atz AM (2012) Effect of prostaglandin duration on outcomes in transposition of the great arteries with intact ventricular septum. Congenit Heart Dis 7(4):387–391CrossRefPubMedPubMedCentral Butts RJ, Ellis AR, Bradley SM, Hulsey TC, Atz AM (2012) Effect of prostaglandin duration on outcomes in transposition of the great arteries with intact ventricular septum. Congenit Heart Dis 7(4):387–391CrossRefPubMedPubMedCentral
24.
go back to reference Beattie LM, McLeod KA (2009) Prostaglandin E2 after septostomy for simple transposition. Pediatr Cardiol 30(4):447–451CrossRefPubMed Beattie LM, McLeod KA (2009) Prostaglandin E2 after septostomy for simple transposition. Pediatr Cardiol 30(4):447–451CrossRefPubMed
25.
go back to reference Walch L, Labat C, Gascard JP, de Montpreville V, Brink C, Norel X (1999) Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br J Pharmacol 126(4):859–866CrossRefPubMedPubMedCentral Walch L, Labat C, Gascard JP, de Montpreville V, Brink C, Norel X (1999) Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br J Pharmacol 126(4):859–866CrossRefPubMedPubMedCentral
26.
go back to reference Avila-Alvarez A, Bravo-Laguna MC, Bronte LD, Del Cerro MJ (2013) Inhaled iloprost as a rescue therapy for transposition of the great arteries with persistent pulmonary hypertension of the newborn. Pediatr Cardiol 34(8):2027–2029CrossRefPubMed Avila-Alvarez A, Bravo-Laguna MC, Bronte LD, Del Cerro MJ (2013) Inhaled iloprost as a rescue therapy for transposition of the great arteries with persistent pulmonary hypertension of the newborn. Pediatr Cardiol 34(8):2027–2029CrossRefPubMed
27.
go back to reference Baylen BG, Grzeszczak M, Gleason ME (1992) Role of balloon atrial septostomy before early arterial switch repair of transposition of the great arteries. J Am Coll Cardiol 19(5):1025–1031CrossRefPubMed Baylen BG, Grzeszczak M, Gleason ME (1992) Role of balloon atrial septostomy before early arterial switch repair of transposition of the great arteries. J Am Coll Cardiol 19(5):1025–1031CrossRefPubMed
28.
go back to reference Pagowska-Klimek I, Pychynska-Pokorska M, Krajewski W, Moll JJ (2011) Predictors of long intensive care unit stay following cardiac surgery in children. Eur J Cardiothorac Surg 40(1):179–184CrossRefPubMed Pagowska-Klimek I, Pychynska-Pokorska M, Krajewski W, Moll JJ (2011) Predictors of long intensive care unit stay following cardiac surgery in children. Eur J Cardiothorac Surg 40(1):179–184CrossRefPubMed
Metadata
Title
Preoperative Intubation and Lack of Enteral Nutrition are Associated with Prolonged Stay After Arterial Switch Operation
Authors
Ilias Iliopoulos
Redmond Burke
Robert Hannan
Juan Bolivar
David S. Cooper
Farhan Zafar
Anthony Rossi
Publication date
01-08-2016
Publisher
Springer US
Published in
Pediatric Cardiology / Issue 6/2016
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-016-1394-7

Other articles of this Issue 6/2016

Pediatric Cardiology 6/2016 Go to the issue