Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Clinical Neuroradiology
Published in: Clinical Neuroradiology 2/2015

01-10-2015 | Review Article

Presurgical MR Imaging in Epilepsy

Authors: H. Urbach, MD, H. Mast, K. Egger, MD, I. Mader, MD, PhD

Published in: Clinical Neuroradiology | Special Issue 2/2015

Login to get access

Abstract

Primary goal of magnetic resonance imaging in epilepsy patients is to detect epileptogenic lesions with small lesions best detectable on a 3D FLAIR SPACE sequence with 1 mm3 voxels. Morphometric analysis of 3D T1-weighted data sets helps to find subtle lesions and may reveal the true extent of a lesion. In further presurgical work-up, language lateralization and spatial relationship of epileptogenic lesions to eloquent cortex and white matter tracts must be evaluated. With clear left lateralization language, fMRI is sufficient; in atypical lateralizations, Wada test and electrical stimulation mapping may be added. Primary motor cortex and corticospinal tract on one and visual cortex and optic radiation on the other side are displayed with fMRI and diffusion tensor tractography. For the corticospinal tract a „global“ tracking algorithm, for the optic radiation including Meyer’ loop, which may be damaged in anterior temporal lobe resections, a probabilistic algorithm is best suited.
Literature
1.
Rosenow F, Lüders H. Presurgical evaluation of epilepsy. Brain. 2001;124:683–1700.CrossRef
2.
Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, Engel J, Jr., Forsgren L, French JA, Glynn M, Hesdorffer DC, Lee BI, Mathern GW, Moshé SL, Perucca E, Scheffer IE, Tomson T, Watanabe M, Wiebe S. A practical clinical definition of epilepsy. Epilepsia. 2014;55:475–82.CrossRefPubMed
3.
Blümcke I, Thom M, Aronica E, Armstrong DD, Bartolomei F, Bernasconi A, Bernasconi N, Bien CG, Cendes F, Coras R, Cross JH, Jacques TS, Kahane P, Mathern GW, Miyata H, Moshé SL, Oz B, Özkara Ç, Perucca E, Sisodiya S, Wiebe S, Spreafico R. International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a task force report from the ILAE commission on diagnostic methods. Epilepsia. 2013;54:1315–29.CrossRefPubMed
4.
Bien CG, Szinai M, Wagner J, Clusmann H, Becker AJ, Urbach H. Characteristics and surgical outcome of patients with refractory MRI-negative epilepsies. Arch Neurol. 2009;66:1491–9.PubMed
5.
Urbach H, Huppertz HJ, Schwarzwald R, Becker AJ, Wagner J, Delsous Bahri M, Tschampa HJ. Is the type and extent of hippocampal sclerosis measurable on high-resolution MRI? Neuroradiology. 2014;56:731–5.
6.
Bien CG, Raabe AL, Schramm J, Becker A, Urbach H, Elger CE. Trends in presurgical evaluation and surgical treatment of epilepsy at one centre from 1988–2009. J Neurol Neurosurg Psychiatry. 2013;84:54–61.CrossRefPubMed
7.
Wellmer J, Quesada CM, Rothe L, Elger CE, Bien CG, Urbach H. Proposal for a magnetic resonance imaging protocol for the detection of epileptogenic lesions at early outpatient stages. Epilepsia. 2013;44:1977–87.CrossRef
8.
Huppertz HJ. Morphometric MRI analysis. In: Urbach H, Editor. MRI in epilepsy. New York: Springer Heidelberg; 2013. pp. 73–84.
9.
Wagner J, Weber B, Urbach H, Elger CE, Huppertz HJ. Morphometric MRI analysis improves detection of focal cortical dysplasia type II. Brain. 2011;134(Pt 10):2844–54.
10.
Huppertz HJ, Wellmer J, Staack AM, Altenmüller DM, Urbach H, Kröll J. Voxel-based 3D MRI analysis helps to detect subtle forms of subcortical band heterotopia. Epilepsia. 2008;49(5):772–85.CrossRefPubMed
11.
12.
Springer JA, Binder JR, Hammeke TA, Swanson SJ, Frost JA, Bellgowan PS, Brewer CC, Perry HM, Morris GL, Mueller WM. Language dominance in neurologically normal and epilepsy subjects. Brain. 1999;122:2033–45.CrossRefPubMed
13.
Bauer P, Reitsma JB, Houweling BM, Ferrier CH, Ramsey NF. Can fMRI safely replace the Wada test for preoperative assessment of language lateralisation? A meta-analysis and systematic review. J Neurol Neurosurg Psychiatry. 2014;85(5):581–8.CrossRefPubMed
14.
Destrieux C, Fischl B, Dale A, Halgren E. Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature. Neuroimage. 2010;53:1–15.PubMedCentralCrossRefPubMed
15.
Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage. 2003;19:1233–9.CrossRefPubMed
16.
Mori S, Crain BJ, Chacko VP, van Zilj PC. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol. 1999;45:265–9.CrossRefPubMed
17.
Reisert M, Mader I, Anastasopoulos C, Weigel M, Schnell S, Kiselev V. Global fiber reconstruction becomes practical. Neuroimage. 2011;54:955–62.CrossRefPubMed
18.
Anastasopoulos C, Reisert M, Kiselev VG, Nguyen-Thanh T, Schulze-Bonhaage A, Zentner J, Mader I. Local and global fiber tractography in patients with epilepsy. AJNR Am J Neuroradiol. 2014;35:291–6.CrossRefPubMed
19.
Winston GP, Daga P, Stretton J, Modat M, Symms MR, McEvoy AW, Ourselin S, Duncan JS. Optic radiation tractography and vision in anterior temporal lobe resection. Ann Neurol. 2012;71:334.PubMedCentralCrossRefPubMed
20.
Parker GJ, Haroon HA, Wheeler-Kingshott CA. A framework for a streamline-based probabilistic index of connectivity (PICo) using a structural interpretation of MRI diffusion measurements. J Magn Reson Imaging. 2003;18:242–54.CrossRefPubMed
21.
Kreher BW, Schnell S, Mader I, Il’yasov KA, Hennig J, Kiselev VG, Saur D. Connecting and merging fibres: pathway extraction by combining probability maps. Neuroimage. 2008;43:81–9.CrossRefPubMed
22.
Ryvlin P, Cross JHM, Rheims S. Epilepsy surgery in children and adults. Lancet Neurol. 2014;13:1114.CrossRefPubMed
23.
Kovalev D, Spreer J, Honegger J, Zentner J, Schulze-Bonhage A, Huppertz HJ. Rapid and fully automated visualization of subdural electrodes in the presurgical evaluation of epilepsy patients. AJNR Am J Neuroradiol. 2005;26:1078–83.PubMed
Metadata
Title
Presurgical MR Imaging in Epilepsy
Authors
H. Urbach, MD
H. Mast
K. Egger, MD
I. Mader, MD, PhD
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue Special Issue 2/2015
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-015-0387-x

Other articles of this Special Issue 2/2015

Clinical Neuroradiology 2/2015 Go to the issue

Review Article

MRI of the Fetal Brain

Review Article

Imaging Neurodegeneration: Steps Toward Brain Network-Based Pathophysiology and Its Potential for Multi-modal Imaging Diagnostics

Original Article

A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping

Kurzübersicht

Das Referenzzentrum für Neuroradiologie für die Hirntumorstudien der deutschen Gesellschaft für pädiatrische Onkologie und Hämatologie (GPOH)

Review Article

Intraoperative MR Imaging in Neurosurgery

Kurzübersicht

Neuroradiologische Fort- und Weiterbildung