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Published in: Clinical Neuroradiology 2/2015

01-10-2015 | Original Article

A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping

Authors: T. Lindner, M. Helle, O. Jansen

Published in: Clinical Neuroradiology | Special Issue 2/2015

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Abstract

Arterial spin labeling (ASL) is an emerging method for the assessment of perfusion in various diseases of the brain. In ASL, the magnetization of arterial blood water spins is manipulated in a complete non-invasive way before flowing into the tissue of interest. This allows absolute quantification of cerebral blood flow, thereby, presenting an alternative to contrast-enhanced methods based on computed tomography or magnetic resonance imaging. Furthermore, its potential application for flow territory mapping can provide additional information of the individual configuration of intracerebral blood flow. This article gives a brief overview of the basic ASL methodology and its approaches to image individual perfusion territories. Additionally, the utilization of ASL in a variety of cerebrovascular diseases is presented to provide examples of potential applications of (territorial) ASL in clinical routine.
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Metadata
Title
A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping
Authors
T. Lindner
M. Helle
O. Jansen
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue Special Issue 2/2015
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-015-0450-7

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