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Published in: Intensive Care Medicine 6/2017

01-06-2017 | Review

Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury

Authors: Sean M. Bagshaw, Michael Darmon, Marlies Ostermann, Fredric O. Finkelstein, Ron Wald, Ashita J. Tolwani, Stuart L. Goldstein, David J. Gattas, Shigehiko Uchino, Eric A. Hoste, Stephane Gaudry

Published in: Intensive Care Medicine | Issue 6/2017

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Abstract

Acute kidney injury (AKI) is associated with incremental risk for death and chronic kidney disease and represents a mounting clinical challenge for healthcare professionals. Renal replacement therapy (RRT) use in ICU settings is rising, likely in response to similar trends in AKI, taken together with an ageing population burdened by high prevalence of multi-morbidity and high illness acuity. Numerous features of RRT prescription and delivery are not standardized, nor are they supported from high-quality evidence derived from randomized trials. Despite the publication of rigorous clinical practice guidelines focused on RRT for AKI that are intended to optimize the quality and reliability of RRT in ICU settings, practice patterns and outcomes continue to show significant variability. In this concise review, we aim to summarize new knowledge and recent advances for the provision of RRT for critically ill patients with AKI.
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Metadata
Title
Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury
Authors
Sean M. Bagshaw
Michael Darmon
Marlies Ostermann
Fredric O. Finkelstein
Ron Wald
Ashita J. Tolwani
Stuart L. Goldstein
David J. Gattas
Shigehiko Uchino
Eric A. Hoste
Stephane Gaudry
Publication date
01-06-2017
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 6/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-017-4762-8

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