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Neuroradiology
Published in: Neuroradiology 5/2004

01-05-2004 | Diagnostic Neuroradiology

Diffusion-weighted MRI in Lhermitte-Duclos disease: report of two cases

Authors: Gul Moonis, Mahanad Ibrahim, Elias R. Melhem

Published in: Neuroradiology | Issue 5/2004

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Abstract

Lhermitte-Duclos disease is a rare benign lesion of uncertain pathogenesis characterized by distortion of the normal cerebellar laminar cytoarchitecture. There is a characteristic MR imaging appearance of a nonenhancing mass in the cerebellar hemisphere with a striated pattern. We report two cases of Lhermitte-Duclos disease and describe findings on diffusion-weighted MR imaging.
Literature
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Kulkantrakorn K, Awwad EE, Levy B, Selhorst JB, Cole HO, Leake D, Gussler JR, Epstein AD, Malik MM (1997) MRI in Lhermitte-Duclos disease. Neurology 48:725–731PubMed
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Nowak DA, Trost HA (2002) Lhermitte-Duclos disease (dysplastic cerebellar gangliocytoma): a malformation, hamartoma, or neoplasm? Acta Neurol Scand 105:137–145CrossRefPubMed
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Padberg GW, Schot DL, VIelvoue GJ, Bots GTAM, de Beer FC (1991) Lhermitte-Duclos disease and Cowden disease: a single phakomatosis. Ann Neurol 29:517–523PubMed
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Williams DW, Elster AD, Ginsberg LE, Stanton C (1992) Recurrent Lhermitte-Duclos disease: report of two cases and association with Cowden’s disease. AJNR 13:287–290
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Robinson S, Cohen A (2000) Cowden diseases and Lhermitte-Duclos disease: characterization of a new phakomatosis. Neurosurgery 46:371–383PubMed
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Klisch J, Jeungling F, Spreer J, Koch D, Thiel T, Buchert M, Arnold S, Feuerhake F, Schumaker M (2001) Lhermitte-Duclos disease: assessment with MR imaging, positron emission tomography, single-photon emission CT, and MR spectroscopy. Am J Neuroradiol 22:824–830PubMed
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Nowak DA, Trost HA, Porr A, Stolzle A, Lumenta CB (2001) Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum). Clin Neurol Neurosurg 103:105–110CrossRefPubMed
Metadata
Title
Diffusion-weighted MRI in Lhermitte-Duclos disease: report of two cases
Authors
Gul Moonis
Mahanad Ibrahim
Elias R. Melhem
Publication date
01-05-2004
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 5/2004
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-004-1190-6

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