Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Neuroradiology
Published in: Neuroradiology 5/2004

01-05-2004 | Paediatric Neuroradiology

Granulocytic sarcoma in children

Authors: L. Porto, M. Kieslich, D. Schwabe, F. E. Zanella, H. Lanfermann

Published in: Neuroradiology | Issue 5/2004

Login to get access

Abstract

We report three children with leukaemia (two acute myeloid and one acute lymphoblastic) and granulocytic sarcoma in the skull, orbit and sinuses. Lesions in these sites in children, with or without bone changes, are suggestive of systemic diseases such as lymphoproliferative conditions. Although involvement by granulocytic sarcoma, with or without acute myeloid leukaemia, is described, an association with acute lymphoblastic leukaemia is rare. Recognition of this rare entity is important, because early aggressive chemotherapy can bring about regression of the tumour and improve survival.
Literature
1.
Pui CH (1999) Childhood leukaemias. Cambridge University Press, Cambridge, pp 288–312, 443–481
2.
Binder C, Tiemann M, Haase D, Humpe A, Kneba M (2000) Isolated meningeal chloroma (granulocytic sarcoma)—a case report and a review of the literature. Ann Hematol 79: 459–462CrossRefPubMed
3.
Libson E, Bloom RA, Galun E, Polliack A (1986) Granulocytic sarcoma (chloroma) of bone: the CT appearance. Comput Radiol 10: 175–178
4.
McCarty KS Jr, Wortmen J, Daly J, Rundles RW, Hanker JS (1980) Chloroma without evidence of leukemia: facilitated light microscopic diagnosis. Blood 56: 104–108PubMed
5.
Esmaeli B, Medeiros LJ, Myers J, Champlin R, Singh S, Ginsberg L (2001) Orbital mass secondary to precursor T-cell acute lymphoblastic leukemia: a rare presentation. Arch Ophthalmol 119: 443–446PubMed
6.
Vinters HV, Gilbert JJ (1982) Multifocal chloromas of the brain. Surg Neurol 17: 47–51PubMed
7.
Goldberg RA, Rootman J, Cline RA (1990) Tumors metastatic to the orbit: a changing picture. Surv Ophthalmol 35: 1–24PubMed
8.
Albert DM, Rubenstein RA, Scheie HG (1967) Tumor metastasis to the eye. II: Clinical study in infants and children. Am J Ophthalmol 63: 727–732PubMed
Metadata
Title
Granulocytic sarcoma in children
Authors
L. Porto
M. Kieslich
D. Schwabe
F. E. Zanella
H. Lanfermann
Publication date
01-05-2004
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 5/2004
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-003-1127-5

Other articles of this Issue 5/2004

Neuroradiology 5/2004 Go to the issue

Interventional Neuroradiology

Thalamic hemorrhage following carotid angioplasty and stenting

Paediatric Neuroradiology

Major brain lesions detected on sonographic screening of apparently normal term neonates

Diagnostic Neuroradiology

Diffusion-weighted MRI in Lhermitte-Duclos disease: report of two cases

Diagnostic Neuroradiology

MR imaging and spectroscopy in Lhermitte-Duclos disease

Book Review

Recent literature

Interventional Neuroradiology

Emergency stenting to control massive bleeding of injured iliac artery following lumbar disk surgery