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Intensive Care Medicine

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01-12-2004 | Original

Preferred plasma volume expanders for critically ill patients: results of an international survey

Authors: Frédérique Schortgen, Nicolas Deye, Laurent Brochard, for the CRYCO Study Group

Published in: Intensive Care Medicine | Issue 12/2004

Abstract

Objective

Criteria for plasma volume expander selection in critically ill patients remain controversial. This study evaluated preferences of intensivists regarding plasma volume expanders.

Design

International survey using a 75-item questionnaire.

Participants and setting

All members of the European and French Societies of Intensive Care Medicine (n=2,415 in 1,610 adult ICUs in Europe and elsewhere) were invited to participate, and 577 (24%) working in 515 ICUs (32%) returned completed questionnaires.

Results

Among respondents, 17% used crystalloids alone as their first-choice strategy, 18% colloids alone, and 65% both. Colloids alone were often chosen in patients with cirrhosis (42%), coagulation disorders (42%), or adult respiratory distress syndrome (39%); and crystalloids in patients with dehydration (85%), drug overdose (59%), or acute renal failure (49%). First-line plasma expanders were as follows: isotonic crystalloids (81%), starches (55%), gelatins (35%), albumin (7%), plasma (6%), dextrans (4%), and hypertonic crystalloids (2%). Colloids alone were used more frequently in the United Kingdom (40%), starches in Germany (81%) and The Netherlands (66%), and gelatins in the United Kingdom (68%). The main factors behind preferences for first-line plasma volume expanders were time to volume loss correction, duration of effect, adverse events, and cost.

Conclusions

Colloids are widely used as first-line treatment, usually in combination with crystalloids. Starches are the most widely used colloids in Europe, where albumin use is declining. However, strategies vary widely across clinical situations and countries.

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Title: Preferred plasma volume expanders for critically ill patients: results of an international survey
Authors: Frédérique Schortgen
Nicolas Deye
Laurent Brochard
for the CRYCO Study Group
Publication date: 01-12-2004
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 12/2004
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-004-2415-1

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Preferred plasma volume expanders for critically ill patients: results of an international survey

Abstract

Objective

Design

Participants and setting

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objective

Design

Participants and setting

Results

Conclusions

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