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Published in: International Urogynecology Journal 9/2011

01-09-2011 | Review Article

Development of cellular therapy for the treatment of stress urinary incontinence

Authors: Hung-Jen Wang, Yao-Chi Chuang, Michael B. Chancellor

Published in: International Urogynecology Journal | Issue 9/2011

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Abstract

Stress urinary incontinence (SUI) is highly prevalent and associated with a reduced quality of life. An intact rhabdosphincter at the mid-urethra is mandatory to maintain urinary continence. Adult stem cell injection therapy for the regenerative repair of an impaired sphincter is currently at the forefront of incontinence research. The implanted cells will fuse with muscle and release trophic factors promoting nerve and muscle integration. Hereby, we review the use of mesenchymal stem cell therapy for SUI and the experience with the development of muscle-derived stem cells.
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Metadata
Title
Development of cellular therapy for the treatment of stress urinary incontinence
Authors
Hung-Jen Wang
Yao-Chi Chuang
Michael B. Chancellor
Publication date
01-09-2011
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 9/2011
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-011-1432-1

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