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01-06-2019 | Candidiasis | Seven-Day Profile Publication

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients

Authors: Ignacio Martin-Loeches, Massimo Antonelli, Manuel Cuenca-Estrella, George Dimopoulos, Sharon Einav, Jan J. De Waele, Jose Garnacho-Montero, Souha S. Kanj, Flavia R. Machado, Philippe Montravers, Yasser Sakr, Maurizio Sanguinetti, Jean-Francois Timsit, Matteo Bassetti

Published in: Intensive Care Medicine | Issue 6/2019

Abstract

Introduction

The term invasive candidiasis (IC) refers to both bloodstream and deep-seated invasive infections, such as peritonitis, caused by Candida species. Several guidelines on the management of candidemia and invasive infection due to Candida species have recently been published, but none of them focuses specifically on critically ill patients admitted to intensive care units (ICUs).

Material and Methods

In the absence of available scientific evidence, the resulting recommendations are based solely on epidemiological and clinical evidence in conjunction with expert opinion. The task force used the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach to evaluate the recommendations and assign levels of evidence. The recommendations and their strength were decided by consensus and, if necessary, by vote (modified Delphi process). Descriptive statistics were used to analyze the results of the Delphi process. Statements obtaining > 80% agreement were considered to have achieved consensus.

Conclusions

The heterogeneity of this patient population necessitated the creation of a mixed working group comprising experts in clinical microbiology, infectious diseases and intensive care medicine, all chosen on the basis of their expertise in the management of IC and/or research methodology. The working group’s main goal was to provide clinicians with clear and practical recommendations to optimize microbiological diagnosis and treatment of IC. The Systemic Inflammation and Sepsis and Infection sections of the European Society of Intensive Care Medicine (ESICM) and the Critically Ill Patients Study Group of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) therefore decided to develop a set of recommendations for application in non-immunocompromised critically ill patients.

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Title: ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients
Authors: Ignacio Martin-Loeches
Massimo Antonelli
Manuel Cuenca-Estrella
George Dimopoulos
Sharon Einav
Jan J. De Waele
Jose Garnacho-Montero
Souha S. Kanj
Flavia R. Machado
Philippe Montravers
Yasser Sakr
Maurizio Sanguinetti
Jean-Francois Timsit
Matteo Bassetti
Publication date: 01-06-2019
Publisher: Springer Berlin Heidelberg
Keywords: Candidiasis
Candidiasis
Fluconazole
Septicemia
Septicemia
Published in: Intensive Care Medicine / Issue 6/2019
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-019-05599-w

ACC 2024 Congress

Springer Medicine

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients

Abstract

Introduction

Material and Methods

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Introduction

Material and Methods

Conclusions

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