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01-08-2006 | Original Article

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

Authors: Aurélie Durufle, Sabine Petrilli, Benoit Nicolas, Sandrine Robineau, François Guillé, Gilles Edan, Philippe Gallien

Published in: International Urogynecology Journal | Issue 4/2006

Abstract

Objective

Our objective was to study the impact of pregnancy and delivery on vesicourethral disorders in patients with multiple sclerosis (MS).

Design and setting

We performed a retrospective chart review of records of women diagnosed with MS who were referred to the clinic.

Participants

A total of 102 women with MS (mean age of 44.7±11.4 years at the time of the study and mean age of 30.0±9.6 years at the onset of MS) participated in the study. The mean duration of disease was 15±10 years. The mean Expanded Disability Status Scale score was 5.4±1.8.

Main outcome measures

For each patient, demographic data, disease characteristics, urological and obstetrical history and urodynamic data were collected. Urinary disorders were classified as irritative (urinary urgency and frequency) or as obstructive (hesitancy of micturition, reduced or interrupted urinary stream and sensation of incomplete bladder emptying). Urodynamic study consisted of cystometry with continuous recording of urethral sphincter electromyography in 77 (76%) cases. Intravesical and intraurethral pressures were recorded. Bladder dysfunctions were classified into neurogenic detrusor overactivity or detrusor underactivity.

Results

Pregnancies and deliveries did not influence symptoms. Moreover, the only statistical difference from a urodynamic point of view was a decrease in maximal urethral closure pressure.

Conclusion

No interaction between pregnancy, delivery and urinary symptoms was found in this study. The effects of pregnancy and delivery seemed to be the same in women with MS and in healthy women, with a tendency towards a decrease in urethral pressure in women with MS.

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Title: Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis
Authors: Aurélie Durufle
Sabine Petrilli
Benoit Nicolas
Sandrine Robineau
François Guillé
Gilles Edan
Philippe Gallien
Publication date: 01-08-2006
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 4/2006
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-005-0012-7

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

Abstract

Objective

Design and setting

Participants

Main outcome measures

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objective

Design and setting

Participants

Main outcome measures

Results

Conclusion

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