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At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Diabetologia
Published in: Diabetologia 7/2014

01-07-2014 | In memoriam

Michaela Diamant, 11 April 1962–9 April 2014

Authors: Robert J. Heine, Hannele Yki-Järvinen, Steven E. Kahn, Daniel H. van Raalte

Published in: Diabetologia | Issue 7/2014

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Excerpt

…
Literature
1.
Rijzewijk LJ, van der Meer RW, Lamb HJ, de Jong HW, Lubberink M, Romijn JA, Bax JJ, de Roos A, Twisk JW, Heine RJ, Lammertsma AA, Smit JW, Diamant M (2009) Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging. J Am Coll Cardiol 54:1524–1532PubMedCrossRef
2.
Woerdeman J, van Duinkerken E, Wattjes MP, Barkhof F, Snoek FJ, Moll AC, Klein M, de Boer MP, Ijzerman RG, Serné EH, Diamant M (2014) Proliferative retinopathy in type 1 diabetes is associated with cerebral microbleeds, which is part of generalized microangiopathy. Diabetes Care 37:1165–1168PubMedCrossRef
3.
Diamant M, Van Gaal L, Stranks S, Northrup J, Cao D, Taylor K, Trautmann M (2010) Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial. Lancet 375:2234–2243PubMedCrossRef
4.
van Raalte DH, Brands M, van der Zijl NJ, Muskiet MH, Pouwels PJ, Ackermans MT, Sauerwein HP, Serlie MJ, Diamant M (2011) Low-dose glucocorticoid treatment affects multiple aspects of intermediary metabolism in healthy humans: a randomised controlled trial. Diabetologia 54:2103–2112PubMedCentralPubMedCrossRef
5.
van Raalte DH, Diamant M, Ouwens DM, Ijzerman RG, Linssen MM, Guigas B, Eringa EC, Serné EH (2013) Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial. Diabetologia 56:2383–2391PubMedCrossRef
6.
Steinbusch LK, Schwenk RW, Ouwens DM, Diamant M, Glatz JF, Luiken JJ (2011) Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes. Cell Mol Life Sci 68:2525–2538PubMedCentralPubMedCrossRef
7.
Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH, Diamant M, Guigas B, Ouwens DM (2011) Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells. Cell Signal 23:1708–1715PubMedCrossRef
8.
Bunck MC, Cornér A, Eliasson B, Heine RJ, Shaginian RM, Wu Y, Yan P, Smith U, Yki-Järvinen H, Diamant M, Taskinen MR (2010) One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress. Atherosclerosis 212:223–229PubMedCrossRef
9.
Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR (2012) Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 55:1577–1596PubMedCrossRef
10.
Brands M, van Raalte DH, João Ferraz M, Sauerwein HP, Verhoeven AJ, Aerts JM, Diamant M, Serlie MJ (2013) No difference in glycosphingolipid metabolism and mitochondrial function in glucocorticoid-induced insulin resistance in healthy men. J Clin Endocrinol Metab 98:1219–1225PubMedCrossRef
11.
van Raalte DH, Diamant M (2014) Steroid diabetes: from mechanism to treatment? Neth J Med 72:62–72PubMed
12.
Muskiet MH, Smits MM, Morsink LM, Diamant M (2014) The gut–renal axis: do incretin-based agents confer renoprotection in diabetes? Nat Rev Nephrol 10:88–103PubMedCrossRef
Metadata
Title
Michaela Diamant, 11 April 1962–9 April 2014
Authors
Robert J. Heine
Hannele Yki-Järvinen
Steven E. Kahn
Daniel H. van Raalte
Publication date
01-07-2014
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 7/2014
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-014-3254-4

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