Published in:
01-02-2006
Nesiritide Use for Critically Ill Children Awaiting Cardiac Transplantation
Published in: Pediatric Cardiology | Issue 1/2006
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Background
This study aimed to explore the effects of nesiritide in children awaiting cardiac transplantation.
Methods
At the discretion of the attending physician, nesiritide was added to standard therapy for seven children (median age, 11 months) and continued until clinical improvement or transplantation. Blood pressure and urine output data were compared with data from the day before nesiritide institution. Safety parameters were assessed throughout the study.
Results
Urine output increased from 2.6 to 3.6 ml/kg/h (p = 0.04). No significant blood pressure changes or adverse effects related to nesiritide were noted.
Conclusion
Nesiritide may be safe and effective for children with severe heart failure.