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01-09-2021 | Radiotherapy | Case Study

Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission

Authors: Petra Kovářová, MD, Radovan Vojtíšek, MD, PhD, Michal Krčma, MD, PhD, Prof. Ondřej Daum, MD, PhD, Prof. Jan Baxa, MD, PhD, Emília Sukovská, MD, Prof. Jindřich Fínek, MD, PhD, MHA

Published in: Strahlentherapie und Onkologie | Issue 9/2021

Abstract

Carcinoma showing thymus-like elements (CASTLE) is an extremely rare malignant tumor of the thyroid gland and soft tissues of the neck with favorable prognosis. Histological features of the CASTLE are similar to thymic carcinoma, and it is assumed that it arises from the ectopic thymic tissue or the remnants of branchial pouches. The optimal treatment strategy is still uncertain because of the rarity of the tumor. The mainstay of treatment is surgery. The role of other modalities is unclear. We present a case report of a patient with locally advanced CASTLE of the thyroid gland who was not suitable for surgery and underwent radical radiotherapy with subsequent achievement of complete remission. We also present a literature review.

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Title: Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission
Authors: Petra Kovářová, MD
Radovan Vojtíšek, MD, PhD
Michal Krčma, MD, PhD
Prof. Ondřej Daum, MD, PhD
Prof. Jan Baxa, MD, PhD
Emília Sukovská, MD
Prof. Jindřich Fínek, MD, PhD, MHA
Publication date: 01-09-2021
Publisher: Springer Berlin Heidelberg
Keyword: Radiotherapy
Published in: Strahlentherapie und Onkologie / Issue 9/2021
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-021-01800-6

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Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission

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